SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5oie'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AGM_A_ACRA495_1
(GLUCOAMYLASE-471)		 5oie -
(-) 		5 / 12 ALA A  31
TRP A  40
ASP A  43
TYR A 375
TRP A 381
 GOL  A 501 ( 4.0A)
GOL  A 501 ( 4.0A)
GOL  A 501 (-2.9A)
None
None
 0.99A 1agmA-5oieA:
18.0		 1agmA-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AGM_A_ACRA495_1
(GLUCOAMYLASE-471)		 5oie -
(-) 		5 / 12 ALA A  31
TYR A  36
ASP A  43
TYR A 375
TRP A 381
 GOL  A 501 ( 4.0A)
GOL  A 501 ( 3.7A)
GOL  A 501 (-2.9A)
None
None
 1.00A 1agmA-5oieA:
18.0		 1agmA-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AGM_A_ACRA496_1
(GLUCOAMYLASE-471)		 5oie -
(-) 		5 / 12 ALA A  31
TRP A  40
ASP A  43
TYR A 375
TRP A 381
 GOL  A 501 ( 4.0A)
GOL  A 501 ( 4.0A)
GOL  A 501 (-2.9A)
None
None
 0.99A 1agmA-5oieA:
18.0		 1agmA-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AGM_A_ACRA496_1
(GLUCOAMYLASE-471)		 5oie -
(-) 		5 / 12 ALA A  31
TYR A  36
ASP A  43
TYR A 375
TRP A 381
 GOL  A 501 ( 4.0A)
GOL  A 501 ( 3.7A)
GOL  A 501 (-2.9A)
None
None
 1.00A 1agmA-5oieA:
18.0		 1agmA-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMC_A_SAMA105_0
(MET REPRESSOR)		 5oie -
(-) 		5 / 10 GLY A 220
LEU A 229
GLU A 230
LEU A 199
PRO A 200
 None
 0.91A 1cmcA-5oieA:
undetectable
1cmcB-5oieA:
undetectable		 1cmcA-5oieA:
undetectable
1cmcB-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 5oie -
(-) 		5 / 12 PHE A  46
ILE A 121
LEU A 328
VAL A 383
ILE A 360
 None
 0.99A 1epbB-5oieA:
undetectable		 1epbB-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXV_B_PNNB1001_0
(PENICILLIN ACYLASE)		 5oie -
(-) 		4 / 7 PHE A 324
PHE A 349
ALA A 322
PHE A 254
 None
 1.19A 1fxvA-5oieA:
undetectable
1fxvB-5oieA:
undetectable		 1fxvA-5oieA:
undetectable
1fxvB-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_A_ACRA700_1
(GLUCOAMYLASE)		 5oie -
(-) 		5 / 12 ALA A  31
TYR A  36
ASP A  43
ASN A 183
TYR A 375
 GOL  A 501 ( 4.0A)
GOL  A 501 ( 3.7A)
GOL  A 501 (-2.9A)
None
None
 1.02A 1lf9A-5oieA:
9.1		 1lf9A-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_B_ACRB701_1
(GLUCOAMYLASE)		 5oie -
(-) 		5 / 12 ALA A  31
TRP A  40
ASP A  43
TYR A 375
TRP A 381
 GOL  A 501 ( 4.0A)
GOL  A 501 ( 4.0A)
GOL  A 501 (-2.9A)
None
None
 0.96A 1lf9B-5oieA:
9.2		 1lf9B-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_B_ACRB701_1
(GLUCOAMYLASE)		 5oie -
(-) 		5 / 12 ALA A  31
TYR A  36
ASP A  43
ASN A 183
TYR A 375
 GOL  A 501 ( 4.0A)
GOL  A 501 ( 3.7A)
GOL  A 501 (-2.9A)
None
None
 1.04A 1lf9B-5oieA:
9.2		 1lf9B-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_B_ACRB701_1
(GLUCOAMYLASE)		 5oie -
(-) 		5 / 12 ALA A  31
TYR A  36
ASP A  43
TYR A 375
TRP A 381
 GOL  A 501 ( 4.0A)
GOL  A 501 ( 3.7A)
GOL  A 501 (-2.9A)
None
None
 0.95A 1lf9B-5oieA:
9.2		 1lf9B-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2200_0
(PROTEIN (METHIONINE
REPRESSOR))		 5oie -
(-) 		5 / 12 GLY A 220
LEU A 229
GLU A 230
LEU A 199
PRO A 200
 None
 0.94A 1mj2A-5oieA:
undetectable
1mj2B-5oieA:
undetectable		 1mj2A-5oieA:
undetectable
1mj2B-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC2199_0
(PROTEIN (METHIONINE
