SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5oen'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_2
(HIV-1 PROTEASE)
5oen INTERFERON
REGULATORY FACTOR 9
SIGNAL TRANSDUCER
AND ACTIVATOR OF
TRANSCRIPTION

(Mus
musculus)
3 / 3 ARG A 236
THR B 201
VAL B 171
None
0.76A 1hxbA-5oenA:
undetectable
1hxbA-5oenA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1871_0
(FPRA)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 7 PHE A 317
PRO A 337
ALA A 369
PHE A 368
None
1.27A 1lqtA-5oenA:
undetectable
1lqtA-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1428_0
(FPRA)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 7 PHE A 317
PRO A 337
ALA A 369
PHE A 368
None
1.28A 1lquA-5oenA:
undetectable
1lquA-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_A_SALA710_1
(PROSTAGLANDIN H2
SYNTHASE-1)
5oen SIGNAL TRANSDUCER
AND ACTIVATOR OF
TRANSCRIPTION

(Mus
musculus)
4 / 7 VAL B 227
LEU B 230
ALA B 266
LEU B 269
None
0.75A 1pthA-5oenB:
undetectable
1pthA-5oenB:
9.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_B_SALB711_1
(PROSTAGLANDIN H2
SYNTHASE-1)
5oen SIGNAL TRANSDUCER
AND ACTIVATOR OF
TRANSCRIPTION

(Mus
musculus)
4 / 7 VAL B 227
LEU B 230
ALA B 266
LEU B 269
None
0.75A 1pthB-5oenB:
undetectable
1pthB-5oenB:
9.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QAB_F_RTLF2_0
(PROTEIN (RETINOL
BINDING PROTEIN))
5oen SIGNAL TRANSDUCER
AND ACTIVATOR OF
TRANSCRIPTION

(Mus
musculus)
5 / 12 GLY B 265
PHE B 268
LEU B 258
GLN B 260
HIS B 152
None
1.21A 1qabF-5oenB:
undetectable
1qabF-5oenB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_A_NCTA1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 8 THR A 228
CYH A 235
LEU A 214
MET A 364
None
1.34A 1uw6A-5oenA:
undetectable
1uw6B-5oenA:
undetectable
1uw6A-5oenA:
18.02
1uw6B-5oenA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_D_NCTD1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 8 THR A 228
CYH A 235
LEU A 214
MET A 364
None
1.36A 1uw6D-5oenA:
undetectable
1uw6E-5oenA:
undetectable
1uw6D-5oenA:
18.02
1uw6E-5oenA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_G_NCTG1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 8 THR A 228
CYH A 235
LEU A 214
MET A 364
None
1.34A 1uw6G-5oenA:
undetectable
1uw6H-5oenA:
undetectable
1uw6G-5oenA:
18.02
1uw6H-5oenA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_P_NCTP1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 8 THR A 228
CYH A 235
LEU A 214
MET A 364
None
1.30A 1uw6P-5oenA:
undetectable
1uw6Q-5oenA:
undetectable
1uw6P-5oenA:
18.02
1uw6Q-5oenA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_T_NCTT1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 8 LEU A 214
MET A 364
THR A 228
CYH A 235
None
1.33A 1uw6P-5oenA:
undetectable
1uw6T-5oenA:
undetectable
1uw6P-5oenA:
18.02
1uw6T-5oenA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 8 PHE A 339
PHE A 322
LEU A 326
PHE A 330
None
0.86A 1v54C-5oenA:
undetectable
1v54J-5oenA:
undetectable
1v54C-5oenA:
undetectable
1v54J-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 8 PHE A 339
PHE A 322
LEU A 326
PHE A 330
None
0.91A 1v54P-5oenA:
undetectable
1v54W-5oenA:
undetectable
1v54P-5oenA:
undetectable
1v54W-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)
5oen INTERFERON
REGULATORY FACTOR 9
SIGNAL TRANSDUCER
AND ACTIVATOR OF
TRANSCRIPTION

(Mus
musculus)
5 / 9 PHE A 218
PHE A 345
PHE A 253
PHE B 174
LEU A 343
None
1.44A 1wrkA-5oenA:
undetectable
1wrkB-5oenA:
undetectable
1wrkA-5oenA:
20.00
1wrkB-5oenA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_F_TFPF211_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 7 LEU A 343
PHE A 218
PHE A 345
PHE A 253
None
0.96A 1wrlE-5oenA:
undetectable
1wrlF-5oenA:
undetectable
1wrlE-5oenA:
20.00
1wrlF-5oenA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_2
(MINERALOCORTICOID
RECEPTOR)
5oen SIGNAL TRANSDUCER
AND ACTIVATOR OF
TRANSCRIPTION

