SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5odd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DTA_B_ADNB401_1 (APH(2'')-ID)	5odd	MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 26 (Homo sapiens)	4 / 8	PRO A 8 ILE A 11 LEU A 38 ILE A 43	None	0.86A	4dtaB-5oddA: undetectable	4dtaB-5oddA: 14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K50_A_ACTA502_0 (RNA POLYMERASE 3D-POL)	5odd	MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 26 (Homo sapiens)	3 / 3	ARG A 78 LYS A 75 LYS A 74	None	1.24A	4k50A-5oddA: undetectable	4k50A-5oddA: 10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K50_E_ACTE502_0 (RNA POLYMERASE 3D-POL)	5odd	MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 26 (Homo sapiens)	3 / 3	ARG A 78 LYS A 75 LYS A 74	None	1.15A	4k50E-5oddA: undetectable	4k50E-5oddA: 10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K50_I_ACTI506_0 (RNA POLYMERASE 3D-POL)	5odd	MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 26 (Homo sapiens)	3 / 3	ARG A 78 LYS A 75 LYS A 74	None	1.20A	4k50I-5oddA: undetectable	4k50I-5oddA: 10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5W4Z_A_RBFA502_2 (RIBOFLAVIN LYASE)	5odd	MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 26 (Homo sapiens)	4 / 5	ASN A 24 GLN A 22 ASP A 20 ARG A 26	None	1.49A	5w4zA-5oddA: undetectable	5w4zA-5oddA: 15.79

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4DTA_B_ADNB401_1","APH(2'')-ID","5odd","MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 26","Homo sapiens",4,"PRO A   8;ILE A  11;LEU A  38;ILE A  43","None","0.86A","4dtaB-5oddA:undetectable","4dtaB-5oddA:14.89"],["4K50_A_ACTA502_0","RNA POLYMERASE 3D-POL","5odd","MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 26","Homo sapiens",3,"ARG A  78;LYS A  75;LYS A  74","None","1.24A","4k50A-5oddA:undetectable","4k50A-5oddA:10.96"],["4K50_E_ACTE502_0","RNA POLYMERASE 3D-POL","5odd","MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 26","Homo sapiens",3,"ARG A  78;LYS A  75;LYS A  74","None","1.15A","4k50E-5oddA:undetectable","4k50E-5oddA:10.96"],["4K50_I_ACTI506_0","RNA POLYMERASE 3D-POL","5odd","MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 26","Homo sapiens",3,"ARG A  78;LYS A  75;LYS A  74","None","1.20A","4k50I-5oddA:undetectable","4k50I-5oddA:10.96"],["5W4Z_A_RBFA502_2","RIBOFLAVIN LYASE","5odd","MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 26","Homo sapiens",4,"ASN A  24;GLN A  22;ASP A  20;ARG A  26","None","1.49A","5w4zA-5oddA:undetectable","5w4zA-5oddA:15.79"]]