SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ocl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CC8_A_RBFA1067_1
(VNG1446H)		 5ocl ANTI-VGLUT NANOBODY
(Lama
glama) 		3 / 3 PHE B  39
VAL B 109
TRP B 116
 None
 0.89A 2cc8A-5oclB:
undetectable		 2cc8A-5oclB:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CCB_A_RBFA1067_1
(VNG1446H)		 5ocl ANTI-VGLUT NANOBODY
(Lama
glama) 		3 / 3 PHE B  39
VAL B 109
TRP B 116
 None
 0.88A 2ccbA-5oclB:
undetectable		 2ccbA-5oclB:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VX9_A_RBFA1064_1
(DODECIN)		 5ocl ANTI-VGLUT NANOBODY
(Lama
glama) 		3 / 3 PHE B  39
VAL B 109
TRP B 116
 None
 0.89A 2vx9A-5oclB:
undetectable		 2vx9A-5oclB:
18.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXT_B_MTXB2000_1
(ANTI-METHOTREXATE
CDR1-3 GRAFT VHH)		 5ocl ANTI-VGLUT NANOBODY
(Lama
glama) 		6 / 12 VAL B   4
LEU B   6
ALA B  26
VAL B  81
ALA B 100
TYR B 115
 None
 0.74A 3qxtB-5oclB:
20.1		 3qxtB-5oclB:
73.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5ocl ANTI-VGLUT NANOBODY
(Lama
glama) 		4 / 7 ALA B  94
THR B  93
VAL B 122
GLU B  91
 None
 0.73A 5ecmD-5oclB:
undetectable		 5ecmD-5oclB:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5ocl ANTI-VGLUT NANOBODY
(Lama
glama) 		4 / 7 ALA B  94
THR B  93
VAL B 122
GLU B  91
 None
 0.83A 5ecoD-5oclB:
undetectable		 5ecoD-5oclB:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_C_FK5C201_1
(FK506-BINDING
PROTEIN 1)		 5ocl ANTI-LLAMA NANOBODY
ANTI-VGLUT NANOBODY
(Lama
glama;
Vicugna
pacos) 		5 / 10 TYR A  39
ASP A  37
TRP A 107
LEU A   6
ILE B  53
 None
 1.35A 5hw8C-5oclA:
undetectable
5hw8H-5oclA:
undetectable		 5hw8C-5oclA:
19.84
5hw8H-5oclA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZHM_B_SAMB301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 5ocl ANTI-LLAMA NANOBODY
(Vicugna
pacos) 		4 / 4 ARG A  73
SER A  52
ASP A  37
HIS A  98
 None
 1.46A 5zhmA-5oclA:
undetectable		 5zhmA-5oclA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E5Z_A_CCSA106_0
(PROTEIN/NUCLEIC ACID
DEGLYCASE DJ-1)		 5ocl ANTI-LLAMA NANOBODY
ANTI-VGLUT NANOBODY
(Vicugna
pacos;
Lama
glama) 		5 / 10 GLY A  35
GLY B  57
ASN B  59
ILE A  36
ALA A  54
 None
 0.86A 6e5zA-5oclA:
undetectable		 6e5zA-5oclA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_1
(TUBULIN BETA CHAIN)		 5ocl ANTI-LLAMA NANOBODY
(Vicugna
pacos) 		5 / 12 GLU A  90
SER A  64
PHE A  69
LEU A  82
LEU A  87
 None
 1.17A 6ew0G-5oclA:
undetectable		 6ew0G-5oclA:
21.60