SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5oc9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_2
(ADENOSINE DEAMINASE)		 5oc9 -
(-) 		4 / 5 LEU A 499
LEU A 503
SER A 415
LEU A 416
 None
 0.71A 1a4lC-5oc9A:
undetectable		 1a4lC-5oc9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA799_1
(ADENOSINE KINASE)		 5oc9 -
(-) 		5 / 10 THR A  31
GLY A 145
VAL A  27
ALA A 149
GLN A 148
 None
 1.11A 1likA-5oc9A:
undetectable		 1likA-5oc9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 5oc9 -
(-) 		4 / 5 LEU A 429
VAL A 514
CYH A 513
ALA A 247
 None
None
None
79M  A 707 ( 3.7A)
 1.15A 1mz9D-5oc9A:
undetectable		 1mz9D-5oc9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_5
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 5oc9 -
(-) 		4 / 4 LEU A 429
VAL A 514
CYH A 513
ALA A 247
 None
None
None
79M  A 707 ( 3.7A)
 1.29A 1mz9E-5oc9A:
undetectable		 1mz9E-5oc9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_G_BEZG3385_0
(CES1 PROTEIN)		 5oc9 -
(-) 		3 / 3 SER A 248
VAL A 598
LEU A 602
 79M  A 707 (-3.5A)
79M  A 707 ( 4.9A)
None
 0.68A 1yajG-5oc9A:
undetectable		 1yajG-5oc9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 5oc9 -
(-) 		5 / 9 LEU A 132
LEU A 157
LEU A 158
LEU A  35
ILE A  39
 None
 1.19A 2f78A-5oc9A:
undetectable		 2f78A-5oc9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_J_ACTJ1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5oc9 -
(-) 		4 / 8 LYS A 466
LYS A 486
GLU A 487
ILE A 483
 None
 0.96A 2j9dJ-5oc9A:
3.5
2j9dK-5oc9A:
undetectable
2j9dL-5oc9A:
2.1		 2j9dJ-5oc9A:
undetectable
2j9dK-5oc9A:
undetectable
2j9dL-5oc9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D9L_A_ACTA501_0
(CTD-PEPTIDE
RNA-BINDING PROTEIN
16)		 5oc9 -
(-) 		4 / 5 ILE A 365
PRO A 362
TYR A 336
TYR A 366
 None
 1.37A 3d9lA-5oc9A:
2.9
3d9lY-5oc9A:
undetectable		 3d9lA-5oc9A:
undetectable
3d9lY-5oc9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_A_LYAA514_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 5oc9 -
(-) 		5 / 12 LEU A  23
ILE A 143
SER A 164
LEU A 161
LEU A  35
 None
 1.11A 3k2hA-5oc9A:
undetectable		 3k2hA-5oc9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU9_B_SPMB700_1
(POLYAMINE OXIDASE)		 5oc9 -
(-) 		4 / 7 GLU A 529
TYR A 491
GLU A 448
PHE A 450
 CA  A 701 ( 2.2A)
None
CA  A 702 ( 2.6A)
None
 1.29A 3ku9B-5oc9A:
3.4		 3ku9B-5oc9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW7_A_VPXA2001_1
(PROTEINASE-ACTIVATED
RECEPTOR 1, LYSOZYME)		 5oc9 -
(-) 		5 / 12 LEU A 573
LEU A 437
LEU A 433
ALA A 520
ALA A 522
 None
 1.11A 3vw7A-5oc9A:
undetectable		 3vw7A-5oc9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 5oc9 -
(-) 		4 / 7 VAL A 167
ILE A 166
TRP A  34
LEU A 151
 None
 0.98A 4l1wA-5oc9A:
undetectable		 4l1wA-5oc9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_C_QDNC602_1
(CYTOCHROME P450 2D6)		 5oc9 -
(-) 		5 / 11 LEU A 258
GLY A 506
LEU A 510
PHE A 502
ALA A 558
 None
None
None
None
79M  A 711 ( 4.3A)
 1.31A 4wnuC-5oc9A:
undetectable		 4wnuC-5oc9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB3_A_UEGA202_1
(YFIR)		 5oc9 -
(-) 		4 / 4 LEU A 161
ILE A 166
PRO A 144
LEU A 151
 None
 1.06A 5eb3A-5oc9A:
undetectable		 5eb3A-5oc9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 5oc9 -
(-) 		4 / 5 GLY A 202
PRO A 172
GLN A 125
THR A 120
 None
 1.16A 5h5fA-5oc9A:
undetectable		 5h5fA-5oc9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKW_A_TESA601_1
(AROMATASE)		 5oc9 -
(-) 		5 / 11 ILE A  39
PHE A  52
VAL A 170
VAL A  20
LEU A  23
 None
 1.41A 5jkwA-5oc9A:
undetectable		 5jkwA-5oc9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 5oc9 -
(-) 		5 / 12 PHE A 559
LEU A 405
ALA A 558
TYR A 507
LEU A 222
 None
None
79M  A 711 ( 4.3A)
None
None
 1.37A 5ljbA-5oc9A:
undetectable		 5ljbA-5oc9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_B_ZITB501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 5oc9 -
(-) 		5 / 12 ILE A 143
LEU A  23
VAL A 167
ALA A  48
GLY A  46
 None
 1.08A 5uxdB-5oc9A:
2.4		 5uxdB-5oc9A:
undetectable