SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ocr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D4S_A_TIMA401_2
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 5ocr KAPPA-CARRAGEENASE
(Zobellia
galactanivorans) 		3 / 3 THR A  92
SER A 295
PHE A 112
 None
 0.80A 3d4sA-5ocrA:
undetectable		 3d4sA-5ocrA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5ocr KAPPA-CARRAGEENASE
(Zobellia
galactanivorans) 		5 / 12 LEU A 208
GLU A 241
ALA A 243
ASP A 182
LEU A 183
 None
 1.31A 3ou6D-5ocrA:
undetectable		 3ou6D-5ocrA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PST_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5ocr KAPPA-CARRAGEENASE
(Zobellia
galactanivorans) 		3 / 3 ILE A 292
ASP A 131
ARG A  94
 None
 0.83A 4pstA-5ocrA:
undetectable		 4pstA-5ocrA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 5ocr KAPPA-CARRAGEENASE
(Zobellia
galactanivorans) 		4 / 6 LEU A 185
TYR A 249
LYS A 248
GLU A 206
 None
 1.19A 4z4gA-5ocrA:
undetectable		 4z4gA-5ocrA:
14.77