SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ogz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRA_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 5ogz -
(-) 		5 / 12 ALA A  18
GLU A  22
ILE A 150
LEU A 154
ILE A 117
 None
 1.02A 1draB-5ogzA:
undetectable		 1draB-5ogzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RU9_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 5ogz -
(-) 		5 / 9 ALA A  15
LEU A 401
GLY A 357
PHE A 418
GLY A 419
 None
 1.42A 1ru9H-5ogzA:
undetectable
1ru9L-5ogzA:
undetectable		 1ru9H-5ogzA:
undetectable
1ru9L-5ogzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_0
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 5ogz -
(-) 		5 / 12 LEU A 401
ALA A  15
ILE A 353
SER A 354
PHE A 418
 None
 1.16A 2ejtA-5ogzA:
undetectable		 2ejtA-5ogzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA802_1
(TRANSPORTER)		 5ogz -
(-) 		4 / 6 ILE A  80
ARG A  77
ILE A 217
PHE A 151
 None
 1.07A 2q72A-5ogzA:
undetectable		 2q72A-5ogzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_1
(PROTEASE)		 5ogz -
(-) 		6 / 9 LEU A 154
GLY A 112
ILE A 113
PRO A 159
VAL A 158
ILE A 157
 None
 1.18A 2r5qA-5ogzA:
undetectable		 2r5qA-5ogzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_1
(PROTEASE)		 5ogz -
(-) 		6 / 9 LEU A 154
GLY A 112
ILE A 113
PRO A 159
VAL A 158
ILE A 157
 None
 1.19A 2r5qC-5ogzA:
undetectable		 2r5qC-5ogzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_B_NBVB1504_1
(GLUCOSYLCERAMIDASE)		 5ogz -
(-) 		5 / 11 ASN A 165
GLU A 166
TYR A 296
GLU A 355
TRP A 402
 None
 0.87A 2v3dB-5ogzA:
16.1		 2v3dB-5ogzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_2
(PHOSPHOLIPASE A2)		 5ogz -
(-) 		4 / 8 TYR A 120
ASN A 165
PHE A 418
TRP A 402
 None
 1.48A 3bjwD-5ogzA:
undetectable		 3bjwD-5ogzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZG_A_NCAA302_0
(ADP-RIBOSYL CYCLASE
1)		 5ogz -
(-) 		4 / 7 LYS A 433
LEU A 404
ASP A 406
SER A  14
 None
 1.24A 3dzgA-5ogzA:
1.3		 3dzgA-5ogzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5ogz -
(-) 		3 / 3 TYR A  58
ASP A  56
ASP A  52
 None
 0.92A 3ou7B-5ogzA:
undetectable		 3ou7B-5ogzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		 5ogz -
(-) 		4 / 6 GLY A  91
LEU A 128
TYR A 142
GLU A 145
 None
 0.99A 3w9tB-5ogzA:
undetectable		 3w9tB-5ogzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		 5ogz -
(-) 		4 / 6 GLY A  91
LEU A 128
TYR A 142
GLU A 145
 None
 0.99A 3w9tE-5ogzA:
undetectable		 3w9tE-5ogzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		 5ogz -
(-) 		4 / 6 GLY A  91
LEU A 128
TYR A 142
GLU A 145
 None
 1.00A 3w9tF-5ogzA:
undetectable		 3w9tF-5ogzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_B_ACTB1358_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 5ogz -
(-) 		4 / 7 PRO A 182
ILE A  34
GLN A 129
GLY A 133
 None
 1.00A 4a3uB-5ogzA:
12.9		 4a3uB-5ogzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_A_PXLA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 5ogz -
(-) 		4 / 7 GLY A  23
ASP A  52
GLY A  51
HIS A  40
 None
 0.80A 4c5nA-5ogzA:
3.2		 4c5nA-5ogzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_C_PXLC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 5ogz -
(-) 		4 / 8 GLY A  23
