SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ofb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CET_A_CLQA1001_0
(PROTEIN (L-LACTATE
DEHYDROGENASE))
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
5 / 9 VAL B 410
GLY B 409
ILE B 456
TYR B 450
PHE B 468
None
1.17A 1cetA-5ofbB:
undetectable
1cetA-5ofbB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
5 / 12 ILE B  97
LEU B 247
ALA B  45
ILE B  48
ILE B  50
None
1.00A 1epbA-5ofbB:
undetectable
1epbA-5ofbB:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
5 / 12 ILE B  97
LEU B 247
ALA B  45
ILE B  48
ILE B  50
None
1.01A 1epbB-5ofbB:
undetectable
1epbB-5ofbB:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_2
(TRANSTHYRETIN)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
4 / 7 LEU B 147
THR B 124
LEU B 128
THR B 119
None
0.67A 1ictD-5ofbB:
undetectable
1ictD-5ofbB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JLF_A_NVPA999_1
(HIV-1 RT A-CHAIN
HIV-1 RT B-CHAIN)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
4 / 8 LEU B 439
VAL B 397
GLY B 444
TYR B 436
None
0.95A 1jlfA-5ofbB:
undetectable
1jlfB-5ofbB:
undetectable
1jlfA-5ofbB:
9.59
1jlfB-5ofbB:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWE_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
4 / 7 LEU B 439
VAL B 397
GLY B 444
TYR B 436
None
0.91A 1lweA-5ofbB:
undetectable
1lweA-5ofbB:
8.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S14_A_NOVA1300_1
(TOPOISOMERASE IV
SUBUNIT B)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
5 / 12 ASN B  39
ASP B  42
ASP B  68
MET B  73
THR B 197
MG  B 703 ( 2.7A)
None
ATP  B 702 (-3.4A)
ATP  B 702 (-3.6A)
ATP  B 702 (-3.7A)
1.03A 1s14A-5ofbB:
9.5
1s14A-5ofbB:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S14_A_NOVA1300_1
(TOPOISOMERASE IV
SUBUNIT B)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
5 / 12 ASN B 219
SER B 218
ASP B 215
ARG B  54
ILE B 257
None
1.47A 1s14A-5ofbB:
9.5
1s14A-5ofbB:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S14_B_NOVB2300_1
(TOPOISOMERASE IV
SUBUNIT B)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
5 / 12 ASN B 219
SER B 218
ASP B 215
ARG B  54
ILE B 257
None
1.43A 1s14B-5ofbB:
10.6
1s14B-5ofbB:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1X_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
4 / 8 LEU B 439
VAL B 397
GLY B 444
TYR B 436
None
0.96A 1s1xA-5ofbB:
undetectable
1s1xA-5ofbB:
9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T3R_A_017A1200_1
(PROTEASE RETROPEPSIN)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
5 / 10 LEU B 390
GLY B  31
ALA B  34
ILE B  50
VAL B 246
None
0.94A 1t3rA-5ofbB:
undetectable
1t3rA-5ofbB:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T69_A_SHHA379_1
(HISTONE DEACETYLASE
8)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
5 / 12 ASP B  49
HIS B 260
GLY B 259
PHE B 256
ASP B 521
None
1.45A 1t69A-5ofbB:
undetectable
1t69A-5ofbB:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_A_ACTA294_0
(GLYCINE
N-METHYLTRANSFERASE)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
4 / 5 ILE B  97
LEU B 247
ALA B  34
GLU B  35
None
None
None
ATP  B 702 (-4.0A)
1.34A 1xvaA-5ofbB:
undetectable
1xvaB-5ofbB:
undetectable
1xvaA-5ofbB:
undetectable
1xvaB-5ofbB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_A_SAMA501_0
(CATECHOL-O-METHYLTRA
NSFERASE)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
5 / 12 TYR B 418
SER B  94
VAL B 292
ALA B 355
ALA B 359
None
1.21A 2avdA-5ofbB:
undetectable
2avdA-5ofbB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
5 / 12 MET B 405
ALA B 406
VAL B 372
TRP B 475
ILE B 461
None
1.20A 2dcfA-5ofbB:
undetectable
2dcfA-5ofbB:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_C_ASDC1223_1
(GLUTATHIONE
S-TRANSFERASE A2)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
4 / 8 ILE B 111
GLY B 112
LEU B 206
PHE B  62
None
0.85A 2vctC-5ofbB:
2.5
2vctC-5ofbB:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
3 / 3 TYR B  51
GLU B  53
THR B 186
None
0.98A 2y7hB-5ofbB:
undetectable
2y7hB-5ofbB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A65_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
5 / 12 MET B 405
ALA B 406
VAL B 372
TRP B 475
ILE B 461
None
1.20A 3a65A-5ofbB:
undetectable
3a65A-5ofbB:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LPS_A_NOVA901_1
(TOPOISOMERASE IV
SUBUNIT B)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
5 / 12 ASN B  39
ASP B  42
ASP B  68
MET B  73
THR B 197
MG  B 703 ( 2.7A)
None
ATP  B 702 (-3.4A)
ATP  B 702 (-3.6A)
ATP  B 702 (-3.7A)
0.92A 3lpsA-5ofbB:
10.8
3lpsA-5ofbB:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
5 / 12 LEU B 247
ILE B  50
VAL B  37
ILE B 201
LEU B 204
None
1.34A 3w67D-5ofbB:
undetectable
3w67D-5ofbB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_B_ACHB301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
4 / 8 TYR B 450
TYR B 272
TRP B 451
ARG B 459
None
1.41A 3wipB-5ofbB:
undetectable
3wipC-5ofbB:
undetectable
