SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5oe7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		 5oe7 UBIQUITIN
THIOESTERASE OTULIN
(Homo
sapiens) 		5 / 10 LEU A 332
VAL A 304
ILE A 302
TYR A 319
GLU A 290
 None
 1.13A 1cqpA-5oe7A:
undetectable
1cqpB-5oe7A:
undetectable		 1cqpA-5oe7A:
20.00
1cqpB-5oe7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9A_B_BEZB307_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 5oe7 UBIQUITIN
THIOESTERASE OTULIN
(Homo
sapiens) 		5 / 12 LEU A 307
ASP A 336
TYR A 340
ARG A 306
GLN A 288
 None
 1.46A 1s9aB-5oe7A:
undetectable		 1s9aB-5oe7A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1291_1
(FICOLIN-2)		 5oe7 UBIQUITIN
THIOESTERASE OTULIN
(Homo
sapiens) 		4 / 6 SER A 266
LEU A 272
ASP A 264
GLU A 287
 None
 1.17A 2j2pE-5oe7A:
undetectable
2j2pF-5oe7A:
undetectable		 2j2pE-5oe7A:
21.75
2j2pF-5oe7A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 5oe7 UBIQUITIN
THIOESTERASE OTULIN
(Homo
sapiens) 		4 / 5 LEU A 332
ALA A 130
LEU A 131
MET A 139
 None
 1.21A 2oaxA-5oe7A:
undetectable		 2oaxA-5oe7A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_1
(N-METHYLTRANSFERASE)		 5oe7 UBIQUITIN
THIOESTERASE OTULIN
(Homo
sapiens) 		3 / 3 TYR A 319
TYR A 340
GLU A 314
 None
 0.78A 3pfgA-5oe7A:
undetectable		 3pfgA-5oe7A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5oe7 UBIQUITIN
THIOESTERASE OTULIN
(Homo
sapiens) 		3 / 3 VAL A 304
SER A 308
MET A 108
 None
 0.86A 5ikqA-5oe7A:
undetectable		 5ikqA-5oe7A:
18.76