SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5oc0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8E_B_H4BB903_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 5oc0 CYTOCHROME B561
(Escherichia
coli) 		3 / 3 ARG A  59
ILE A  10
TRP A  14
 HEM  A 201 (-3.8A)
None
None
 1.21A 1m8eB-5oc0A:
undetectable		 1m8eB-5oc0A:
11.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_A_GBNA502_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 5oc0 CYTOCHROME B561
(Escherichia
coli) 		4 / 8 ARG A 169
GLY A  81
ALA A  83
TYR A   5
 HEM  A 201 (-2.6A)
None
GOL  A 204 ( 4.3A)
HEM  A 201 (-4.6A)
 0.86A 2a1hA-5oc0A:
undetectable
2a1hB-5oc0A:
undetectable		 2a1hA-5oc0A:
13.39
2a1hB-5oc0A:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COI_A_GBNA420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 5oc0 CYTOCHROME B561
(Escherichia
coli) 		5 / 10 ARG A 169
GLY A  81
THR A  80
ALA A  83
TYR A   5
 HEM  A 201 (-2.6A)
None
None
GOL  A 204 ( 4.3A)
HEM  A 201 (-4.6A)
 1.19A 2coiA-5oc0A:
undetectable
2coiB-5oc0A:
undetectable		 2coiA-5oc0A:
12.97
2coiB-5oc0A:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COI_B_GBNB420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 5oc0 CYTOCHROME B561
(Escherichia
coli) 		5 / 10 TYR A   5
ARG A 169
GLY A  81
THR A  80
ALA A  83
 HEM  A 201 (-4.6A)
HEM  A 201 (-2.6A)
None
None
GOL  A 204 ( 4.3A)
 1.18A 2coiA-5oc0A:
undetectable
2coiB-5oc0A:
undetectable		 2coiA-5oc0A:
12.97
2coiB-5oc0A:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COJ_A_GBNA420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 5oc0 CYTOCHROME B561
(Escherichia
coli) 		5 / 11 ARG A 169
GLY A  81
THR A  80
ALA A  83
TYR A   5
 HEM  A 201 (-2.6A)
None
None
GOL  A 204 ( 4.3A)
HEM  A 201 (-4.6A)
 1.20A 2cojA-5oc0A:
undetectable
2cojB-5oc0A:
undetectable		 2cojA-5oc0A:
12.97
2cojB-5oc0A:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M9Q_B_BEZB251_0
(SERINE PROTEASE
INHIBITOR
SERINE PROTEASE
SUBUNIT NS2B, SERINE
PROTEASE NS3)		 5oc0 CYTOCHROME B561
(Escherichia
coli) 		5 / 9 LEU A  97
ILE A  52
VAL A  20
ALA A 141
LEU A  93
 HEM  A 202 (-4.4A)
HEM  A 202 ( 3.8A)
None
HEM  A 202 (-3.5A)
None
 1.12A 2m9qA-5oc0A:
undetectable		 2m9qA-5oc0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_1
(PROTEASE)		 5oc0 CYTOCHROME B561
(Escherichia
coli) 		5 / 9 ARG A 129
LEU A 133
ILE A  95
VAL A 103
ILE A 100
 None
 1.19A 2r5qA-5oc0A:
undetectable		 2r5qA-5oc0A:
21.28