SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5oh6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M4I_A_KANA500_1
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 8 ASP A  47
GLU A 155
GLY A 156
SER A 162
 None
 0.79A 1m4iA-5oh6A:
undetectable		 1m4iA-5oh6A:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 7 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.10A 1v54A-5oh6A:
undetectable
1v54C-5oh6A:
2.1		 1v54A-5oh6A:
16.89
1v54C-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 7 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.11A 1v54N-5oh6A:
undetectable
1v54P-5oh6A:
undetectable		 1v54N-5oh6A:
16.89
1v54P-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 7 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.13A 1v55A-5oh6A:
undetectable
1v55C-5oh6A:
2.1		 1v55A-5oh6A:
16.89
1v55C-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 7 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.14A 1v55C-5oh6A:
1.9
1v55N-5oh6A:
undetectable
1v55P-5oh6A:
2.0		 1v55C-5oh6A:
20.00
1v55N-5oh6A:
16.89
1v55P-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 7 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.13A 2dyrA-5oh6A:
undetectable
2dyrC-5oh6A:
2.1		 2dyrA-5oh6A:
16.89
2dyrC-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 7 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.12A 2dyrN-5oh6A:
undetectable
2dyrP-5oh6A:
undetectable		 2dyrN-5oh6A:
16.89
2dyrP-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 6 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.09A 2dysA-5oh6A:
undetectable
2dysC-5oh6A:
1.9		 2dysA-5oh6A:
16.89
2dysC-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 6 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.04A 2dysN-5oh6A:
undetectable
2dysP-5oh6A:
2.0		 2dysN-5oh6A:
16.89
2dysP-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 7 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.12A 2eijA-5oh6A:
undetectable
2eijC-5oh6A:
1.9		 2eijA-5oh6A:
16.89
2eijC-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 7 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.12A 2eijN-5oh6A:
undetectable
2eijP-5oh6A:
2.4		 2eijN-5oh6A:
16.89
2eijP-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 7 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.13A 2eikA-5oh6A:
undetectable
2eikC-5oh6A:
1.9		 2eikA-5oh6A:
16.89
2eikC-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 7 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.11A 2eikN-5oh6A:
1.7
2eikP-5oh6A:
2.0		 2eikN-5oh6A:
16.89
2eikP-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 7 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.11A 2eilA-5oh6A:
undetectable
2eilC-5oh6A:
2.1		 2eilA-5oh6A:
16.89
2eilC-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 7 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.12A 2eilN-5oh6A:
undetectable
2eilP-5oh6A:
2.0		 2eilN-5oh6A:
16.89
2eilP-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 6 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.08A 2eimA-5oh6A:
undetectable
2eimC-5oh6A:
2.0		 2eimA-5oh6A:
16.89
2eimC-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 6 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.08A 2eimN-5oh6A:
1.2
2eimP-5oh6A:
1.9		 2eimN-5oh6A:
16.89
2eimP-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 6 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.06A 2einA-5oh6A:
undetectable
2einC-5oh6A:
1.9		 2einA-5oh6A:
16.89
2einC-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 6 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.15A 2einN-5oh6A:
undetectable
2einP-5oh6A:
2.0		 2einN-5oh6A:
16.89
2einP-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CHDA1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 7 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.13A 2y69A-5oh6A:
undetectable
2y69C-5oh6A:
1.9		 2y69A-5oh6A:
16.89
2y69C-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CHDN1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 8 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.11A 2y69C-5oh6A:
1.9
2y69N-5oh6A:
undetectable
2y69P-5oh6A:
1.9		 2y69C-5oh6A:
20.00
2y69N-5oh6A:
16.89
2y69P-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 6 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.13A 2zxwA-5oh6A:
undetectable
2zxwC-5oh6A:
1.9		 2zxwA-5oh6A:
16.89
2zxwC-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 6 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.06A 2zxwN-5oh6A:
undetectable
2zxwP-5oh6A:
2.0		 2zxwN-5oh6A:
16.89
2zxwP-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 7 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.17A 3abkA-5oh6A:
undetectable
3abkC-5oh6A:
1.9		 3abkA-5oh6A:
16.89
3abkC-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 7 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.15A 3abkN-5oh6A:
undetectable
3abkP-5oh6A:
1.9		 3abkN-5oh6A:
16.89