ASP A  52
GLY A  51
HIS A  40
 None
 0.73A 4c5nC-5ogzA:
2.7		 4c5nC-5ogzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_B_FOLB301_1
(FOLATE RECEPTOR
ALPHA)		 5ogz -
(-) 		3 / 3 ASP A 123
TRP A 402
SER A  79
 None
 0.99A 4lrhB-5ogzA:
undetectable		 4lrhB-5ogzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_F_FOLF301_1
(FOLATE RECEPTOR
ALPHA)		 5ogz -
(-) 		3 / 3 ASP A 123
TRP A 402
SER A  79
 None
 1.08A 4lrhF-5ogzA:
undetectable		 4lrhF-5ogzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 5ogz -
(-) 		4 / 8 LEU A 401
VAL A 442
LEU A 379
TYR A 399
 None
 0.96A 4pwdC-5ogzA:
undetectable		 4pwdC-5ogzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 5ogz -
(-) 		5 / 12 PHE A 408
ILE A  45
HIS A  40
ASP A  36
SER A  33
 None
 1.39A 4r88A-5ogzA:
5.9		 4r88A-5ogzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_B_ASDB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 5ogz -
(-) 		4 / 7 VAL A 158
TRP A 161
ILE A 213
LEU A  98
 None
 1.20A 4xo7B-5ogzA:
10.5		 4xo7B-5ogzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB3_A_UEGA202_1
(YFIR)		 5ogz -
(-) 		4 / 4 LEU A 221
ILE A 219
PRO A 253
LEU A 255
 None
 1.17A 5eb3A-5ogzA:
undetectable		 5eb3A-5ogzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JM4_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5ogz -
(-) 		4 / 4 PHE A 208
ILE A 213
GLN A 216
ARG A 209
 None
 1.44A 5jm4B-5ogzA:
0.4		 5jm4B-5ogzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR0_A_478A101_1
(PROTEASE E35D-APV)		 5ogz -
(-) 		5 / 9 GLY A 112
ILE A 113
PRO A 159
VAL A 158
ILE A 157
 None
 1.14A 5kr0A-5ogzA:
undetectable		 5kr0A-5ogzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWY_A_YNUA1101_0
(MINERALOCORTICOID
RECEPTOR)		 5ogz -
(-) 		5 / 12 LEU A 223
LEU A 221
ASN A 222
SER A 194
LEU A 198
 None
 1.21A 5mwyA-5ogzA:
undetectable		 5mwyA-5ogzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_A_SALA301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 5ogz -
(-) 		4 / 5 ALA A 215
VAL A 158
PHE A 208
ILE A 117
 None
 1.01A 5of1A-5ogzA:
undetectable		 5of1A-5ogzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_B_SALB301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 5ogz -
(-) 		4 / 5 ALA A 215
VAL A 158
PHE A 208
ILE A 117
 None
 1.01A 5of1B-5ogzA:
undetectable		 5of1B-5ogzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA612_1
(SERUM ALBUMIN)		 5ogz -
(-) 		6 / 12 GLU A 355
LEU A 251
LEU A 223
LEU A 338
ILE A 351
ALA A 292
 None
 1.38A 5v0vA-5ogzA:
undetectable		 5v0vA-5ogzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_2
(CARBONIC ANHYDRASE 2)		 5ogz -
(-) 		4 / 5 HIS A 121
HIS A 201
LEU A 251
VAL A 254
 None
 1.00A 6bc9A-5ogzA:
undetectable		 6bc9A-5ogzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM0_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5ogz -
(-) 		5 / 10 SER A 354
LEU A 255
LEU A 223
ILE A 288
GLY A 218
 None
 1.29A 6dm0B-5ogzA:
undetectable
6dm0C-5ogzA:
undetectable		 6dm0B-5ogzA:
undetectable
6dm0C-5ogzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ESM_A_PZEA307_1
(MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9)		 5ogz -
(-) 		3 / 3 TYR A  61
HIS A  57
PHE A 100
 None
 0.96A 6esmA-5ogzA:
undetectable		 6esmA-5ogzA:
undetectable