SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5oev'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4003_1
(SERUM ALBUMIN)		 5oev GLUTATHIONE
SYNTHETASE-LIKE
EFFECTOR 22
(GPA-GSS22-APO)
(Globodera
pallida) 		4 / 6 VAL A  54
GLY A 481
ALA A  52
LEU A  35
 None
 0.77A 1e7bB-5oevA:
undetectable		 1e7bB-5oevA:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_A_NFZA1219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5oev GLUTATHIONE
SYNTHETASE-LIKE
EFFECTOR 22
(GPA-GSS22-APO)
(Globodera
pallida) 		4 / 8 TYR A 222
PHE A 224
GLY A 160
THR A 167
 None
 0.88A 1ykiA-5oevA:
undetectable
1ykiB-5oevA:
undetectable		 1ykiA-5oevA:
18.27
1ykiB-5oevA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_B_NFZB2219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5oev GLUTATHIONE
SYNTHETASE-LIKE
EFFECTOR 22
(GPA-GSS22-APO)
(Globodera
pallida) 		4 / 8 THR A 167
TYR A 222
PHE A 224
GLY A 160
 None
 0.89A 1ykiA-5oevA:
undetectable
1ykiB-5oevA:
undetectable		 1ykiA-5oevA:
18.27
1ykiB-5oevA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_C_NFZC3219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5oev GLUTATHIONE
SYNTHETASE-LIKE
EFFECTOR 22
(GPA-GSS22-APO)
(Globodera
pallida) 		4 / 8 TYR A 222
PHE A 224
GLY A 160
THR A 167
 None
 0.88A 1ykiC-5oevA:
undetectable
1ykiD-5oevA:
undetectable		 1ykiC-5oevA:
18.27
1ykiD-5oevA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_D_NFZD4219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5oev GLUTATHIONE
SYNTHETASE-LIKE
EFFECTOR 22
(GPA-GSS22-APO)
(Globodera
pallida) 		4 / 8 THR A 167
TYR A 222
PHE A 224
GLY A 160
 None
 0.92A 1ykiC-5oevA:
undetectable
1ykiD-5oevA:
undetectable		 1ykiC-5oevA:
18.27
1ykiD-5oevA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A8T_B_ADNB252_1
(U8 SNORNA-BINDING
PROTEIN X29)		 5oev GLUTATHIONE
SYNTHETASE-LIKE
EFFECTOR 22
(GPA-GSS22-APO)
(Globodera
pallida) 		4 / 8 HIS A 460
GLY A 190
SER A 458
GLN A 457
 None
 0.78A 2a8tB-5oevA:
undetectable		 2a8tB-5oevA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2001_1
(SERUM ALBUMIN)		 5oev GLUTATHIONE
SYNTHETASE-LIKE
EFFECTOR 22
(GPA-GSS22-APO)
(Globodera
pallida) 		5 / 11 VAL A  54
GLY A 481
ALA A  52
LEU A  35
ARG A 166
 None
 1.04A 2bxgA-5oevA:
undetectable		 2bxgA-5oevA:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_B_NCAB1246_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 5oev GLUTATHIONE
SYNTHETASE-LIKE
EFFECTOR 22
(GPA-GSS22-APO)
(Globodera
pallida) 		4 / 7 GLY A 441
SER A 192
SER A 197
GLU A 196
 None
 0.79A 2c8aB-5oevA:
undetectable		 2c8aB-5oevA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_D_NCAD1247_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 5oev GLUTATHIONE
SYNTHETASE-LIKE
EFFECTOR 22
(GPA-GSS22-APO)
(Globodera
pallida) 		4 / 7 GLY A 441
SER A 192
SER A 197
GLU A 196
 None
 0.77A 2c8aD-5oevA:
undetectable		 2c8aD-5oevA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIQ_A_STIA1001_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 5oev GLUTATHIONE
SYNTHETASE-LIKE
EFFECTOR 22
(GPA-GSS22-APO)
(Globodera
pallida) 		4 / 5 LEU A 236
VAL A 246
LEU A 215
MET A 194
 None
 0.88A 2oiqA-5oevA:
