SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ocp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AKD_A_CAMA420_0
(CYTOCHROME P450CAM)		 5ocp -
(-) 		5 / 11 LEU A  33
VAL A   3
GLY A   4
VAL A  87
VAL A  85
 None
 1.14A 1akdA-5ocpA:
undetectable		 1akdA-5ocpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_2
(TRANSTHYRETIN)		 5ocp -
(-) 		4 / 7 LEU A 218
ALA A 239
THR A 277
VAL A 275
 None
 1.02A 1dvxB-5ocpA:
undetectable		 1dvxB-5ocpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FAP_A_RAPA108_2
(FK506-BINDING
PROTEIN
FRAP)		 5ocp -
(-) 		4 / 8 LEU A 131
ARG A 143
PHE A 147
GLY A 111
 None
AHR  A 407 ( 2.6A)
None
None
 0.93A 1fapB-5ocpA:
undetectable		 1fapB-5ocpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PHG_A_MYTA422_1
(CYTOCHROME P450-CAM)		 5ocp -
(-) 		5 / 11 LEU A  33
VAL A   3
GLY A   4
VAL A  87
VAL A  85
 None
 1.12A 1phgA-5ocpA:
undetectable		 1phgA-5ocpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QW6_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5ocp -
(-) 		3 / 3 ARG A 143
VAL A 225
TRP A  14
 AHR  A 407 ( 2.6A)
None
AHR  A 407 ( 4.8A)
 0.90A 1qw6A-5ocpA:
undetectable		 1qw6A-5ocpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QWC_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5ocp -
(-) 		3 / 3 ARG A 143
VAL A 225
TRP A  14
 AHR  A 407 ( 2.6A)
None
AHR  A 407 ( 4.8A)
 0.94A 1qwcA-5ocpA:
undetectable		 1qwcA-5ocpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 5ocp -
(-) 		4 / 7 LEU A  33
VAL A   3
GLY A   4
VAL A  87
 None
 0.77A 1t88A-5ocpA:
undetectable		 1t88A-5ocpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VAG_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5ocp -
(-) 		3 / 3 ARG A 143
VAL A 225
TRP A  14
 AHR  A 407 ( 2.6A)
None
AHR  A 407 ( 4.8A)
 0.88A 1vagA-5ocpA:
undetectable		 1vagA-5ocpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVI_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5ocp -
(-) 		3 / 3 ARG A 143
VAL A 225
TRP A  14
 AHR  A 407 ( 2.6A)
None
AHR  A 407 ( 4.8A)
 0.87A 1zviA-5ocpA:
undetectable		 1zviA-5ocpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1N_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 5ocp -
(-) 		5 / 11 LEU A  33
VAL A   3
GLY A   4
VAL A  87
VAL A  85
 None
 1.21A 2a1nA-5ocpA:
undetectable		 2a1nA-5ocpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 5ocp -
(-) 		5 / 10 LEU A  33
VAL A   3
GLY A   4
VAL A  87
VAL A  85
 None
 1.23A 2cp4A-5ocpA:
undetectable		 2cp4A-5ocpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_A_SAMA300_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 5ocp -
(-) 		5 / 9 ALA A  59
VAL A  84
VAL A   3
GLY A   4
ILE A  86
 None
 0.87A 2z0yA-5ocpA:
3.8		 2z0yA-5ocpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5ocp -
(-) 		5 / 10 GLY A 115
GLN A 116
VAL A 150
VAL A 241
VAL A 275
 None
None
GOL  A 404 ( 4.1A)
None
None
 1.26A 3fhjB-5ocpA:
undetectable		 3fhjB-5ocpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5ocp -
(-) 		5 / 10 GLY A 115
GLN A 116
VAL A 150
VAL A 241
VAL A 275
 None
None
GOL  A 404 ( 4.1A)
None
None
 1.26A 3fhjC-5ocpA:
undetectable		 3fhjC-5ocpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5ocp -
(-) 		5 / 9 GLY A 115
GLN A 116
VAL A 150
VAL A 241
VAL A 275
 None
None
GOL  A 404 ( 4.1A)
None
None
 1.29A 3fi0C-5ocpA:
undetectable		 3fi0C-5ocpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_B_T44B128_1
(TRANSTHYRETIN)		 5ocp -
(-) 		4 / 7 LEU A 218
ALA A 239
THR A 277
VAL A 275
 None
 0.97A 3ozkB-5ocpA:
undetectable		 3ozkB-5ocpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A202_1
(POL POLYPROTEIN)		 5ocp -
(-) 		5 / 9 ALA A 144
ILE A 151
GLY A 115
ILE A 114
LEU A 131
 None
 1.03A 3u7sA-5ocpA:
undetectable		 3u7sA-5ocpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_B_ZPCB1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5ocp -
(-) 		5 / 12 PHE A 107
ILE A  86
GLU A 110
GLU A  11
PHE A  18
 None
None
None
AHR  A 407 ( 3.5A)
None
 1.40A 4a97A-5ocpA:
undetectable
4a97B-5ocpA:
undetectable		 4a97A-5ocpA:
undetectable
4a97B-5ocpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5ocp -
(-) 		4 / 8 ILE A  53
ARG A  50
PRO A  64
TRP A  70
 None
 1.28A 4f4dB-5ocpA:
4.5		 4f4dB-5ocpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_1
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 5ocp -
(-) 		3 / 3 ASP A  88
ARG A  89
ASP A 223
 AHR  A 407 ( 2.6A)
FUB  A 408 ( 3.9A)
AHR  A 407 ( 2.8A)
 0.87A 4fzvA-5ocpA:
undetectable		 4fzvA-5ocpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 5ocp -
(-) 		5 / 9 LEU A  33
VAL A   3
GLY A   4
VAL A  87
VAL A  85
 None
 1.15A 5cp4A-5ocpA:
undetectable		 5cp4A-5ocpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_A_AG2A501_1
(ARGININE/AGMATINE
ANTIPORTER)		 5ocp -
(-) 		4 / 6 GLY A 146
ASN A 148
ILE A 114
TRP A 192
 None
 1.11A 5j4nA-5ocpA:
undetectable		 5j4nA-5ocpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 5ocp -
(-) 		3 / 3 ASP A  88
ARG A  89
ASP A 223
 AHR  A 407 ( 2.6A)
FUB  A 408 ( 3.9A)
AHR  A 407 ( 2.8A)
 0.85A 5zvgA-5ocpA:
undetectable		 5zvgA-5ocpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 5ocp -
(-) 		3 / 3 ASP A  88
ARG A  89
ASP A 223
 AHR  A 407 ( 2.6A)
FUB  A 408 ( 3.9A)
AHR  A 407 ( 2.8A)
 0.88A 5zvgB-5ocpA:
2.2		 5zvgB-5ocpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWO_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 5ocp -
(-) 		5 / 9 ASP A  32
ALA A  54
GLY A   4
PHE A  52
GLY A  56
 None
 1.27A 6awoA-5ocpA:
undetectable		 6awoA-5ocpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWQ_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 5ocp -
(-) 		5 / 9 ASP A  32
ALA A  54
GLY A   4
PHE A  52
GLY A  56
 None
 1.28A 6awqA-5ocpA:
undetectable		 6awqA-5ocpA:
undetectable