SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5oge'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DLS_A_MTXA188_1
(DIHYDROFOLATE
REDUCTASE)		 5oge GDP-MANNOSE
TRANSPORTER 1
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 265
SER A 102
ASN A  51
LEU A  55
TYR A 281
 None
 1.05A 1dlsA-5ogeA:
undetectable		 1dlsA-5ogeA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OSV_B_CHCB201_1
(BILE ACID RECEPTOR)		 5oge GDP-MANNOSE
TRANSPORTER 1
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 200
MET A  98
ILE A 193
ILE A 125
TYR A 281
 None
 1.50A 1osvB-5ogeA:
undetectable		 1osvB-5ogeA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OT7_B_IU5B1002_1
(BILE ACID RECEPTOR)		 5oge GDP-MANNOSE
TRANSPORTER 1
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 200
MET A  98
ILE A 193
ILE A 125
TYR A 281
 None
 1.50A 1ot7B-5ogeA:
undetectable		 1ot7B-5ogeA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RH3_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 5oge GDP-MANNOSE
TRANSPORTER 1
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 265
SER A 102
ILE A  99
LEU A  55
TYR A 281
 None
 1.20A 1rh3A-5ogeA:
undetectable		 1rh3A-5ogeA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EIG_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 5oge GDP-MANNOSE
TRANSPORTER 1
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 265
SER A 102
ASN A  51
LEU A  55
TYR A 281
 None
 1.00A 3eigA-5ogeA:
undetectable		 3eigA-5ogeA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_B_MTXB164_1
(DIHYDROFOLATE
REDUCTASE)		 5oge GDP-MANNOSE
TRANSPORTER 1
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 265
SER A 102
ILE A  99
LEU A  55
TYR A 281
 None
 1.17A 3ia4B-5ogeA:
undetectable		 3ia4B-5ogeA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_D_MTXD164_1
(DIHYDROFOLATE
REDUCTASE)		 5oge GDP-MANNOSE
TRANSPORTER 1
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 265
SER A 102
ILE A  99
LEU A  55
TYR A 281
 None
 1.16A 3ia4D-5ogeA:
undetectable		 3ia4D-5ogeA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5oge GDP-MANNOSE
TRANSPORTER 1
(Saccharomyces
cerevisiae) 		4 / 8 ASN A 288
GLY A 285
VAL A 284
PHE A 198
 None
 0.93A 4fglD-5ogeA:
undetectable		 4fglD-5ogeA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA609_0
(NADH DEHYDROGENASE,
PUTATIVE)		 5oge GDP-MANNOSE
TRANSPORTER 1
(Saccharomyces
cerevisiae) 		3 / 3 VAL A 275
SER A  20
TRP A 271
 None
 0.79A 5jwaA-5ogeA:
undetectable		 5jwaA-5ogeA:
21.05