(Mus
musculus)
4 / 4 LEU B 269
LEU B 219
SER B 216
LEU B 276
None
1.18A 1ya3A-5oenB:
undetectable
1ya3A-5oenB:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_2
(MINERALOCORTICOID
RECEPTOR)
5oen SIGNAL TRANSDUCER
AND ACTIVATOR OF
TRANSCRIPTION

(Mus
musculus)
4 / 4 LEU B 307
LEU B 219
SER B 216
LEU B 276
None
1.02A 1ya3A-5oenB:
undetectable
1ya3A-5oenB:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB1283_1
(CES1 PROTEIN)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 7 PRO A 336
LEU A 326
LEU A 373
PRO A 297
None
0.87A 1ya4B-5oenA:
undetectable
1ya4B-5oenA:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 8 PHE A 339
PHE A 322
LEU A 326
PHE A 330
None
0.84A 2dyrC-5oenA:
undetectable
2dyrJ-5oenA:
undetectable
2dyrC-5oenA:
undetectable
2dyrJ-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 8 PHE A 339
PHE A 322
LEU A 326
PHE A 330
None
0.89A 2dyrP-5oenA:
undetectable
2dyrW-5oenA:
undetectable
2dyrP-5oenA:
undetectable
2dyrW-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 7 PHE A 339
PHE A 322
LEU A 326
PHE A 330
None
0.88A 2eikC-5oenA:
undetectable
2eikJ-5oenA:
undetectable
2eikC-5oenA:
undetectable
2eikJ-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 8 PHE A 339
PHE A 322
LEU A 326
PHE A 330
None
0.86A 2eilC-5oenA:
undetectable
2eilJ-5oenA:
undetectable
2eilC-5oenA:
undetectable
2eilJ-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 7 PHE A 339
PHE A 322
LEU A 326
PHE A 330
None
0.92A 2eimP-5oenA:
undetectable
2eimW-5oenA:
undetectable
2eimP-5oenA:
undetectable
2eimW-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_C_CHDC1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 5 PHE A 339
PHE A 322
LEU A 326
PHE A 330
None
0.83A 2y69C-5oenA:
undetectable
2y69J-5oenA:
undetectable
2y69C-5oenA:
undetectable
2y69J-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_P_CHDP1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 5 PHE A 339
PHE A 322
LEU A 326
PHE A 330
None
0.81A 2y69P-5oenA:
undetectable
2y69W-5oenA:
undetectable
2y69P-5oenA:
undetectable
2y69W-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 6 PHE A 339
PHE A 322
LEU A 326
PHE A 330
None
1.01A 3ablP-5oenA:
undetectable
3ablW-5oenA:
undetectable
3ablP-5oenA:
undetectable
3ablW-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 5 PHE A 339
PHE A 322
LEU A 326
PHE A 330
None
0.84A 3abmC-5oenA:
undetectable
3abmJ-5oenA:
undetectable
3abmC-5oenA:
undetectable
3abmJ-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 5 PHE A 339
PHE A 322
LEU A 326
PHE A 330
None
0.77A 3abmP-5oenA:
undetectable
3abmW-5oenA:
undetectable
3abmP-5oenA:
undetectable
3abmW-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 5 PHE A 339
PHE A 322
LEU A 326
PHE A 330
None
0.83A 3ag3C-5oenA:
undetectable
3ag3J-5oenA:
undetectable
3ag3C-5oenA:
undetectable
3ag3J-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 8 PHE A 339
PHE A 322
LEU A 326
PHE A 330
None
0.90A 3ag4C-5oenA:
undetectable
3ag4J-5oenA:
undetectable
3ag4C-5oenA:
undetectable
3ag4J-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 7 PHE A 339
PHE A 322
LEU A 326
PHE A 330
None
0.87A 3ag4P-5oenA:
undetectable
3ag4W-5oenA:
undetectable
3ag4P-5oenA:
undetectable
3ag4W-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 7 PHE A 339
PHE A 322
LEU A 326
PHE A 330
None
0.85A 3asnC-5oenA:
undetectable
3asnJ-5oenA:
undetectable
3asnC-5oenA:
undetectable
3asnJ-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 7 PHE A 339
PHE A 322
LEU A 326
PHE A 330
None
0.88A 3asnP-5oenA:
undetectable
3asnW-5oenA:
undetectable
3asnP-5oenA:
undetectable
3asnW-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 7 PHE A 339
PHE A 322
LEU A 326
PHE A 330
None
0.89A 3asoP-5oenA:
undetectable
3asoW-5oenA:
undetectable
3asoP-5oenA:
undetectable
3asoW-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 8 LEU A 237
PHE A 218
VAL A 230
LEU A 214
None
0.86A 3uniB-5oenA:
undetectable
3uniB-5oenA:
5.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 6 PHE A 339
PHE A 322
LEU A 326
PHE A 330
None
0.84A 3wg7C-5oenA:
undetectable
3wg7J-5oenA:
undetectable
3wg7C-5oenA:
undetectable
3wg7J-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 7 PHE A 339
PHE A 322
LEU A 326
PHE A 330
None
0.88A 3x2qC-5oenA:
undetectable
3x2qJ-5oenA:
undetectable
3x2qC-5oenA:
undetectable
3x2qJ-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_A_TYLA2200_1
(CREB-BINDING PROTEIN)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 6 VAL A 273
LEU A 269
ILE A 290
VAL A 362
None
0.84A 4a9kA-5oenA:
undetectable
4a9kA-5oenA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
5 / 11 VAL A 314
SER A 293
MET A 364
LEU A 343
VAL A 284
None
1.22A 4eilA-5oenA:
undetectable
4eilA-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_C_FOLC703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
5 / 11 VAL A 314
SER A 293
MET A 364
LEU A 343
VAL A 284
None
1.23A 4eilC-5oenA:
undetectable
4eilC-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_E_FOLE703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
5 / 11 VAL A 314
SER A 293
MET A 364
LEU A 343
VAL A 284
None
1.23A 4eilE-5oenA:
undetectable
4eilE-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
5 / 11 VAL A 314
SER A 293
MET A 364
LEU A 343
VAL A 284
None
1.23A 4kyaA-5oenA:
undetectable
4kyaA-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_C_FOLC703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
5 / 10 VAL A 314
SER A 293
MET A 364
LEU A 343
VAL A 284
None
1.26A 4kyaC-5oenA:
undetectable
4kyaC-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_E_FOLE703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
5 / 11 VAL A 314
SER A 293
MET A 364
LEU A 343
VAL A 284
None
1.22A 4kyaE-5oenA:
undetectable
4kyaE-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_G_FOLG703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
5 / 11 VAL A 314
SER A 293
MET A 364
LEU A 343
VAL A 284
None
1.26A 4kyaG-5oenA:
undetectable
4kyaG-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_A_377A401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 5 GLU A 298
GLU A 315
PHE A 283
TYR A 321
None
1.48A 4twdA-5oenA:
undetectable
4twdE-5oenA:
undetectable
4twdA-5oenA:
13.64
4twdE-5oenA:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4USW_A_ACTA1470_0
(ADENYLATE CYCLASE
TYPE 10)
5oen SIGNAL TRANSDUCER
AND ACTIVATOR OF
TRANSCRIPTION

