SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5oj3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5oj3 -
(-) 		5 / 12 GLY A 383
ALA A 380
GLY A 335
ALA A 379
THR A 361
 None
 0.94A 1gtnL-5oj3A:
undetectable
1gtnV-5oj3A:
undetectable		 1gtnL-5oj3A:
undetectable
1gtnV-5oj3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QW6_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5oj3 -
(-) 		3 / 3 ARG A 397
VAL A 377
TRP A 378
 None
 1.24A 1qw6A-5oj3A:
undetectable		 1qw6A-5oj3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QWC_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5oj3 -
(-) 		3 / 3 ARG A 397
VAL A 377
TRP A 378
 None
 1.22A 1qwcA-5oj3A:
undetectable		 1qwcA-5oj3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQ5_A_PAUA6001_0
(PANTOTHENATE KINASE)		 5oj3 -
(-) 		5 / 9 ASP A 278
LYS A 326
GLY A 327
HIS A 280
ASN A 343
 None
 1.42A 1sq5A-5oj3A:
undetectable		 1sq5A-5oj3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQ5_B_PAUB6003_0
(PANTOTHENATE KINASE)		 5oj3 -
(-) 		5 / 10 ASP A 278
LYS A 326
GLY A 327
HIS A 280
ASN A 343
 None
 1.43A 1sq5B-5oj3A:
undetectable		 1sq5B-5oj3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQ5_C_PAUC6002_0
(PANTOTHENATE KINASE)		 5oj3 -
(-) 		5 / 9 ASP A 278
LYS A 326
GLY A 327
HIS A 280
ASN A 343
 None
 1.43A 1sq5C-5oj3A:
undetectable		 1sq5C-5oj3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQ5_D_PAUD6004_0
(PANTOTHENATE KINASE)		 5oj3 -
(-) 		5 / 10 ASP A 278
LYS A 326
GLY A 327
HIS A 280
ASN A 343
 None
 1.42A 1sq5D-5oj3A:
undetectable		 1sq5D-5oj3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_L_TRPL81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5oj3 -
(-) 		5 / 12 GLY A 335
ALA A 379
THR A 361
GLY A 383
ALA A 380
 None
 0.99A 1utdL-5oj3A:
undetectable
1utdM-5oj3A:
undetectable		 1utdL-5oj3A:
undetectable
1utdM-5oj3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5oj3 -
(-) 		5 / 12 GLY A 335
ALA A 379
THR A 361
GLY A 383
ALA A 380
 None
 0.97A 1utdO-5oj3A:
undetectable
1utdP-5oj3A:
undetectable		 1utdO-5oj3A:
undetectable
1utdP-5oj3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5oj3 -
(-) 		5 / 11 GLY A 335
ALA A 379
THR A 361
GLY A 383
ALA A 380
 None
 0.98A 1utdP-5oj3A:
undetectable
1utdQ-5oj3A:
undetectable		 1utdP-5oj3A:
undetectable
1utdQ-5oj3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VAG_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5oj3 -
(-) 		3 / 3 ARG A 397
VAL A 377
TRP A 378
 None
 1.21A 1vagA-5oj3A:
undetectable		 1vagA-5oj3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_1
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 5oj3 -
(-) 		3 / 3 GLY A 196
GLU A 144
ASN A 198
 None
 0.73A 1zq9A-5oj3A:
undetectable		 1zq9A-5oj3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVI_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5oj3 -
(-) 		3 / 3 ARG A 397
VAL A 377
TRP A 378
 None
 1.20A 1zviA-5oj3A:
undetectable		 1zviA-5oj3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_B_ROFB902_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 5oj3 -
(-) 		5 / 12 ASP A 251
LEU A 254
PRO A 305
THR A 295
PHE A 292
 None
 1.31A 3g4lB-5oj3A:
undetectable		 3g4lB-5oj3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 5oj3 -
(-) 		3 / 3 GLY A 392
TRP A 396
VAL A 357
 None
 0.70A 3n62B-5oj3A:
undetectable		 3n62B-5oj3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 5oj3 -
(-) 		3 / 3 GLY A 392
TRP A 396
VAL A 357
 None
 0.70A 3n65B-5oj3A:
undetectable		 3n65B-5oj3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 5oj3 -
(-) 		3 / 3 GLY A 392
TRP A 396
VAL A 357
 None
 0.68A 3n66B-5oj3A:
undetectable		 3n66B-5oj3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5oj3 -
(-) 		4 / 5 GLY A 238
GLY A 239
ASN A 241
GLU A 179
 None
 1.17A 4fglC-5oj3A:
undetectable		 4fglC-5oj3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5oj3 -
(-) 		3 / 3 ARG A 397
VAL A 377
TRP A 378
 None
 1.20A 5fvoA-5oj3A:
undetectable		 5fvoA-5oj3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 5oj3 -
(-) 		4 / 5 GLU A 236
THR A 235
GLU A 179
THR A 193
 None
 1.24A 5hm8A-5oj3A:
undetectable		 5hm8A-5oj3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_C_ADNC501_2
(ADENOSYLHOMOCYSTEINA
SE)		 5oj3 -
(-) 		4 / 5 GLU A 236
THR A 235
GLU A 179
THR A 193
 None
 1.24A 5hm8C-5oj3A:
undetectable		 5hm8C-5oj3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_2
(ADENOSYLHOMOCYSTEINA
SE)		 5oj3 -
(-) 		4 / 5 GLU A 236
THR A 235
GLU A 179
THR A 193
 None
 1.25A 5hm8F-5oj3A:
undetectable		 5hm8F-5oj3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_H_ADNH501_2
(ADENOSYLHOMOCYSTEINA
SE)		 5oj3 -
(-) 		4 / 5 GLU A 236
THR A 235
GLU A 179
THR A 193
 None
 1.25A 5hm8H-5oj3A:
undetectable		 5hm8H-5oj3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 5oj3 -
(-) 		3 / 3 ALA A 407
ASN A 408
LEU A 409
 None
 0.39A 5i1oC-5oj3A:
undetectable		 5i1oC-5oj3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5oj3 -
(-) 		3 / 3 VAL A 357
SER A 389
MET A 386
 None
 0.72A 5ikqA-5oj3A:
undetectable		 5ikqA-5oj3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA609_0
(NADH DEHYDROGENASE,
PUTATIVE)		 5oj3 -
(-) 		3 / 3 VAL A 357
SER A 359
TRP A 396
 None
 1.00A 5jwaA-5oj3A:
undetectable		 5jwaA-5oj3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJE_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 5oj3 -
(-) 		4 / 6 LEU A 218
ILE A 240
THR A 235
MET A 189
 None
 1.23A 5ljeA-5oj3A:
undetectable		 5ljeA-5oj3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_1
(CYTOCHROME P450 3A4)		 5oj3 -
(-) 		5 / 12 PHE A 371
SER A 315
ILE A 314
THR A 361
ALA A 379
 None
 1.15A 5vcgA-5oj3A:
undetectable		 5vcgA-5oj3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_ACTB804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5oj3 -
(-) 		3 / 3 GLY A 392
TRP A 396
VAL A 357
 None
 0.68A 5vuoB-5oj3A:
undetectable		 5vuoB-5oj3A:
undetectable