SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5of2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WRK_B_TFPB203_1 (TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES)	5of2	SPORE COAT-ASSOCIATED PROTEIN N (Bacillus subtilis)	4 / 5	LEU A 224 PHE A 228 MET A 85 SER A 142	None	1.24A	1wrkB-5of2A: undetectable	1wrkB-5of2A: 25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DTZ_B_LDPB501_1 (CYTOCHROME P450 BM3 VARIANT 8C8)	5of2	SPORE COAT-ASSOCIATED PROTEIN N (Bacillus subtilis)	4 / 6	PHE A 191 ALA A 171 ALA A 230 THR A 231	None	1.13A	4dtzB-5of2A: undetectable	4dtzB-5of2A: 8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IEO_A_VDYA206_1 (CDL2.3A)	5of2	SPORE COAT-ASSOCIATED PROTEIN N (Bacillus subtilis)	5 / 12	LEU A 46 LEU A 113 PHE A 72 PHE A 70 ALA A 53	None	1.24A	5ieoA-5of2A: undetectable	5ieoA-5of2A: 24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IEP_A_VDYA201_1 (CDL2.3B)	5of2	SPORE COAT-ASSOCIATED PROTEIN N (Bacillus subtilis)	5 / 12	LEU A 46 LEU A 113 PHE A 72 PHE A 70 ALA A 53	None	1.23A	5iepA-5of2A: undetectable	5iepA-5of2A: 25.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5OF1_A_SALA301_1 (SPORE COAT-ASSOCIATED PROTEIN N)	5of2	SPORE COAT-ASSOCIATED PROTEIN N (Bacillus subtilis)	5 / 5	ALA A 53 VAL A 55 LYS A 68 PHE A 70 ILE A 198	None EDO A 301 ( 3.5A) None None None	0.34A	5of1A-5of2A: 32.5	5of1A-5of2A: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5OF1_B_SALB301_1 (SPORE COAT-ASSOCIATED PROTEIN N)	5of2	SPORE COAT-ASSOCIATED PROTEIN N (Bacillus subtilis)	4 / 5	ALA A 53 VAL A 55 PHE A 70 ILE A 198	None EDO A 301 ( 3.5A) None None	0.23A	5of1B-5of2A: 32.4	5of1B-5of2A: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5OF1_B_SALB301_1 (SPORE COAT-ASSOCIATED PROTEIN N)	5of2	SPORE COAT-ASSOCIATED PROTEIN N (Bacillus subtilis)	4 / 5	VAL A 55 LYS A 68 PHE A 70 ILE A 198	EDO A 301 ( 3.5A) None None None	0.73A	5of1B-5of2A: 32.4	5of1B-5of2A: 100.00

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1WRK_B_TFPB203_1","TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES","5of2","SPORE COAT-ASSOCIATED PROTEIN N","Bacillus subtilis",4,"LEU A 224;PHE A 228;MET A  85;SER A 142","None","1.24A","1wrkB-5of2A:undetectable","1wrkB-5of2A:25.27"],["4DTZ_B_LDPB501_1","CYTOCHROME P450 BM3 VARIANT 8C8","5of2","SPORE COAT-ASSOCIATED PROTEIN N","Bacillus subtilis",4,"PHE A 191;ALA A 171;ALA A 230;THR A 231","None","1.13A","4dtzB-5of2A:undetectable","4dtzB-5of2A:8.61"],["5IEO_A_VDYA206_1","CDL2.3A","5of2","SPORE COAT-ASSOCIATED PROTEIN N","Bacillus subtilis",5,"LEU A  46;LEU A 113;PHE A  72;PHE A  70;ALA A  53","None","1.24A","5ieoA-5of2A:undetectable","5ieoA-5of2A:24.09"],["5IEP_A_VDYA201_1","CDL2.3B","5of2","SPORE COAT-ASSOCIATED PROTEIN N","Bacillus subtilis",5,"LEU A  46;LEU A 113;PHE A  72;PHE A  70;ALA A  53","None","1.23A","5iepA-5of2A:undetectable","5iepA-5of2A:25.55"],["5OF1_A_SALA301_1","SPORE COAT-ASSOCIATED PROTEIN N","5of2","SPORE COAT-ASSOCIATED PROTEIN N","Bacillus subtilis",5,"ALA A  53;VAL A  55;LYS A  68;PHE A  70;ILE A 198","None;EDO A 301 ( 3.5A);None;None;None","0.34A","5of1A-5of2A:32.5","5of1A-5of2A:100.00"],["5OF1_B_SALB301_1","SPORE COAT-ASSOCIATED PROTEIN N","5of2","SPORE COAT-ASSOCIATED PROTEIN N","Bacillus subtilis",4,"ALA A  53;VAL A  55;PHE A  70;ILE A 198","None;EDO A 301 ( 3.5A);None;None","0.23A","5of1B-5of2A:32.4","5of1B-5of2A:100.00"],["5OF1_B_SALB301_1","SPORE COAT-ASSOCIATED PROTEIN N","5of2","SPORE COAT-ASSOCIATED PROTEIN N","Bacillus subtilis",4,"VAL A  55;LYS A  68;PHE A  70;ILE A 198","EDO A 301 ( 3.5A);None;None;None","0.73A","5of1B-5of2A:32.4","5of1B-5of2A:100.00"]]