SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5oi9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_2
(PROTEASE RETROPEPSIN)		 5oi9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Trichoplax
adhaerens) 		5 / 12 LEU A 343
GLY A 185
ILE A  84
VAL A 115
ILE A  38
 None
 0.89A 2rkgB-5oi9A:
undetectable		 2rkgB-5oi9A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_D_BRLD478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5oi9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Trichoplax
adhaerens) 		4 / 4 ILE A 328
GLN A  49
ILE A  40
LEU A 123
 None
 1.32A 3dzyD-5oi9A:
undetectable		 3dzyD-5oi9A:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_B_NIOB5661_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 5oi9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Trichoplax
adhaerens) 		4 / 8 ILE A 167
ALA A 169
LEU A  45
ALA A  52
 None
 0.85A 3hrdA-5oi9A:
undetectable
3hrdB-5oi9A:
undetectable		 3hrdA-5oi9A:
12.00
3hrdB-5oi9A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 5oi9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Trichoplax
adhaerens) 		5 / 12 ILE A 294
GLY A 255
ALA A 272
ALA A 231
VAL A 230
 None
 1.09A 3jb3A-5oi9A:
undetectable		 3jb3A-5oi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_2
(PROTEASE)		 5oi9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Trichoplax
adhaerens) 		5 / 10 LEU A 343
GLY A 185
ILE A  84
VAL A 115
ILE A  38
 None
 0.94A 3s43B-5oi9A:
undetectable		 3s43B-5oi9A:
25.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFG_B_QMRB1214_1
(CAPITELLA TELETA
ACHBP)		 5oi9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Trichoplax
adhaerens) 		5 / 9 ILE A 286
ILE A 251
VAL A 254
TYR A 229
TYR A 276
 None
 1.47A 4afgA-5oi9A:
0.3
4afgE-5oi9A:
undetectable		 4afgA-5oi9A:
16.06
4afgE-5oi9A:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFG_C_QMRC1214_1
(CAPITELLA TELETA
ACHBP)		 5oi9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Trichoplax
adhaerens) 		5 / 8 VAL A 254
TYR A 229
TYR A 276
ILE A 286
ILE A 251
 None
 1.48A 4afgD-5oi9A:
undetectable
4afgE-5oi9A:
undetectable		 4afgD-5oi9A:
16.06
4afgE-5oi9A:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFG_D_QMRD1214_1
(CAPITELLA TELETA
ACHBP)		 5oi9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Trichoplax
adhaerens) 		5 / 9 VAL A 254
TYR A 229
TYR A 276
ILE A 286
ILE A 251
 None
 1.48A 4afgC-5oi9A:
undetectable
4afgD-5oi9A:
undetectable		 4afgC-5oi9A:
16.06
4afgD-5oi9A:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFG_E_QMRE1214_1
(CAPITELLA TELETA
ACHBP)		 5oi9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Trichoplax
adhaerens) 		5 / 9 VAL A 254
TYR A 229
TYR A 276
ILE A 286
ILE A 251
 None
 1.48A 4afgB-5oi9A:
0.2
4afgC-5oi9A:
0.0		 4afgB-5oi9A:
16.06
4afgC-5oi9A:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_A_ACTA1002_0
(ACTIN, ALPHA
SKELETAL MUSCLE
FORMIN-LIKE PROTEIN
3)		 5oi9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Trichoplax
adhaerens) 		4 / 5 THR A  59
GLN A  54
GLU A  58
THR A  57
 None
 1.36A 4eahA-5oi9A:
undetectable
4eahE-5oi9A:
undetectable
4eahG-5oi9A:
undetectable		 4eahA-5oi9A:
undetectable
4eahE-5oi9A:
undetectable
4eahG-5oi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA302_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 5oi9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Trichoplax
adhaerens) 		4 / 5 TYR A 139
GLN A 323
GLY A 185
SER A 184
 None
 1.31A 4fu8A-5oi9A:
undetectable		 4fu8A-5oi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0R_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 5oi9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Trichoplax
adhaerens) 		5 / 12 VAL A 186
LEU A  74
ILE A  84
LEU A 165
ILE A  38
 None
 1.03A 4y0rA-5oi9A:
undetectable		 4y0rA-5oi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_1
(PROTEASE)		 5oi9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Trichoplax
adhaerens) 		5 / 12 LEU A 343
GLY A 185
ILE A  84
VAL A 115
ILE A  38
 None
 0.80A 5e5jA-5oi9A:
undetectable		 5e5jA-5oi9A:
25.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_1
(PROTEASE)		 5oi9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Trichoplax
adhaerens) 		5 / 12 LEU A 343
GLY A 185
ILE A  84
VAL A 115
ILE A  38
 None
 0.86A 5t8hA-5oi9A:
undetectable		 5t8hA-5oi9A:
25.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_A_TKTA508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 5oi9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Trichoplax
adhaerens) 		4 / 8 ASP A  39
ILE A  38
ARG A 342
ASN A 353
 None
 1.24A 6hisA-5oi9A:
undetectable
6hisB-5oi9A:
undetectable		 6hisA-5oi9A:
18.75
6hisB-5oi9A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_B_TKTB508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 5oi9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Trichoplax
adhaerens) 		4 / 8 ASP A  39
ILE A  38
ARG A 342
ASN A 353
 None
 1.25A 6hisB-5oi9A:
undetectable
6hisC-5oi9A:
undetectable		 6hisB-5oi9A:
18.75
6hisC-5oi9A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_C_TKTC508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 5oi9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Trichoplax
adhaerens) 		4 / 8 ASP A  39
ILE A  38
ARG A 342
ASN A 353
 None
 1.24A 6hisC-5oi9A:
undetectable
6hisD-5oi9A:
undetectable		 6hisC-5oi9A:
18.75
6hisD-5oi9A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_D_TKTD501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 5oi9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Trichoplax
adhaerens) 		4 / 8 ASP A  39
ILE A  38
ARG A 342
ASN A 353
 None
 1.24A 6hisD-5oi9A:
undetectable
6hisE-5oi9A:
undetectable		 6hisD-5oi9A:
18.75
6hisE-5oi9A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_E_TKTE501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 5oi9 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Trichoplax
adhaerens) 		4 / 8 ASN A 353
ASP A  39
ILE A  38
ARG A 342
 None
 1.25A 6hisA-5oi9A:
undetectable
6hisE-5oi9A:
undetectable		 6hisA-5oi9A:
18.75
6hisE-5oi9A:
18.75