3abkP-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 8 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.12A 3ablA-5oh6A:
undetectable
3ablC-5oh6A:
2.0
3ablP-5oh6A:
1.9		 3ablA-5oh6A:
16.89
3ablC-5oh6A:
20.00
3ablP-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 8 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.09A 3ablC-5oh6A:
2.0
3ablN-5oh6A:
undetectable
3ablP-5oh6A:
1.9		 3ablC-5oh6A:
20.00
3ablN-5oh6A:
16.89
3ablP-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 8 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.14A 3abmA-5oh6A:
undetectable
3abmC-5oh6A:
1.9
3abmP-5oh6A:
2.1		 3abmA-5oh6A:
16.89
3abmC-5oh6A:
20.00
3abmP-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 7 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.13A 3abmN-5oh6A:
undetectable
3abmP-5oh6A:
2.1		 3abmN-5oh6A:
16.89
3abmP-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 6 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.18A 3ag1N-5oh6A:
undetectable
3ag1P-5oh6A:
2.3		 3ag1N-5oh6A:
16.89
3ag1P-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 7 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.14A 3ag2A-5oh6A:
undetectable
3ag2C-5oh6A:
1.9		 3ag2A-5oh6A:
16.89
3ag2C-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 7 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.14A 3ag2N-5oh6A:
undetectable
3ag2P-5oh6A:
1.9		 3ag2N-5oh6A:
16.89
3ag2P-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 7 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.16A 3ag3A-5oh6A:
undetectable
3ag3C-5oh6A:
undetectable		 3ag3A-5oh6A:
16.89
3ag3C-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 7 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.14A 3ag3N-5oh6A:
undetectable
3ag3P-5oh6A:
undetectable		 3ag3N-5oh6A:
16.89
3ag3P-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 7 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.13A 3ag4A-5oh6A:
undetectable
3ag4C-5oh6A:
2.1		 3ag4A-5oh6A:
16.89
3ag4C-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 7 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.13A 3ag4N-5oh6A:
undetectable
3ag4P-5oh6A:
2.1		 3ag4N-5oh6A:
16.89
3ag4P-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 6 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.13A 3asnA-5oh6A:
undetectable
3asnC-5oh6A:
2.1		 3asnA-5oh6A:
16.89
3asnC-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 8 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.15A 3asoA-5oh6A:
undetectable
3asoC-5oh6A:
undetectable
3asoP-5oh6A:
2.4		 3asoA-5oh6A:
16.89
3asoC-5oh6A:
20.00
3asoP-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 8 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.14A 3asoC-5oh6A:
undetectable
3asoN-5oh6A:
undetectable
3asoP-5oh6A:
2.4		 3asoC-5oh6A:
20.00
3asoN-5oh6A:
16.89
3asoP-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BPX_B_SALB258_1
(TRANSCRIPTIONAL
REGULATOR)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		5 / 11 ALA A 178
LEU A 182
ARG A 179
PRO A 218
GLY A 221
 None
 1.47A 3bpxA-5oh6A:
undetectable
3bpxB-5oh6A:
undetectable		 3bpxA-5oh6A:
19.75
3bpxB-5oh6A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_B_VIBB223_1
(THIAMINE
PYROPHOSPHOKINASE)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 7 LEU A 199
LEU A 183
SER A 189
THR A 125
 None
 1.02A 3lm8B-5oh6A:
undetectable
3lm8D-5oh6A:
undetectable		 3lm8B-5oh6A:
18.77
3lm8D-5oh6A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SU9_A_ACTA426_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		3 / 3 GLN A 177
GLU A 113
LYS A 117
 None
 1.09A 3su9A-5oh6A:
0.4		 3su9A-5oh6A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 8 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.17A 3wg7C-5oh6A:
2.4
3wg7N-5oh6A:
undetectable
3wg7P-5oh6A:
2.3		 3wg7C-5oh6A:
20.00
3wg7N-5oh6A:
16.89
3wg7P-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 8 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.14A 3x2qA-5oh6A:
undetectable
3x2qC-5oh6A:
2.1
3x2qP-5oh6A:
2.0		 3x2qA-5oh6A:
16.89
3x2qC-5oh6A:
20.00
3x2qP-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 8 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.15A 3x2qC-5oh6A:
2.1
3x2qN-5oh6A:
undetectable
3x2qP-5oh6A:
1.9		 3x2qC-5oh6A:
20.00
3x2qN-5oh6A:
16.89
3x2qP-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		5 / 10 LEU A 120
LEU A 181
ILE A 171
THR A 125
VAL A 224
 None
 1.24A 4mk4A-5oh6A:
undetectable		 4mk4A-5oh6A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 8 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.14A 5b1aA-5oh6A:
undetectable
5b1aC-5oh6A:
2.4
5b1aP-5oh6A:
2.4		 5b1aA-5oh6A:
16.89
5b1aC-5oh6A:
20.00
5b1aP-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 7 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.16A 5b1aN-5oh6A:
undetectable
5b1aP-5oh6A:
2.4		 5b1aN-5oh6A:
16.89
5b1aP-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 8 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.15A 5b1bA-5oh6A:
1.5
5b1bC-5oh6A:
2.1
5b1bP-5oh6A:
undetectable		 5b1bA-5oh6A:
16.89
5b1bC-5oh6A:
20.00
5b1bP-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 7 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.16A 5b1bN-5oh6A:
1.9
5b1bP-5oh6A:
undetectable		 5b1bN-5oh6A:
16.89
5b1bP-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 7 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.16A 5iy5A-5oh6A:
undetectable
5iy5C-5oh6A:
2.1		 5iy5A-5oh6A:
16.89
5iy5C-5oh6A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 8 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.19A 5wauA-5oh6A:
undetectable
5wauC-5oh6A:
undetectable
5wauc-5oh6A:
undetectable		 5wauA-5oh6A:
16.89
5wauC-5oh6A:
20.00
5wauc-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 7 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.14A 5wauC-5oh6A:
undetectable
5waua-5oh6A:
undetectable
5wauc-5oh6A:
undetectable		 5wauC-5oh6A:
20.00
5waua-5oh6A:
16.89
5wauc-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 8 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.19A 5x19A-5oh6A:
undetectable
5x19C-5oh6A:
1.9
5x19P-5oh6A:
1.9		 5x19A-5oh6A:
16.89
5x19C-5oh6A:
20.00
5x19P-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 6 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.20A 5x19N-5oh6A:
undetectable
5x19P-5oh6A:
2.0		 5x19N-5oh6A:
16.89
5x19P-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 7 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.19A 5x1bA-5oh6A:
undetectable
5x1bC-5oh6A:
undetectable
5x1bP-5oh6A:
1.9		 5x1bA-5oh6A:
16.89
5x1bC-5oh6A:
20.00
5x1bP-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 7 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.20A 5x1fA-5oh6A:
undetectable
5x1fC-5oh6A:
1.9
5x1fP-5oh6A:
3.0		 5x1fA-5oh6A:
16.89
5x1fC-5oh6A:
20.00
5x1fP-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 8 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.16A 5xdqA-5oh6A:
undetectable
5xdqC-5oh6A:
2.4
5xdqP-5oh6A:
2.1		 5xdqA-5oh6A:
16.89
5xdqC-5oh6A:
20.00
5xdqP-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 8 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.14A 5xdqC-5oh6A:
2.4
5xdqN-5oh6A:
undetectable
5xdqP-5oh6A:
2.1		 5xdqC-5oh6A:
20.00
5xdqN-5oh6A:
16.89
5xdqP-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 8 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.14A 5xdxC-5oh6A:
3.0
5xdxN-5oh6A:
undetectable
5xdxP-5oh6A:
2.1		 5xdxC-5oh6A:
20.07
5xdxN-5oh6A:
16.89
5xdxP-5oh6A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 8 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.16A 5z84A-5oh6A:
undetectable
5z84C-5oh6A:
2.1
5z84P-5oh6A:
2.0		 5z84A-5oh6A:
16.89
5z84C-5oh6A:
20.00
5z84P-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 7 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.15A 5z84C-5oh6A:
2.1
5z84N-5oh6A:
undetectable
5z84P-5oh6A:
2.0		 5z84C-5oh6A:
20.00
5z84N-5oh6A:
16.89
5z84P-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 8 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.15A 5z86C-5oh6A:
2.0
5z86N-5oh6A:
undetectable
5z86P-5oh6A:
undetectable		 5z86C-5oh6A:
20.00
5z86N-5oh6A:
16.89
5z86P-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 8 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.15A 5zcoA-5oh6A:
2.6
5zcoC-5oh6A:
2.1
5zcoP-5oh6A:
3.0		 5zcoA-5oh6A:
16.89
5zcoC-5oh6A:
20.00
5zcoP-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 8 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.14A 5zcoC-5oh6A:
2.1
5zcoN-5oh6A:
undetectable
5zcoP-5oh6A:
3.0		 5zcoC-5oh6A:
20.00
5zcoN-5oh6A:
16.89
5zcoP-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 8 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.15A 5zcpA-5oh6A:
undetectable
5zcpC-5oh6A:
2.0
5zcpP-5oh6A:
2.0		 5zcpA-5oh6A:
16.89
5zcpC-5oh6A:
20.00
5zcpP-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 8 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.14A 5zcpC-5oh6A:
2.1
5zcpN-5oh6A:
undetectable
5zcpP-5oh6A:
2.0		 5zcpC-5oh6A:
20.00
5zcpN-5oh6A:
16.89
5zcpP-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 7 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.16A 5zcqN-5oh6A:
undetectable
5zcqP-5oh6A:
2.0		 5zcqN-5oh6A:
16.89
5zcqP-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 6 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.18A 6nknA-5oh6A:
undetectable
6nknC-5oh6A:
2.9		 6nknA-5oh6A:
16.89
6nknC-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 8 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.16A 6nknC-5oh6A:
2.9
6nknN-5oh6A:
1.1
6nknP-5oh6A:
undetectable		 6nknC-5oh6A:
20.00
6nknN-5oh6A:
16.89
6nknP-5oh6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5oh6 INTERAPTIN
(Legionella
pneumophila) 		4 / 7 HIS A  61
ASP A  47
THR A  46
TRP A  65
 None
 1.18A 6nmpN-5oh6A:
undetectable
6nmpP-5oh6A:
1.9		 6nmpN-5oh6A:
16.89
6nmpP-5oh6A:
20.00