REPRESSOR))		 5oie -
(-) 		5 / 12 GLY A 220
LEU A 229
GLU A 230
LEU A 199
PRO A 200
 None
 0.92A 1mj2C-5oieA:
undetectable
1mj2D-5oieA:
undetectable		 1mj2C-5oieA:
undetectable
1mj2D-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_C_SAMC200_0
(METHIONINE REPRESSOR)		 5oie -
(-) 		5 / 12 GLY A 220
LEU A 229
GLU A 230
LEU A 199
PRO A 200
 None
 0.93A 1mjoC-5oieA:
undetectable
1mjoD-5oieA:
undetectable		 1mjoC-5oieA:
undetectable
1mjoD-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_A_SAMA200_0
(METHIONINE REPRESSOR)		 5oie -
(-) 		5 / 11 LEU A 229
GLU A 230
LEU A 199
PRO A 200
GLY A 220
 None
 0.90A 1mjqA-5oieA:
undetectable
1mjqB-5oieA:
undetectable		 1mjqA-5oieA:
undetectable
1mjqB-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_B_SAMB200_0
(METHIONINE REPRESSOR)		 5oie -
(-) 		5 / 11 GLY A 220
LEU A 229
GLU A 230
LEU A 199
PRO A 200
 None
 0.90A 1mjqA-5oieA:
undetectable
1mjqB-5oieA:
undetectable		 1mjqA-5oieA:
undetectable
1mjqB-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_C_SAMC199_0
(METHIONINE REPRESSOR)		 5oie -
(-) 		5 / 10 LEU A 229
GLU A 230
LEU A 199
PRO A 200
GLY A 220
 None
 0.87A 1mjqC-5oieA:
undetectable
1mjqD-5oieA:
undetectable		 1mjqC-5oieA:
undetectable
1mjqD-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_D_SAMD200_0
(METHIONINE REPRESSOR)		 5oie -
(-) 		5 / 12 GLY A 220
LEU A 229
GLU A 230
LEU A 199
PRO A 200
 None
 0.85A 1mjqC-5oieA:
undetectable
1mjqD-5oieA:
undetectable		 1mjqC-5oieA:
undetectable
1mjqD-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_H_SAMH200_0
(METHIONINE REPRESSOR)		 5oie -
(-) 		5 / 10 GLY A 220
LEU A 229
GLU A 230
LEU A 199
PRO A 200
 None
 0.90A 1mjqG-5oieA:
undetectable
1mjqH-5oieA:
undetectable		 1mjqG-5oieA:
undetectable
1mjqH-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_I_SAMI199_0
(METHIONINE REPRESSOR)		 5oie -
(-) 		5 / 11 LEU A 229
GLU A 230
LEU A 199
PRO A 200
GLY A 220
 None
 0.87A 1mjqI-5oieA:
undetectable
1mjqJ-5oieA:
undetectable		 1mjqI-5oieA:
undetectable
1mjqJ-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_J_SAMJ200_0
(METHIONINE REPRESSOR)		 5oie -
(-) 		5 / 12 GLY A 220
LEU A 229
GLU A 230
LEU A 199
PRO A 200
 None
 0.85A 1mjqI-5oieA:
undetectable
1mjqJ-5oieA:
undetectable		 1mjqI-5oieA:
undetectable
1mjqJ-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_A_DVAA6_0
(GRAMICIDIN A)		 5oie -
(-) 		3 / 3 ALA A 439
VAL A 441
TRP A 444
 None
 0.85A 1nt5A-5oieA:
undetectable		 1nt5A-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_B_DVAB6_0
(GRAMICIDIN A)		 5oie -
(-) 		3 / 3 ALA A 439
VAL A 441
TRP A 444
 None
 0.85A 1nt5B-5oieA:
undetectable		 1nt5B-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG1_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 5oie -
(-) 		3 / 3 TRP A 227
VAL A 195
PRO A 196
 None
 0.65A 1rg1A-5oieA:
undetectable		 1rg1A-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RH0_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 5oie -
(-) 		3 / 3 TRP A 227
VAL A 195
PRO A 196
 None
 0.64A 1rh0A-5oieA:
undetectable		 1rh0A-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_B_SAMB2501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 5oie -