3wipB-5ofbB:
undetectable
3wipC-5ofbB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_C_ACHC301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
4 / 8 TYR B 450
TYR B 272
TRP B 451
ARG B 459
None
1.47A 3wipC-5ofbB:
undetectable
3wipD-5ofbB:
undetectable
3wipC-5ofbB:
undetectable
3wipD-5ofbB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
4 / 8 TYR B 418
VAL B 416
ILE B 384
ASN B 386
None
1.10A 4a97C-5ofbB:
undetectable
4a97C-5ofbB:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
5 / 12 PHE B 240
GLY B 107
GLN B 428
ARG B 389
ILE B 111
None
1.45A 4djfA-5ofbB:
undetectable
4djfA-5ofbB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_C_NCTC501_1
(CYTOCHROME P450 2A13)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
4 / 7 PHE B  66
ALA B  32
LEU B 214
LEU B  64
None
0.84A 4ejgC-5ofbB:
undetectable
4ejgC-5ofbB:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FAK_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
5 / 10 LEU B 198
ILE B 191
GLY B 196
GLY B  72
THR B 126
None
None
MG  B 704 ( 4.5A)
ATP  B 702 ( 4.5A)
None
1.05A 4fakA-5ofbB:
undetectable
4fakA-5ofbB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_B_IMNB201_1
(TRANSTHYRETIN)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
4 / 8 LEU B 147
THR B 124
LEU B 128
THR B 119
None
0.73A 4ik7B-5ofbB:
undetectable
4ik7B-5ofbB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_2
(THYROID HORMONE
RECEPTOR ALPHA)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
3 / 3 ILE B  50
MET B 253
ARG B 254
None
0.86A 4lnwA-5ofbB:
undetectable
4lnwA-5ofbB:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_2
(THYROID HORMONE
RECEPTOR ALPHA)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
3 / 3 ILE B  50
MET B 253
ARG B 254
None
0.85A 4lnxA-5ofbB:
undetectable
4lnxA-5ofbB:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
4 / 7 LEU B 147
THR B 124
LEU B 128
THR B 119
None
0.80A 4pwjB-5ofbB:
undetectable
4pwjB-5ofbB:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_I_SPMI202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
4 / 7 ASN B 373
GLU B 375
GLU B 492
TYR B 272
None
1.37A 4r87I-5ofbB:
undetectable
4r87I-5ofbB:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URN_A_NOVA2000_1
(DNA TOPOISOMERASE
IV, B SUBUNIT)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
5 / 11 ASN B  39
ASP B  42
ASP B  68
MET B  73
THR B 197
MG  B 703 ( 2.7A)
None
ATP  B 702 (-3.4A)
ATP  B 702 (-3.6A)
ATP  B 702 (-3.7A)
0.81A 4urnA-5ofbB:
11.4
4urnA-5ofbB:
13.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URN_C_NOVC2000_1
(DNA TOPOISOMERASE
IV, B SUBUNIT)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
5 / 11 ASN B  39
ASP B  42
ASP B  68
MET B  73
THR B 197
MG  B 703 ( 2.7A)
None
ATP  B 702 (-3.4A)
ATP  B 702 (-3.6A)
ATP  B 702 (-3.7A)
0.91A 4urnC-5ofbB:
11.3
4urnC-5ofbB:
13.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_ACTA605_0
(SERUM ALBUMIN)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
4 / 6 TYR B 279
HIS B 438
GLU B 435
ARG B 283
None
1.31A 4zbqA-5ofbB:
2.1
4zbqA-5ofbB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_B_4TXB201_1
(TRANSTHYRETIN)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
4 / 7 LEU B 147
THR B 124
LEU B 128
THR B 119
None
0.78A 5bojB-5ofbB:
undetectable
5bojB-5ofbB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGP_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
5 / 12 ILE B 111
ALA B  43
ALA B  40
GLY B 196
THR B 119
None
ATP  B 702 (-3.4A)
ATP  B 702 ( 4.6A)
MG  B 704 ( 4.5A)
None
1.47A 5igpA-5ofbB:
undetectable
5igpA-5ofbB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKL_B_SAMB8009_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN,HISTONE H3.1
PEPTIDE,ZINC FINGER
DOMAIN-CONTAINING
PROTEIN)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
5 / 12 GLY B 381
TYR B 394
TYR B 436
PHE B 430
LEU B 439
None
1.48A 5kklB-5ofbB:
undetectable
5kklB-5ofbB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_H_SAMH501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
5 / 10 GLY B  72
LEU B  67
VAL B 199
LEU B 198
THR B 119
ATP  B 702 ( 4.5A)
None
None
None
None
0.90A 5o96G-5ofbB:
undetectable
5o96H-5ofbB:
undetectable
5o96G-5ofbB:
undetectable
5o96H-5ofbB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNI_A_SAMA401_0
(NSP16 PROTEIN)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
5 / 12 GLY B  70
PRO B 192
GLY B 193
ASP B  68
ASP B  42
MG  B 704 (-3.8A)
None
None
ATP  B 702 (-3.4A)
None
1.23A 5yniA-5ofbB:
undetectable
5yniA-5ofbB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNM_A_SAMA401_0
(NSP16 PROTEIN)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
5 / 12 GLY B  70
PRO B 192
GLY B 193
ASP B  68
ASP B  42
MG  B 704 (-3.8A)
None
None
ATP  B 702 (-3.4A)
None
1.22A 5ynmA-5ofbB:
undetectable
5ynmA-5ofbB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo
sapiens)
3 / 3 TYR B 394
ARG B 237
THR B 233
None
0.73A 5z84J-5ofbB:
undetectable
5z84J-5ofbB:
undetectable