SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5och'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5och -
(-) 		5 / 12 GLN B 379
ALA B 385
GLY B 307
SER B 429
LEU B 311
 None
None
Y01  B1003 ( 4.3A)
Y01  B1003 ( 3.8A)
None
 1.09A 1rjdA-5ochB:
undetectable		 1rjdA-5ochB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5och -
(-) 		5 / 12 GLN B 379
ALA B 385
GLY B 307
SER B 429
LEU B 311
 None
None
Y01  B1003 ( 4.3A)
Y01  B1003 ( 3.8A)
None
 1.05A 1rjdB-5ochB:
2.4		 1rjdB-5ochB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5och -
(-) 		5 / 12 GLN B 379
ALA B 385
GLY B 307
SER B 429
LEU B 311
 None
None
Y01  B1003 ( 4.3A)
Y01  B1003 ( 3.8A)
None
 1.04A 1rjdC-5ochB:
undetectable		 1rjdC-5ochB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2001_1
(SERUM ALBUMIN)		 5och -
(-) 		5 / 11 LEU B 274
ILE B 270
VAL B 219
GLY B 220
LEU B 148
 None
 1.38A 2bxeA-5ochB:
undetectable		 2bxeA-5ochB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_1
(PHOSPHOLIPASE A2)		 5och -
(-) 		4 / 5 VAL B 531
VAL B 530
THR B 496
ARG B 539
 None
 1.18A 3bjwA-5ochB:
undetectable		 3bjwA-5ochB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_1
(PHOSPHOLIPASE A2)		 5och -
(-) 		4 / 5 VAL B 531
VAL B 530
THR B 496
ARG B 539
 None
 1.20A 3bjwC-5ochB:
undetectable		 3bjwC-5ochB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_F_TFPF201_1
(PROTEIN S100-A4)		 5och -
(-) 		4 / 5 PHE B 140
PHE B 446
PHE B 266
PHE B 262
 None
 1.34A 3ko0F-5ochB:
undetectable
3ko0G-5ochB:
undetectable		 3ko0F-5ochB:
undetectable
3ko0G-5ochB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_F_TFPF201_1
(PROTEIN S100-A4)		 5och -
(-) 		4 / 5 PHE B 266
PHE B 262
PHE B 140
PHE B 446
 None
 1.40A 3ko0F-5ochB:
undetectable
3ko0G-5ochB:
undetectable		 3ko0F-5ochB:
undetectable
3ko0G-5ochB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5och -
(-) 		5 / 12 TYR B 481
SER B 518
VAL B 531
ILE B 666
LEU B 664
 ADP  B1001 (-3.6A)
None
None
None
None
 1.10A 3w68B-5ochB:
undetectable		 3w68B-5ochB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 5och -
(-) 		3 / 3 GLN B 260
THR B 256
THR B 257
 None
 0.81A 4fu9A-5ochB:
undetectable		 4fu9A-5ochB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUF_A_ACTA310_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 5och -
(-) 		3 / 3 GLN B 260
THR B 256
THR B 257
 None
 0.80A 4fufA-5ochB:
undetectable		 4fufA-5ochB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_A_MXMA606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5och -
(-) 		5 / 12 LEU B 612
VAL B 650
LEU B 654
ALA B 621
LEU B 620
 None
 1.31A 4m11A-5ochB:
undetectable		 4m11A-5ochB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MGH_A_ACTA1320_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 5och -
(-) 		4 / 5 VAL B 551
LEU B 520
ILE B 634
LEU B 633
 None
 0.69A 4mghA-5ochB:
undetectable		 4mghA-5ochB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB304_1
(CHITOSANASE)		 5och -
(-) 		3 / 3 GLN B 324
SER B 253
ASP B 258
 None
 0.93A 4qwpA-5ochB:
undetectable
4qwpB-5ochB:
undetectable		 4qwpA-5ochB:
undetectable
4qwpB-5ochB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 2)		 5och -
(-) 		3 / 3 PHE B 474
THR B 631
LEU B 538
 None
 0.76A 4qztA-5ochB:
undetectable		 4qztA-5ochB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 5och -
(-) 		3 / 3 ALA B 714
ASN B 717
LEU B 718
 None
 0.13A 5i1nB-5ochB:
undetectable		 5i1nB-5ochB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 5och -
(-) 		3 / 3 ALA B 714
ASN B 717
LEU B 718
 None
 0.23A 5i1oC-5ochB:
undetectable		 5i1oC-5ochB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 5och -
(-) 		3 / 3 ALA B 714
ASN B 717
LEU B 718
 None
 0.27A 5i1pA-5ochB:
undetectable		 5i1pA-5ochB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDZ_A_ADNA905_1
(ATP-CITRATE SYNTHASE)		 5och -
(-) 		4 / 6 ASP B 525
ARG B 539
LEU B 538
ASP B 537
 None
 1.15A 5tdzA-5ochB:
undetectable		 5tdzA-5ochB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPL_B_PA1B605_1
(LIPID A EXPORT
ATP-BINDING/PERMEASE
PROTEIN MSBA)		 5och -
(-) 		3 / 3 ARG B 329
ARG B 321
ARG B 367
 None
 1.08A 6bplA-5ochB:
27.8
6bplB-5ochB:
22.5		 6bplA-5ochB:
undetectable
6bplB-5ochB:
undetectable