(-) 		4 / 7 TYR A  18
GLU A  62
THR A  30
SER A 435
 None
 1.14A 1tv8B-5oieA:
undetectable		 1tv8B-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1301_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 5oie -
(-) 		4 / 6 ARG A 336
LEU A 327
PHE A 324
ALA A 325
 None
 0.96A 1ukbA-5oieA:
undetectable		 1ukbA-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ULV_A_ACRA3000_1
(GLUCODEXTRANASE)		 5oie -
(-) 		5 / 12 ALA A  31
TYR A  36
ASP A  43
ASN A 183
TYR A 375
 GOL  A 501 ( 4.0A)
GOL  A 501 ( 3.7A)
GOL  A 501 (-2.9A)
None
None
 1.07A 1ulvA-5oieA:
9.9		 1ulvA-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ULV_A_ACRA3000_1
(GLUCODEXTRANASE)		 5oie -
(-) 		6 / 12 ALA A  31
TYR A  36
TRP A  40
ASP A  43
TYR A 375
TRP A 381
 GOL  A 501 ( 4.0A)
GOL  A 501 ( 3.7A)
GOL  A 501 ( 4.0A)
GOL  A 501 (-2.9A)
None
None
 0.98A 1ulvA-5oieA:
9.9		 1ulvA-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2434_1
(CHITINASE)		 5oie -
(-) 		3 / 3 TRP A 158
THR A 172
TYR A 174
 None
 1.15A 2a3aB-5oieA:
undetectable		 2a3aB-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA995_1
(GLUCOAMYLASE GLU1)		 5oie -
(-) 		5 / 12 ALA A  31
TRP A  40
ASP A  43
TYR A 375
TRP A 381
 GOL  A 501 ( 4.0A)
GOL  A 501 ( 4.0A)
GOL  A 501 (-2.9A)
None
None
 0.97A 2f6dA-5oieA:
17.4		 2f6dA-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA995_1
(GLUCOAMYLASE GLU1)		 5oie -
(-) 		5 / 12 ALA A  31
TYR A  36
ASP A  43
TYR A 375
TRP A 381
 GOL  A 501 ( 4.0A)
GOL  A 501 ( 3.7A)
GOL  A 501 (-2.9A)
None
None
 1.00A 2f6dA-5oieA:
17.4		 2f6dA-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_A_SCKA901_1
(ACETYLCHOLINESTERASE)		 5oie -
(-) 		4 / 8 TYR A 225
ASP A 182
TYR A 222
TYR A 375
 None
SER  A 507 (-3.3A)
None
None
 1.16A 2ha2A-5oieA:
undetectable		 2ha2A-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_A_SCKA901_1
(ACETYLCHOLINESTERASE)		 5oie -
(-) 		4 / 8 TYR A 225
TRP A  40
TYR A 222
TYR A 375
 None
GOL  A 501 ( 4.0A)
None
None
 1.19A 2ha2A-5oieA:
undetectable		 2ha2A-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_B_SCKB951_1
(ACETYLCHOLINESTERASE)		 5oie -
(-) 		4 / 8 TYR A 225
TRP A  40
TYR A 222
TYR A 375
 None
GOL  A 501 ( 4.0A)
None
None
 1.17A 2ha2B-5oieA:
undetectable		 2ha2B-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 5oie -
(-) 		3 / 3 ASP A 102
ASN A 103
THR A 110
 None
 0.72A 2pymB-5oieA:
undetectable		 2pymB-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7L_A_TESA155_1
(ANDROGEN RECEPTOR)		 5oie -
(-) 		5 / 12 LEU A 404
LEU A 359
GLY A 408
GLN A 411
VAL A 383
 None
 1.44A 2q7lA-5oieA:
undetectable		 2q7lA-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5oie -
(-) 		4 / 7 GLY A 303
THR A 298
GLN A 323
PHE A 388
 None
 1.21A 2qx4A-5oieA:
undetectable
2qx4B-5oieA:
undetectable		 2qx4A-5oieA:
undetectable
2qx4B-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3COT_A_STRA1501_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 5oie -
(-) 		4 / 7 TYR A  88
TYR A 375
TRP A 381
TRP A  40
 SER  A 507 (-4.3A)
None
None
GOL  A 501 ( 4.0A)
 1.04A 3cotA-5oieA:
undetectable		 3cotA-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_B_GJZB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 5oie -
