SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5oh5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA502_0
(FERROCHELATASE)		 5oh5 RIDL
(Legionella
pneumophila) 		4 / 8 PRO A  48
SER A  49
VAL A 181
GLY A 180
 None
 1.00A 2qd3A-5oh5A:
undetectable		 2qd3A-5oh5A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKZ_A_ZMRA469_2
(NEURAMINIDASE)		 5oh5 RIDL
(Legionella
pneumophila) 		4 / 6 ASP A  69
TRP A  65
ILE A  22
SER A  25
 None
 1.25A 3ckzA-5oh5A:
undetectable		 3ckzA-5oh5A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SU9_A_ACTA426_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5oh5 RIDL
(Legionella
pneumophila) 		3 / 3 GLN A 193
GLU A 113
LYS A 117
 None
 1.16A 3su9A-5oh5A:
undetectable		 3su9A-5oh5A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_A_ADNA303_1
(5'/3'-NUCLEOTIDASE
SURE)		 5oh5 RIDL
(Legionella
pneumophila) 		5 / 10 GLY A 119
ASP A 124
ALA A 130
LEU A 120
LEU A 150
 None
 1.02A 4xj7A-5oh5A:
undetectable
4xj7B-5oh5A:
undetectable		 4xj7A-5oh5A:
19.42
4xj7B-5oh5A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_D_ADND303_1
(5'/3'-NUCLEOTIDASE
SURE)		 5oh5 RIDL
(Legionella
pneumophila) 		5 / 10 LEU A 120
LEU A 150
GLY A 119
ASP A 124
ALA A 130
 None
 1.08A 4xj7C-5oh5A:
undetectable
4xj7D-5oh5A:
undetectable		 4xj7C-5oh5A:
19.42
4xj7D-5oh5A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z7F_A_FOLA201_0
(FOLATE ECF
TRANSPORTER)		 5oh5 RIDL
(Legionella
pneumophila) 		5 / 12 SER A 145
ASP A 124
THR A 125
ASN A 134
LYS A 173
 None
 1.45A 4z7fA-5oh5A:
undetectable		 4z7fA-5oh5A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_A_ACTA701_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 5oh5 RIDL
(Legionella
pneumophila) 		3 / 3 LYS A  83
LYS A  90
SER A  91
 None
 1.27A 5odiA-5oh5A:
undetectable		 5odiA-5oh5A:
16.87