SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ods'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GX8_A_RTLA1163_0
(BETA-LACTOGLOBULIN)		 5ods CLATHRIN HEAVY CHAIN
1
(Mus
musculus) 		5 / 9 LEU A 325
LEU A  15
ILE A  38
VAL A 305
PHE A 304
 None
 1.32A 1gx8A-5odsA:
undetectable		 1gx8A-5odsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5ods CLATHRIN HEAVY CHAIN
1
(Mus
musculus) 		5 / 12 ILE A 282
GLY A 314
ALA A 311
GLY A 317
HIS A  12
 None
 0.89A 1kiaA-5odsA:
undetectable		 1kiaA-5odsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5ods CLATHRIN HEAVY CHAIN
1
(Mus
musculus) 		5 / 12 ILE A 282
GLY A 314
ALA A 311
GLY A 317
HIS A  12
 None
 0.90A 1kiaB-5odsA:
undetectable		 1kiaB-5odsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5ods CLATHRIN HEAVY CHAIN
1
(Mus
musculus) 		5 / 12 ILE A 282
GLY A 314
ALA A 311
GLY A 317
HIS A  12
 None
 0.89A 1kiaC-5odsA:
undetectable		 1kiaC-5odsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5ods CLATHRIN HEAVY CHAIN
1
(Mus
musculus) 		5 / 12 ILE A 282
GLY A 314
ALA A 311
GLY A 317
HIS A  12
 None
 0.87A 1nbhB-5odsA:
2.6		 1nbhB-5odsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5ods CLATHRIN HEAVY CHAIN
1
(Mus
musculus) 		5 / 12 ILE A 282
GLY A 314
ALA A 311
GLY A 317
HIS A  12
 None
 0.85A 1nbiA-5odsA:
undetectable		 1nbiA-5odsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5ods CLATHRIN HEAVY CHAIN
1
(Mus
musculus) 		5 / 12 ILE A 282
GLY A 314
ALA A 311
GLY A 317
HIS A  12
 None
 0.87A 1nbiB-5odsA:
undetectable		 1nbiB-5odsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI517_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5ods CLATHRIN HEAVY CHAIN
1
(Mus
musculus) 		4 / 7 ILE A 391
PRO A 388
GLU A 361
ALA A 358
 None
 1.10A 1oniG-5odsA:
undetectable
1oniI-5odsA:
undetectable		 1oniG-5odsA:
undetectable
1oniI-5odsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OQ5_A_CELA701_2
(CARBONIC ANHYDRASE
II)		 5ods CLATHRIN HEAVY CHAIN
1
(Mus
musculus) 		4 / 4 HIS A 197
VAL A 220
THR A 168
LEU A 183
 None
 1.30A 1oq5A-5odsA:
undetectable		 1oq5A-5odsA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5ods CLATHRIN HEAVY CHAIN
1
(Mus
musculus) 		4 / 8 SER A 200
ARG A 157
GLN A 203
PHE A 201
 None
 1.34A 1p6kA-5odsA:
undetectable		 1p6kA-5odsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5ods CLATHRIN HEAVY CHAIN
1
(Mus
musculus) 		4 / 8 SER A 200
ARG A 157
GLN A 203
PHE A 201
 None
 1.37A 1rs6A-5odsA:
undetectable		 1rs6A-5odsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y0X_X_T44X500_2
(THYROID HORMONE
RECEPTOR BETA-1)		 5ods CLATHRIN HEAVY CHAIN
1
(Mus
musculus) 		4 / 5 ILE A   4
ARG A   8
LEU A   5
ASN A 333
 None
 1.00A 1y0xX-5odsA:
undetectable		 1y0xX-5odsA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5ods CLATHRIN HEAVY CHAIN
1
(Mus
musculus) 		4 / 8 SER A 200
ARG A 157
GLN A 203
PHE A 201
 None
 1.33A 1zzuB-5odsA:
undetectable		 1zzuB-5odsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 5ods CLATHRIN HEAVY CHAIN
1
(Mus
musculus) 		5 / 12 GLY A 179
THR A 168
ARG A 144
ALA A 149
ALA A 172
 None
 1.09A 3g89A-5odsA:
undetectable		 3g89A-5odsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_B_QELB1_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 5ods CLATHRIN HEAVY CHAIN
1
(Mus
musculus) 		5 / 11 THR A 312
ALA A 307
GLN A 265
ILE A 316
THR A 158
 None
 1.35A 3qelA-5odsA:
undetectable
3qelB-5odsA:
undetectable		 3qelA-5odsA:
13.19
3qelB-5odsA:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 5ods CLATHRIN HEAVY CHAIN
1
(Mus
musculus) 		5 / 12 MET A 181
ILE A 194
ALA A 199
VAL A 186
LEU A 183
 None
 1.20A 4qynA-5odsA:
undetectable		 4qynA-5odsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XYZ_A_ACTA103_0
(POLYUBIQUITIN-C)		 5ods CLATHRIN HEAVY CHAIN
1
(Mus
musculus) 		4 / 4 LEU A  13
ILE A 316
HIS A  12
VAL A 324
 None
 1.15A 4xyzA-5odsA:
undetectable		 4xyzA-5odsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		 5ods CLATHRIN HEAVY CHAIN
1
(Mus
musculus) 		5 / 12 THR A 312
ALA A 307
GLN A 265
ILE A 316
THR A 158
 None
 1.27A 5ewjC-5odsA:
undetectable
5ewjD-5odsA:
undetectable		 5ewjC-5odsA:
13.19
5ewjD-5odsA:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5ods CLATHRIN HEAVY CHAIN
1
(Mus
musculus) 		5 / 12 GLN A 265
LYS A  36
ASP A  35
GLY A 314
HIS A 309
 None
 1.44A 5m66C-5odsA:
undetectable		 5m66C-5odsA:
12.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_B_CVIB603_0
(ACETYLCHOLINESTERASE)		 5ods CLATHRIN HEAVY CHAIN
1
(Mus
musculus) 		4 / 7 GLN A 548
ASP A 545
TRP A 514
TYR A 510
 None
 1.07A 5ov9B-5odsA:
undetectable		 5ov9B-5odsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YVN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 5ods CLATHRIN HEAVY CHAIN
1
(Mus
musculus) 		4 / 6 LEU A 148
GLN A 182
LEU A 183
LEU A 166
 None
 1.17A 5yvnA-5odsA:
undetectable		 5yvnA-5odsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_1
(NS3 PROTEASE)		 5ods CLATHRIN HEAVY CHAIN
1
(Mus
musculus) 		5 / 9 VAL A 478
GLY A 464
LEU A 427
ARG A 481
ASP A 455
 None
 1.37A 6c2mC-5odsA:
undetectable		 6c2mC-5odsA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_B_CXQB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 5ods CLATHRIN HEAVY CHAIN
1
(Mus
musculus) 		4 / 6 VAL A 467
LEU A 448
LEU A 452
LEU A 435
 None
 0.86A 6f6sA-5odsA:
undetectable
6f6sB-5odsA:
undetectable		 6f6sA-5odsA:
22.89
6f6sB-5odsA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ods CLATHRIN HEAVY CHAIN
1
(Mus
musculus) 		4 / 6 GLN A 265
PHE A 274
LEU A 287
PHE A 204
 None
 1.31A 6nmpC-5odsA:
undetectable
6nmpJ-5odsA:
undetectable		 6nmpC-5odsA:
undetectable
6nmpJ-5odsA:
undetectable