(-) 		4 / 6 ILE A 113
THR A 110
ALA A 104
THR A  97
 None
 0.94A 3mdrB-5oieA:
undetectable		 3mdrB-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_A_SAMA300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5oie -
(-) 		5 / 12 TYR A 375
ALA A 419
GLY A 430
ALA A  32
TRP A 436
 None
None
None
None
GOL  A 501 ( 4.4A)
 1.11A 3ou6A-5oieA:
undetectable		 3ou6A-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5oie -
(-) 		5 / 12 TYR A 375
ALA A 419
GLY A 430
ALA A  32
TRP A 436
 None
None
None
None
GOL  A 501 ( 4.4A)
 1.11A 3ou6B-5oieA:
undetectable		 3ou6B-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_F_FOLF301_1
(FOLATE RECEPTOR
ALPHA)		 5oie -
(-) 		3 / 3 ASP A 307
TRP A  42
SER A 184
 None
GOL  A 501 (-4.7A)
None
 1.08A 4lrhF-5oieA:
undetectable		 4lrhF-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTS_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 5oie -
(-) 		5 / 12 GLY A 358
PHE A 349
GLY A 351
SER A 367
PRO A 361
 None
 1.22A 4rtsA-5oieA:
undetectable		 4rtsA-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E2I_A_DMEA605_1
(ACETYLCHOLINESTERASE)		 5oie -
(-) 		4 / 6 TYR A 225
ASP A 182
TYR A 222
TYR A 375
 None
SER  A 507 (-3.3A)
None
None
 1.14A 5e2iA-5oieA:
undetectable		 5e2iA-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB5_A_010A609_0
(HNL ISOENZYME 5)		 5oie -
(-) 		5 / 11 ALA A 122
ALA A 120
VAL A 265
LEU A 387
TRP A 386
 None
 1.26A 5eb5A-5oieA:
undetectable		 5eb5A-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB5_B_010B607_0
(HNL ISOENZYME 5)		 5oie -
(-) 		5 / 10 ALA A 122
ALA A 120
VAL A 265
LEU A 387
TRP A 386
 None
 1.28A 5eb5B-5oieA:
undetectable		 5eb5B-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_F_SAMF301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 5oie -
(-) 		5 / 12 PRO A 379
GLN A 434
GLY A 430
SER A 431
SER A 214
 None
GOL  A 501 (-3.6A)
None
None
None
 1.13A 5hfjF-5oieA:
undetectable		 5hfjF-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NY7_A_NCAA303_0
(AMIDASE)		 5oie -
(-) 		4 / 6 ARG A 348
GLY A 346
PRO A 347
SER A 364
 None
 1.13A 5ny7A-5oieA:
undetectable		 5ny7A-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA821_0
(GEPHYRIN)		 5oie -
(-) 		3 / 3 ARG A 170
PHE A 290
GLY A 293
 None
 0.69A 6fgdA-5oieA:
undetectable		 6fgdA-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FHW_A_ACRA801_1
(GLUCOAMYLASE P)		 5oie -
(-) 		6 / 12 ALA A  31
TYR A  36
TRP A  40
ASP A  43
TYR A 375
TRP A 381
 GOL  A 501 ( 4.0A)
GOL  A 501 ( 3.7A)
GOL  A 501 ( 4.0A)
GOL  A 501 (-2.9A)
None
None
 1.03A 6fhwA-5oieA:
18.8		 6fhwA-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FHW_B_ACRB801_1
(GLUCOAMYLASE P)		 5oie -
(-) 		6 / 12 ALA A  31
TYR A  36
TRP A  40
ASP A  43
TYR A 375
TRP A 381
 GOL  A 501 ( 4.0A)
GOL  A 501 ( 3.7A)
GOL  A 501 ( 4.0A)
GOL  A 501 (-2.9A)
None
None
 1.03A 6fhwB-5oieA:
19.0		 6fhwB-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5oie -
(-) 		4 / 5 ILE A 360
LEU A 384
ARG A 400
LEU A 328
 None
 0.88A 6nmpN-5oieA:
undetectable
6nmpW-5oieA:
undetectable		 6nmpN-5oieA:
undetectable
6nmpW-5oieA:
undetectable