SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5odo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_A_CHDA1150_0
(ALCOHOL
DEHYDROGENASE)		 5odo ISOMERASE
(Rhodococcus
erythropolis) 		5 / 11 SER A 225
LEU A  78
LEU A  19
LEU A  90
ILE A 234
 None
 1.41A 1ee2A-5odoA:
3.3		 1ee2A-5odoA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_1
(ALCOHOL
DEHYDROGENASE)		 5odo ISOMERASE
(Rhodococcus
erythropolis) 		5 / 11 SER A 225
LEU A  78
LEU A  19
LEU A  90
ILE A 234
 None
 1.40A 1ee2B-5odoA:
3.3		 1ee2B-5odoA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3004_1
(SERUM ALBUMIN)		 5odo ISOMERASE
(Rhodococcus
erythropolis) 		4 / 6 PHE A 295
PHE A 529
LEU A 498
VAL A 270
 None
 1.05A 1hk1A-5odoA:
undetectable		 1hk1A-5odoA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_H_FUAH709_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5odo ISOMERASE
(Rhodococcus
erythropolis) 		5 / 12 PHE A 529
LEU A  25
PHE A 295
VAL A 526
HIS A   7
 None
 1.15A 1q23H-5odoA:
undetectable
1q23I-5odoA:
undetectable		 1q23H-5odoA:
18.06
1q23I-5odoA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_A_SAMA501_0
(BIOTIN SYNTHASE)		 5odo ISOMERASE
(Rhodococcus
erythropolis) 		5 / 12 THR A 359
GLY A 408
ILE A 371
LEU A 447
LEU A 437
 None
 1.05A 1r30A-5odoA:
undetectable		 1r30A-5odoA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_B_SAMB501_0
(BIOTIN SYNTHASE)		 5odo ISOMERASE
(Rhodococcus
erythropolis) 		5 / 12 THR A 359
GLY A 408
ILE A 371
LEU A 447
LEU A 437
 None
 1.05A 1r30B-5odoA:
undetectable		 1r30B-5odoA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FJ1_A_CTCA222_0
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 5odo ISOMERASE
(Rhodococcus
erythropolis) 		5 / 12 HIS A 401
HIS A 399
ARG A  76
ILE A 233
SER A 225
 None
None
FMT  A 607 (-3.6A)
None
None
 1.16A 2fj1A-5odoA:
undetectable		 2fj1A-5odoA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A163_1
(BETA-LACTOGLOBULIN)		 5odo ISOMERASE
(Rhodococcus
erythropolis) 		5 / 12 VAL A  93
VAL A  89
LEU A  90
ILE A 233
ILE A 234
 None
 0.89A 2gj5A-5odoA:
undetectable		 2gj5A-5odoA:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O7O_A_DXTA222_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 5odo ISOMERASE
(Rhodococcus
erythropolis) 		5 / 12 HIS A 401
HIS A 399
ARG A  76
ILE A 233
SER A 225
 None
None
FMT  A 607 (-3.6A)
None
None
 1.26A 2o7oA-5odoA:
undetectable		 2o7oA-5odoA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1003_0
(ALDEHYDE
DEHYDROGENASE A)		 5odo ISOMERASE
(Rhodococcus
erythropolis) 		4 / 5 LEU A 337
ASP A 296
ALA A 505
PHE A 257
 None
 0.95A 2opxA-5odoA:
2.3		 2opxA-5odoA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TRT_A_TACA222_1
(TETRACYCLINE
REPRESSOR CLASS D)		 5odo ISOMERASE
(Rhodococcus
erythropolis) 		5 / 11 HIS A 401
HIS A 399
ARG A  76
ILE A 233
SER A 225
 None
None
FMT  A 607 (-3.6A)
None
None
 1.28A 2trtA-5odoA:
undetectable		 2trtA-5odoA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VKE_A_TACA222_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 5odo ISOMERASE
(Rhodococcus
erythropolis) 		5 / 11 HIS A 401
HIS A 399
ARG A  76
ILE A 233
SER A 225
 None
None
FMT  A 607 (-3.6A)
None
None
 1.22A 2vkeA-5odoA:
0.0		 2vkeA-5odoA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XPV_A_MIYA1209_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 5odo ISOMERASE
(Rhodococcus
erythropolis) 		5 / 12 HIS A 401
HIS A 399
ARG A  76
ILE A 233
SER A 225
 None
None
FMT  A 607 (-3.6A)
None
None
 1.26A 2xpvA-5odoA:
undetectable		 2xpvA-5odoA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XPW_A_OTCA222_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 5odo ISOMERASE
(Rhodococcus
erythropolis) 		5 / 12 HIS A 401
HIS A 399
ARG A  76
ILE A 233
SER A 225
 None
None
FMT  A 607 (-3.6A)
None
None
 1.24A 2xpwA-5odoA:
undetectable		 2xpwA-5odoA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_A_RBFA191_1
(LUMAZINE PROTEIN)		 5odo ISOMERASE
(Rhodococcus
erythropolis) 		5 / 12 CYH A 521
LEU A 507
GLN A 503
THR A 297
ILE A 501
 None
 1.21A 3a35A-5odoA:
undetectable		 3a35A-5odoA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)		 5odo ISOMERASE
(Rhodococcus
erythropolis) 		5 / 12 CYH A 521
LEU A 507
GLN A 503
THR A 297
ILE A 501
 None
 1.20A 3a3bA-5odoA:
undetectable		 3a3bA-5odoA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6R_B_CRNB603_1
(CREATINE KINASE
B-TYPE)		 5odo ISOMERASE
(Rhodococcus
erythropolis) 		4 / 6 THR A 359
VAL A 464
LEU A 364
