SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5oee'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB8_0
(GRAMICIDIN A)		 5oee LARGE SUBUNIT
TERMINASE
(Phage
D6E) 		3 / 3 VAL A 260
VAL A 325
TRP A 275
 None
 0.81A 1bdwA-5oeeA:
undetectable
1bdwB-5oeeA:
undetectable		 1bdwA-5oeeA:
3.94
1bdwB-5oeeA:
3.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA8_0
(GRAMICIDIN A)		 5oee LARGE SUBUNIT
TERMINASE
(Phage
D6E) 		3 / 3 VAL A  50
TRP A  24
TRP A  25
 None
 1.33A 1c4dA-5oeeA:
undetectable
1c4dB-5oeeA:
undetectable		 1c4dA-5oeeA:
3.94
1c4dB-5oeeA:
3.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1434_1
(CHITINASE)		 5oee LARGE SUBUNIT
TERMINASE
(Phage
D6E) 		3 / 3 TRP A 275
THR A 375
TYR A 379
 None
 1.22A 2a3aA-5oeeA:
undetectable		 2a3aA-5oeeA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2434_1
(CHITINASE)		 5oee LARGE SUBUNIT
TERMINASE
(Phage
D6E) 		3 / 3 TRP A 275
THR A 375
TYR A 379
 None
 1.18A 2a3aB-5oeeA:
undetectable		 2a3aB-5oeeA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)		 5oee LARGE SUBUNIT
TERMINASE
(Phage
D6E) 		3 / 3 TRP A 275
THR A 375
TYR A 379
 None
 1.24A 2a3bA-5oeeA:
undetectable		 2a3bA-5oeeA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5oee LARGE SUBUNIT
TERMINASE
(Phage
D6E) 		3 / 3 LYS A  73
ASP A 394
ASP A 385
 None
 1.06A 2br4A-5oeeA:
2.8		 2br4A-5oeeA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA8_0
(GRAMICIDIN A)		 5oee LARGE SUBUNIT
TERMINASE
(Phage
D6E) 		3 / 3 VAL A  50
TRP A  24
TRP A  25
 None
 1.41A 2xdcA-5oeeA:
undetectable
2xdcB-5oeeA:
undetectable		 2xdcA-5oeeA:
3.94
2xdcB-5oeeA:
3.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA8_0
(GRAMICIDIN A)		 5oee LARGE SUBUNIT
TERMINASE
(Phage
D6E) 		3 / 3 VAL A  50
TRP A  25
TRP A  24
 None
 1.38A 2xdcA-5oeeA:
undetectable
2xdcB-5oeeA:
undetectable		 2xdcA-5oeeA:
3.94
2xdcB-5oeeA:
3.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB8_0
(GRAMICIDIN A)		 5oee LARGE SUBUNIT
TERMINASE
(Phage
D6E) 		3 / 3 TRP A  24
VAL A  50
TRP A  25
 None
 1.37A 2xdcA-5oeeA:
undetectable
2xdcB-5oeeA:
undetectable		 2xdcA-5oeeA:
3.94
2xdcB-5oeeA:
3.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB8_0
(GRAMICIDIN A)		 5oee LARGE SUBUNIT
TERMINASE
(Phage
D6E) 		3 / 3 TRP A  25
VAL A  50
TRP A  24
 None
 1.40A 2xdcA-5oeeA:
undetectable
2xdcB-5oeeA:
undetectable		 2xdcA-5oeeA:
3.94
2xdcB-5oeeA:
3.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_C_DVAC8_0
(GRAMICIDIN A)		 5oee LARGE SUBUNIT
TERMINASE
(Phage
D6E) 		3 / 3 VAL A  21
TRP A  58
TRP A  25
 None
 1.36A 2xdcC-5oeeA:
undetectable
2xdcD-5oeeA:
undetectable		 2xdcC-5oeeA:
3.94
2xdcD-5oeeA:
3.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)		 5oee LARGE SUBUNIT
TERMINASE
(Phage
D6E) 		3 / 3 VAL A  50
TRP A  24
TRP A  25
 None
 1.42A 2y5mA-5oeeA:
undetectable
2y5mB-5oeeA:
undetectable		 2y5mA-5oeeA:
3.94
2y5mB-5oeeA:
3.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)		 5oee LARGE SUBUNIT
TERMINASE
(Phage
D6E) 		3 / 3 VAL A  50
TRP A  25
TRP A  24
 None
 1.38A 2y5mA-5oeeA:
undetectable
2y5mB-5oeeA:
undetectable		 2y5mA-5oeeA:
3.94
2y5mB-5oeeA:
3.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)		 5oee LARGE SUBUNIT
TERMINASE
(Phage
D6E) 		3 / 3 VAL A  50
TRP A  24
TRP A  25
 None
 1.42A 2y6nA-5oeeA:
undetectable
2y6nB-5oeeA:
undetectable		 2y6nA-5oeeA:
3.94
2y6nB-5oeeA:
3.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)		 5oee LARGE SUBUNIT
TERMINASE
(Phage
D6E) 		3 / 3 VAL A  50
TRP A  25
TRP A  24
 None
 1.38A 2y6nA-5oeeA:
undetectable
2y6nB-5oeeA:
undetectable		 2y6nA-5oeeA:
3.94
2y6nB-5oeeA:
3.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB8_0
(VAL-GRAMICIDIN A)		 5oee LARGE SUBUNIT
TERMINASE
(Phage
D6E) 		3 / 3 TRP A  24
VAL A  50
TRP A  25
 None
 1.39A 2y6nA-5oeeA:
undetectable
2y6nB-5oeeA:
undetectable		 2y6nA-5oeeA:
3.94
2y6nB-5oeeA:
3.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB8_0
(VAL-GRAMICIDIN A)		 5oee LARGE SUBUNIT
TERMINASE
(Phage
D6E) 		3 / 3 TRP A  25
VAL A  50
TRP A  24
 None
 1.40A 2y6nA-5oeeA:
undetectable
2y6nB-5oeeA:
undetectable		 2y6nA-5oeeA:
3.94
2y6nB-5oeeA:
3.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 5oee LARGE SUBUNIT
TERMINASE
(Phage
D6E) 		3 / 3 GLU A 303
ASP A 301
TYR A 264
 None
 0.69A 2yvlB-5oeeA:
3.4		 2yvlB-5oeeA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_B_D2VB602_1
(CYTOCHROME P450 2R1)		 5oee LARGE SUBUNIT
TERMINASE
(Phage
D6E) 		5 / 12 LEU A  78
ALA A 155
VAL A 152
THR A  48
ILE A  83
 None
 1.02A 3czhB-5oeeA:
undetectable		 3czhB-5oeeA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FZG_A_SAMA300_0
(16S RRNA METHYLASE)		 5oee LARGE SUBUNIT
TERMINASE
(Phage
D6E) 		5 / 12 THR A 198
PHE A  14
ILE A  49
LYS A  17
VAL A  21
 None
 1.28A 3fzgA-5oeeA:
undetectable		 3fzgA-5oeeA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HEC_A_STIA1_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 5oee LARGE SUBUNIT
TERMINASE
(Phage
D6E) 		4 / 4 LEU A 136
MET A  60
ILE A  75
ASP A 142
 None
 1.20A 3hecA-5oeeA:
1.3		 3hecA-5oeeA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5oee LARGE SUBUNIT
TERMINASE
(Phage
D6E) 		4 / 8 ASP A 291
ASP A 263
ASN A 400
GLU A 374
 None
NA  A 501 (-2.9A)
None
None
 1.22A 4gkiA-5oeeA:
undetectable		 4gkiA-5oeeA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_F_CAMF502_0
(CAMPHOR
5-MONOOXYGENASE)		 5oee LARGE SUBUNIT
TERMINASE
(Phage
D6E) 		4 / 4 TYR A 238
THR A 359
VAL A 411
ILE A 354
 None
 1.44A 4jx1F-5oeeA:
undetectable		 4jx1F-5oeeA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJJ_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5oee LARGE SUBUNIT
TERMINASE
(Phage
D6E) 		4 / 4 ASP A 142
LEU A  78
ARG A  80
THR A  48
 None
 1.46A 4kjjA-5oeeA:
undetectable		 4kjjA-5oeeA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5oee LARGE SUBUNIT
TERMINASE
(Phage
D6E) 		3 / 3 TYR A 379
ALA A 358
TYR A 238
 None
 0.85A 5uunB-5oeeA:
undetectable		 5uunB-5oeeA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_1
(MRNA CAPPING ENZYME
P5)		 5oee LARGE SUBUNIT
TERMINASE
(Phage
D6E) 		3 / 3 TYR A 409
ASP A 407
ASP A 263
 None
None
NA  A 501 (-2.9A)
 0.80A 5x6yA-5oeeA:
3.4		 5x6yA-5oeeA:
19.33