undetectable		 2oiqA-5oevA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BSZ_E_RTLE177_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 5oev GLUTATHIONE
SYNTHETASE-LIKE
EFFECTOR 22
(GPA-GSS22-APO)
(Globodera
pallida) 		5 / 11 ALA A 307
ALA A  84
VAL A 452
LEU A  78
GLN A  77
 None
 1.30A 3bszE-5oevA:
undetectable		 3bszE-5oevA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5oev GLUTATHIONE
SYNTHETASE-LIKE
EFFECTOR 22
(GPA-GSS22-APO)
(Globodera
pallida) 		4 / 7 ILE A 295
PHE A 212
PHE A 214
GLY A 251
 None
 0.88A 3em0B-5oevA:
undetectable		 3em0B-5oevA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 5oev GLUTATHIONE
SYNTHETASE-LIKE
EFFECTOR 22
(GPA-GSS22-APO)
(Globodera
pallida) 		5 / 10 SER A 192
LEU A 125
ILE A 127
SER A 458
GLY A 441
 None
 1.24A 3ijxB-5oevA:
undetectable
3ijxD-5oevA:
undetectable		 3ijxB-5oevA:
17.05
3ijxD-5oevA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB262_1
(GLUTAMATE RECEPTOR 2)		 5oev GLUTATHIONE
SYNTHETASE-LIKE
EFFECTOR 22
(GPA-GSS22-APO)
(Globodera
pallida) 		5 / 10 ILE A 127
SER A 458
GLY A 441
SER A 192
LEU A 125
 None
 1.41A 3ik6B-5oevA:
undetectable
3ik6E-5oevA:
undetectable		 3ik6B-5oevA:
17.05
3ik6E-5oevA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_B_HFZB800_1
(GLUTAMATE RECEPTOR 2)		 5oev GLUTATHIONE
SYNTHETASE-LIKE
EFFECTOR 22
(GPA-GSS22-APO)
(Globodera
pallida) 		5 / 10 SER A 192
LEU A 125
ILE A 127
SER A 458
GLY A 441
 None
 1.38A 3iluB-5oevA:
undetectable
3iluE-5oevA:
undetectable		 3iluB-5oevA:
17.05
3iluE-5oevA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_B_SAMB302_0
(UNCHARACTERIZED
PROTEIN Q5LES9)		 5oev GLUTATHIONE
SYNTHETASE-LIKE
EFFECTOR 22
(GPA-GSS22-APO)
(Globodera
pallida) 		5 / 12 GLY A 481
GLY A 162
GLY A 160
SER A 192
ASN A 188
 None
 0.95A 3kkzB-5oevA:
undetectable		 3kkzB-5oevA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JI0_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5oev GLUTATHIONE
SYNTHETASE-LIKE
EFFECTOR 22
(GPA-GSS22-APO)
(Globodera
pallida) 		5 / 11 ILE A 295
LEU A 306
ALA A 114
VAL A 213
LEU A 248
 None
 1.20A 5ji0A-5oevA:
undetectable		 5ji0A-5oevA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA615_1
(PHIAB6 TAILSPIKE)		 5oev GLUTATHIONE
SYNTHETASE-LIKE
EFFECTOR 22
(GPA-GSS22-APO)
(Globodera
pallida) 		3 / 3 TYR A  80
TYR A 132
GLN A 150
 None
 1.06A 5jsdA-5oevA:
undetectable
5jsdB-5oevA:
undetectable		 5jsdA-5oevA:
7.37
5jsdB-5oevA:
7.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB606_1
(PHIAB6 TAILSPIKE)		 5oev GLUTATHIONE
SYNTHETASE-LIKE
EFFECTOR 22
(GPA-GSS22-APO)
(Globodera
pallida) 		3 / 3 TYR A  80
TYR A 132
GLN A 150
 None
 1.05A 5jsdB-5oevA:
undetectable
5jsdC-5oevA:
undetectable		 5jsdB-5oevA:
7.37
5jsdC-5oevA:
7.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 5oev GLUTATHIONE
SYNTHETASE-LIKE
EFFECTOR 22
(GPA-GSS22-APO)
(Globodera
pallida) 		5 / 12 GLU A 402
LEU A 352
LYS A 402
LEU A 391
ALA A 366
 None
 1.35A 5kbwA-5oevA:
undetectable		 5kbwA-5oevA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA406_0
(THIOREDOXIN
REDUCTASE)		 5oev GLUTATHIONE
SYNTHETASE-LIKE
EFFECTOR 22
(GPA-GSS22-APO)
(Globodera
pallida) 		3 / 3 HIS A 460
SER A 483
ARG A 172
 None
 0.89A 5u63A-5oevA:
undetectable		 5u63A-5oevA:
undetectable