(Mus
musculus)
4 / 6 LEU B 269
LEU B 226
VAL B 227
PHE B 268
None
1.20A 4uswA-5oenB:
undetectable
4uswA-5oenB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 6 PHE A 339
PHE A 322
LEU A 326
PHE A 330
None
1.04A 5b1bC-5oenA:
undetectable
5b1bJ-5oenA:
undetectable
5b1bC-5oenA:
undetectable
5b1bJ-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 7 PHE A 339
PHE A 322
LEU A 326
PHE A 330
None
0.82A 5b1bP-5oenA:
undetectable
5b1bW-5oenA:
undetectable
5b1bP-5oenA:
undetectable
5b1bW-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_2
(WTFP-TAG,GP41)
5oen SIGNAL TRANSDUCER
AND ACTIVATOR OF
TRANSCRIPTION

(Mus
musculus)
3 / 3 LEU B 231
LEU B 234
TRP B 237
None
0.80A 5nwuA-5oenB:
undetectable
5nwuA-5oenB:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_B_ZITB501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
5 / 12 LEU A 266
LEU A 308
VAL A 284
GLY A 221
TYR A 220
None
1.14A 5uxdB-5oenA:
undetectable
5uxdB-5oenA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 5 PHE A 339
PHE A 322
LEU A 326
PHE A 330
None
0.83A 5wauC-5oenA:
undetectable
5wauJ-5oenA:
undetectable
5wauC-5oenA:
undetectable
5wauJ-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 5 PHE A 339
PHE A 322
LEU A 326
PHE A 330
None
0.82A 5wauc-5oenA:
undetectable
5wauj-5oenA:
undetectable
5wauc-5oenA:
undetectable
5wauj-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 7 PHE A 339
PHE A 322
LEU A 326
PHE A 330
None
0.83A 5x1fP-5oenA:
undetectable
5x1fW-5oenA:
undetectable
5x1fP-5oenA:
undetectable
5x1fW-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 5 PHE A 339
PHE A 322
LEU A 326
PHE A 330
None
0.75A 5xdqC-5oenA:
undetectable
5xdqJ-5oenA:
undetectable
5xdqC-5oenA:
undetectable
5xdqJ-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 5 PHE A 339
PHE A 322
LEU A 326
PHE A 330
None
0.76A 5xdqP-5oenA:
undetectable
5xdqW-5oenA:
undetectable
5xdqP-5oenA:
undetectable
5xdqW-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XU8_A_DX4A701_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 2)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 8 GLY A 281
LEU A 282
GLN A 366
ALA A 369
None
0.89A 5xu8A-5oenA:
undetectable
5xu8A-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 6 PHE A 339
PHE A 322
LEU A 326
PHE A 330
None
0.79A 5z84P-5oenA:
undetectable
5z84W-5oenA:
undetectable
5z84P-5oenA:
undetectable
5z84W-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 7 PHE A 339
PHE A 322
LEU A 326
PHE A 330
None
0.82A 5z85C-5oenA:
undetectable
5z85J-5oenA:
undetectable
5z85C-5oenA:
undetectable
5z85J-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 6 PHE A 339
PHE A 322
LEU A 326
PHE A 330
None
0.84A 5z85P-5oenA:
undetectable
5z85W-5oenA:
undetectable
5z85P-5oenA:
undetectable
5z85W-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 6 PHE A 339
PHE A 322
LEU A 326
PHE A 330
None
0.78A 5z86C-5oenA:
undetectable
5z86J-5oenA:
undetectable
5z86C-5oenA:
undetectable
5z86J-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 6 PHE A 339
PHE A 322
LEU A 326
PHE A 330
None
0.78A 5z86P-5oenA:
undetectable
5z86W-5oenA:
undetectable
5z86P-5oenA:
undetectable
5z86W-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 7 PHE A 339
PHE A 322
LEU A 326
PHE A 330
None
0.76A 5zcoC-5oenA:
undetectable
5zcoJ-5oenA:
undetectable
5zcoC-5oenA:
undetectable
5zcoJ-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 6 PHE A 339
PHE A 322
LEU A 326
PHE A 330
None
0.78A 5zcoP-5oenA:
undetectable
5zcoW-5oenA:
undetectable
5zcoP-5oenA:
undetectable
5zcoW-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 6 PHE A 339
PHE A 322
LEU A 326
PHE A 330
None
0.78A 5zcpC-5oenA:
undetectable
5zcpJ-5oenA:
undetectable
5zcpC-5oenA:
undetectable
5zcpJ-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 6 PHE A 339
PHE A 322
LEU A 326
PHE A 330
None
0.79A 5zcpP-5oenA:
undetectable
5zcpW-5oenA:
undetectable
5zcpP-5oenA:
undetectable
5zcpW-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 7 PHE A 339
PHE A 322
LEU A 326
PHE A 330
None
0.80A 5zcqC-5oenA:
undetectable
5zcqJ-5oenA:
undetectable
5zcqC-5oenA:
undetectable
5zcqJ-5oenA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5oen INTERFERON
REGULATORY FACTOR 9

(Mus
musculus)
4 / 7 PHE A 339
PHE A 322
LEU A 326
PHE A 330
None
0.81A 5zcqP-5oenA:
undetectable
5zcqW-5oenA:
undetectable
5zcqP-5oenA:
undetectable
5zcqW-5oenA:
undetectable