SER A 467
 None
 1.25A 3b6rB-5odoA:
undetectable		 3b6rB-5odoA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1100_1
(SERUM ALBUMIN)		 5odo ISOMERASE
(Rhodococcus
erythropolis) 		4 / 4 LEU A 389
ARG A  76
LEU A 380
ALA A 192
 None
FMT  A 607 (-3.6A)
None
FMT  A 607 ( 4.4A)
 1.05A 3b9mA-5odoA:
undetectable		 3b9mA-5odoA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 5odo ISOMERASE
(Rhodococcus
erythropolis) 		3 / 3 SER A 450
GLU A 363
ASP A 462
 None
 0.80A 3dmhA-5odoA:
undetectable		 3dmhA-5odoA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_2
(ADENOSYLHOMOCYSTEINA
SE)		 5odo ISOMERASE
(Rhodococcus
erythropolis) 		3 / 3 THR A 104
GLU A  80
HIS A 541
 None
MG  A 610 ( 4.9A)
None
 0.71A 3g1uB-5odoA:
2.0		 3g1uB-5odoA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LBD_A_9CRA424_1
(RETINOIC ACID
RECEPTOR GAMMA)		 5odo ISOMERASE
(Rhodococcus
erythropolis) 		5 / 12 PHE A 344
ALA A 321
ILE A 301
SER A 305
PHE A 504
 None
 1.31A 3lbdA-5odoA:
undetectable		 3lbdA-5odoA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5odo ISOMERASE
(Rhodococcus
erythropolis) 		5 / 12 GLN A 349
VAL A 484
GLY A 345
ALA A 324
SER A 323
 None
 1.02A 3sudD-5odoA:
undetectable		 3sudD-5odoA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_J_CLMJ221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5odo ISOMERASE
(Rhodococcus
erythropolis) 		5 / 12 PHE A 529
LEU A  25
PHE A 295
VAL A 526
HIS A   7
 None
 1.10A 3u9fJ-5odoA:
undetectable
3u9fK-5odoA:
undetectable		 3u9fJ-5odoA:
18.06
3u9fK-5odoA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5odo ISOMERASE
(Rhodococcus
erythropolis) 		4 / 8 PHE A 383
HIS A 443
GLU A 445
ILE A 371
 None
FMT  A 603 ( 4.4A)
None
None
 1.21A 4cx7A-5odoA:
undetectable
4cx7B-5odoA:
undetectable		 4cx7A-5odoA:
22.83
4cx7B-5odoA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K7G_B_ACTB902_0
(3-HYDROXYPROLINE
DEHYDRATSE)		 5odo ISOMERASE
(Rhodococcus
erythropolis) 		4 / 7 ASP A  97
PRO A 226
ASP A 106
SER A  95
 None
 1.25A 4k7gB-5odoA:
undetectable		 4k7gB-5odoA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_C_ACTC202_0
(RETINOL-BINDING
PROTEIN 2)		 5odo ISOMERASE
(Rhodococcus
erythropolis) 		4 / 6 GLU A  84
THR A 538
GLN A 516
LEU A 507
 None
 1.40A 4qzuC-5odoA:
undetectable		 4qzuC-5odoA:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2G_B_CTCB222_0
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 5odo ISOMERASE
(Rhodococcus
erythropolis) 		5 / 12 HIS A 401
HIS A 399
ARG A  76
ILE A 233
SER A 225
 None
None
FMT  A 607 (-3.6A)
None
None
 1.26A 4v2gB-5odoA:
undetectable		 4v2gB-5odoA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5odo ISOMERASE
(Rhodococcus
erythropolis) 		5 / 11 ILE A 166
ALA A 199
GLU A 201
ASN A 207
TRP A 171
 None
 1.26A 5ayfA-5odoA:
undetectable		 5ayfA-5odoA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_A_ILEA601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5odo ISOMERASE
(Rhodococcus
erythropolis) 		4 / 6 ALA A 522
VAL A 526
TYR A 527
VAL A  89
 None
 0.93A 5eckA-5odoA:
undetectable		 5eckA-5odoA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5odo ISOMERASE
(Rhodococcus
erythropolis) 		4 / 7 ALA A 522
VAL A 526
TYR A 527
VAL A  89
 None
 0.81A 5ecoD-5odoA:
undetectable		 5ecoD-5odoA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB603_1
(PHIAB6 TAILSPIKE)		 5odo ISOMERASE
(Rhodococcus
erythropolis) 		3 / 3 VAL A 512
GLU A 157
GLU A 160
 None
 0.84A 5jsdB-5odoA:
undetectable
5jsdC-5odoA:
undetectable		 5jsdB-5odoA:
23.17
5jsdC-5odoA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_G_ACTG702_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 5odo ISOMERASE
(Rhodococcus
erythropolis) 		3 / 3 GLY A 221
THR A 223
ASN A  79
 MG  A 610 ( 4.7A)
MG  A 610 ( 4.7A)
None
 0.71A 5odiG-5odoA:
8.0		 5odiG-5odoA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		 5odo ISOMERASE
(Rhodococcus
erythropolis) 		5 / 12 ILE A 365
VAL A 393
LEU A 364
LEU A 444
THR A 440
 None
 1.20A 6b52A-5odoA:
1.3		 6b52A-5odoA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA826_0
(GEPHYRIN)		 5odo ISOMERASE
(Rhodococcus
erythropolis) 		3 / 3 HIS A 471
ARG A 418
ILE A 429
 None
 0.47A 6fgdA-5odoA:
3.3		 6fgdA-5odoA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_A_FJQA501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)		 5odo ISOMERASE
(Rhodococcus
erythropolis) 		5 / 10 VAL A  93
PHE A 240
ILE A  26
ALA A  22
ALA A 522
 None
 1.31A 6h1lA-5odoA:
undetectable		 6h1lA-5odoA:
19.06