SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ode'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA6_0
(GRAMICIDIN A)		 5ode GLL2934 PROTEIN
(Gloeobacter
violaceus) 		3 / 3 ALA A  21
VAL A  43
TRP A  85
 None
 0.98A 1c4dA-5odeA:
undetectable
1c4dB-5odeA:
undetectable		 1c4dA-5odeA:
8.43
1c4dB-5odeA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD6_0
(GRAMICIDIN A)		 5ode GLL2934 PROTEIN
(Gloeobacter
violaceus) 		3 / 3 TRP A  85
ALA A  21
VAL A  43
 None
 0.75A 1c4dC-5odeA:
undetectable
1c4dD-5odeA:
undetectable		 1c4dC-5odeA:
8.43
1c4dD-5odeA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_0
(HYPOTHETICAL PROTEIN
RV2118C)		 5ode GLL2934 PROTEIN
(Gloeobacter
violaceus) 		5 / 12 GLY A  24
GLY A  22
ALA A 123
LEU A 284
LEU A  70
 FAD  A 400 (-2.9A)
FAD  A 400 (-3.1A)
None
None
None
 1.18A 1i9gA-5odeA:
3.6		 1i9gA-5odeA:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_1
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN))		 5ode GLL2934 PROTEIN
(Gloeobacter
violaceus) 		4 / 6 LEU A  42
PHE A 116
TYR A 106
VAL A 102
 None
 1.09A 1ibgH-5odeA:
undetectable		 1ibgH-5odeA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_A_FUAA702_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5ode GLL2934 PROTEIN
(Gloeobacter
violaceus) 		5 / 12 SER A 277
LEU A 259
VAL A  93
PHE A 100
ALA A 124
 None
 1.22A 1q23A-5odeA:
undetectable
1q23B-5odeA:
undetectable		 1q23A-5odeA:
21.19
1q23B-5odeA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB6_0
(GRAMICIDIN A)		 5ode GLL2934 PROTEIN
(Gloeobacter
violaceus) 		3 / 3 ALA A  21
VAL A  43
TRP A  85
 None
 0.91A 1tkqB-5odeA:
undetectable		 1tkqB-5odeA:
8.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMA_A_SAMA375_0
(PROBABLE TRNA
(5-METHYLAMINOMETHYL
-2-THIOURIDYLATE)-ME
THYLTRANSFERASE)		 5ode GLL2934 PROTEIN
(Gloeobacter
violaceus) 		5 / 11 GLY A  24
SER A  51
LYS A  46
GLY A 126
HIS A 252
 FAD  A 400 (-2.9A)
FAD  A 400 (-3.2A)
FAD  A 401 ( 2.7A)
FAD  A 400 ( 3.7A)
FAD  A 400 (-3.4A)
 1.38A 2hmaA-5odeA:
undetectable		 2hmaA-5odeA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5ode GLL2934 PROTEIN
(Gloeobacter
violaceus) 		4 / 8 PHE A 232
ILE A 217
MET A 227
ILE A 245
 None
 0.97A 2qwxA-5odeA:
undetectable
2qwxB-5odeA:
undetectable		 2qwxA-5odeA:
24.36
2qwxB-5odeA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_A_EPAA1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5ode GLL2934 PROTEIN
(Gloeobacter
violaceus) 		5 / 12 SER A  51
VAL A 294
ALA A 297
LEU A 284
LEU A 287
 FAD  A 400 (-3.2A)
FAD  A 400 (-3.2A)
FAD  A 400 ( 3.5A)
None
None
 1.06A 3hs6A-5odeA:
undetectable		 3hs6A-5odeA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_D_ACTD4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 5ode GLL2934 PROTEIN
(Gloeobacter
violaceus) 		4 / 5 LEU A  70
LEU A  28
GLY A  27
GLY A  23
 None
None
None
FAD  A 400 (-3.8A)
 0.66A 3si7C-5odeA:
undetectable
3si7D-5odeA:
undetectable		 3si7C-5odeA:
22.35
3si7D-5odeA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_ACTA860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5ode GLL2934 PROTEIN
(Gloeobacter
violaceus) 		4 / 5 GLY A  24
ILE A  71
VAL A 294
SER A  51
 FAD  A 400 (-2.9A)
None
FAD  A 400 (-3.2A)
FAD  A 400 (-3.2A)
 1.15A 4d33A-5odeA:
undetectable		 4d33A-5odeA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5ode GLL2934 PROTEIN
(Gloeobacter
violaceus) 		4 / 5 GLY A  24
ILE A  71
VAL A 294
SER A  51
 FAD  A 400 (-2.9A)
None
FAD  A 400 (-3.2A)
FAD  A 400 (-3.2A)
 1.16A 4d33B-5odeA:
undetectable		 4d33B-5odeA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_E_SAME301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 5ode GLL2934 PROTEIN
(Gloeobacter
violaceus) 		5 / 12 GLY A  27
GLY A  24
GLY A  74
ALA A  21
LEU A 284
 None
FAD  A 400 (-2.9A)
None
None
None
 1.12A 5c0oE-5odeA:
3.6		 5c0oE-5odeA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_2
(CDL2.3A)		 5ode GLL2934 PROTEIN
(Gloeobacter
violaceus) 		4 / 8 ILE A 187
MET A 159
ILE A 245
LEU A 205
 None
 0.99A 5ieoA-5odeA:
undetectable		 5ieoA-5odeA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_G_CHDG401_0
(BILE SALT HYDROLASE)		 5ode GLL2934 PROTEIN
(Gloeobacter
violaceus) 		5 / 10 LEU A  57
ILE A  71
LEU A  28
LEU A 284
ALA A 297
 FAD  A 400 (-4.6A)
None
None
None
FAD  A 400 ( 3.5A)
 1.27A 5y7pG-5odeA:
undetectable		 5y7pG-5odeA:
21.20