SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5oei'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_B_ACTB2002_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 5oei UNCHARACTERIZED
PROTEIN FAMILY
UPF0065:TAT PATHWAY
SIGNAL
(Rhodopseudomonas
palustris) 		4 / 6 SER A 169
ALA A 170
SER A 173
ASN A 216
 OOG  A 401 (-3.0A)
OOG  A 401 ( 4.8A)
OOG  A 401 (-4.6A)
OOG  A 401 (-3.1A)
 1.10A 1yvpB-5oeiA:
undetectable		 1yvpB-5oeiA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XNR_A_ACTA1001_0
(NUCLEAR
POLYADENYLATED
RNA-BINDING PROTEIN
3)		 5oei UNCHARACTERIZED
PROTEIN FAMILY
UPF0065:TAT PATHWAY
SIGNAL
(Rhodopseudomonas
palustris) 		3 / 3 SER A 155
ARG A 160
GLN A 159
 None
SO4  A 405 (-4.0A)
None
 0.88A 2xnrA-5oeiA:
2.2		 2xnrA-5oeiA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TQ8_A_TOPA2001_1
(DIHYDROFOLATE
REDUCTASE)		 5oei UNCHARACTERIZED
PROTEIN FAMILY
UPF0065:TAT PATHWAY
SIGNAL
(Rhodopseudomonas
palustris) 		5 / 9 ILE A 101
ALA A 267
LEU A 279
ILE A  61
ILE A 102
 None
 1.18A 3tq8A-5oeiA:
undetectable		 3tq8A-5oeiA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TZF_B_08DB280_1
(7,8-DIHYDROPTEROATE
SYNTHASE)		 5oei UNCHARACTERIZED
PROTEIN FAMILY
UPF0065:TAT PATHWAY
SIGNAL
(Rhodopseudomonas
palustris) 		4 / 8 PHE A  48
THR A  53
GLY A 103
PHE A 263
 OOG  A 401 (-4.0A)
None
None
None
 0.79A 3tzfB-5oeiA:
undetectable		 3tzfB-5oeiA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5oei UNCHARACTERIZED
PROTEIN FAMILY
UPF0065:TAT PATHWAY
SIGNAL
(Rhodopseudomonas
palustris) 		4 / 5 THR A  53
THR A  54
THR A 110
ASN A 137
 None
OOG  A 401 (-3.6A)
None
OOG  A 401 ( 4.8A)
 1.22A 4pgfB-5oeiA:
undetectable		 4pgfB-5oeiA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_2
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)		 5oei UNCHARACTERIZED
PROTEIN FAMILY
UPF0065:TAT PATHWAY
SIGNAL
(Rhodopseudomonas
palustris) 		4 / 5 ILE A 275
HIS A 108
TYR A  89
VAL A  93
 None
 1.20A 4s0vA-5oeiA:
undetectable		 4s0vA-5oeiA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)		 5oei UNCHARACTERIZED
PROTEIN FAMILY
UPF0065:TAT PATHWAY
SIGNAL
(Rhodopseudomonas
palustris) 		5 / 10 SER A 198
SER A 169
LEU A  57
SER A 173
TRP A 262
 OOG  A 401 (-3.1A)
OOG  A 401 (-3.0A)
None
OOG  A 401 (-4.6A)
None
 1.19A 4yiaA-5oeiA:
undetectable		 4yiaA-5oeiA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MSD_A_BEZA1202_0
(CARBOXYLIC ACID
REDUCTASE)		 5oei UNCHARACTERIZED
PROTEIN FAMILY
UPF0065:TAT PATHWAY
SIGNAL
(Rhodopseudomonas
palustris) 		4 / 5 ILE A 107
PHE A  48
SER A  82
ALA A  86
 None
OOG  A 401 (-4.0A)
None
None
 1.19A 5msdA-5oeiA:
undetectable		 5msdA-5oeiA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUJ_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 5oei UNCHARACTERIZED
PROTEIN FAMILY
UPF0065:TAT PATHWAY
SIGNAL
(Rhodopseudomonas
palustris) 		4 / 8 ALA A 267
LEU A  44
ILE A 132
VAL A 283
 None
 0.81A 5nujA-5oeiA:
undetectable		 5nujA-5oeiA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VYH_A_FOLA409_0
(S PROTEIN)		 5oei UNCHARACTERIZED
PROTEIN FAMILY
UPF0065:TAT PATHWAY
SIGNAL
(Rhodopseudomonas
palustris) 		5 / 10 TRP A 262
GLY A 103
THR A 264
ILE A 107
ALA A 109
 None
 1.29A 5vyhA-5oeiA:
undetectable		 5vyhA-5oeiA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WM7_A_ACTA603_0
(SALICYLATE-AMP
LIGASE)		 5oei UNCHARACTERIZED
PROTEIN FAMILY
UPF0065:TAT PATHWAY
SIGNAL
(Rhodopseudomonas
palustris) 		4 / 4 THR A 174
THR A 259
ALA A 260
ARG A 321
 OOG  A 401 (-3.1A)
None
None
GOL  A 407 (-4.4A)
 1.50A 5wm7A-5oeiA:
3.3		 5wm7A-5oeiA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		 5oei UNCHARACTERIZED
PROTEIN FAMILY
UPF0065:TAT PATHWAY
SIGNAL
(Rhodopseudomonas
palustris) 		5 / 9 ALA A 219
SER A 220
GLY A  52
SER A 169
GLY A 197
 None
None
OOG  A 401 (-3.6A)
OOG  A 401 (-3.0A)
OOG  A 401 ( 3.8A)
 0.94A 6bklE-5oeiA:
undetectable
6bklF-5oeiA:
undetectable
6bklG-5oeiA:
undetectable
6bklH-5oeiA:
undetectable		 6bklE-5oeiA:
10.09
6bklF-5oeiA:
10.09
6bklG-5oeiA:
10.09
6bklH-5oeiA:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_1
(-)		 5oei UNCHARACTERIZED
PROTEIN FAMILY
UPF0065:TAT PATHWAY
SIGNAL
(Rhodopseudomonas
palustris) 		5 / 12 GLY A 103
VAL A  45
THR A 174
GLY A 175
ASP A 215
 None
None
OOG  A 401 (-3.1A)
None
OOG  A 401 ( 4.7A)
 1.05A 6gngA-5oeiA:
2.1		 6gngA-5oeiA:
23.65