SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5oji'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_B_DVAB8_0
(GRAMICIDIN A)
5oji DEHYDROGENASE/REDUCT
ASE SDR FAMILY
MEMBER 4

(Caenorhabditis
elegans)
3 / 3 VAL A 193
VAL A 226
TRP A 203
ISN  A 302 (-3.4A)
None
None
0.99A 1av2A-5ojiA:
undetectable
1av2B-5ojiA:
undetectable
1av2A-5ojiA:
5.79
1av2B-5ojiA:
5.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC5_A_NCAA2001_0
(NAD-DEPENDENT
DEACETYLASE)
5oji DEHYDROGENASE/REDUCT
ASE SDR FAMILY
MEMBER 4

(Caenorhabditis
elegans)
4 / 7 ALA A 231
ILE A  22
ASP A 228
ILE A 252
None
NAP  A 301 (-3.5A)
None
None
1.02A 1yc5A-5ojiA:
4.1
1yc5A-5ojiA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COJ_B_GBNB420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)
5oji DEHYDROGENASE/REDUCT
ASE SDR FAMILY
MEMBER 4

(Caenorhabditis
elegans)
5 / 9 TYR A 152
ARG A 259
THR A 172
THR A 166
ALA A 151
None
1.30A 2cojA-5ojiA:
undetectable
2cojB-5ojiA:
undetectable
2cojA-5ojiA:
22.28
2cojB-5ojiA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)
5oji DEHYDROGENASE/REDUCT
ASE SDR FAMILY
MEMBER 4

(Caenorhabditis
elegans)
3 / 3 ASN A  95
HIS A  96
VAL A 119
NAP  A 301 (-2.9A)
None
None
0.83A 3elzB-5ojiA:
undetectable
3elzB-5ojiA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_B_CHDB924_0
(FERROCHELATASE,
MITOCHONDRIAL)
5oji DEHYDROGENASE/REDUCT
ASE SDR FAMILY
MEMBER 4

(Caenorhabditis
elegans)
4 / 7 ARG A 223
PRO A 191
SER A 148
GLY A 254
None
NAP  A 301 (-3.9A)
ISN  A 302 ( 2.2A)
None
1.09A 3hcrB-5ojiA:
3.6
3hcrB-5ojiA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_0
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)
5oji DEHYDROGENASE/REDUCT
ASE SDR FAMILY
MEMBER 4

(Caenorhabditis
elegans)
6 / 12 LEU A  92
ILE A  69
GLN A  75
HIS A  96
ILE A 143
PHE A 145
None
NAP  A 301 (-3.7A)
None
None
None
None
1.25A 4rp8C-5ojiA:
undetectable
4rp8C-5ojiA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)
5oji DEHYDROGENASE/REDUCT
ASE SDR FAMILY
MEMBER 4

(Caenorhabditis
elegans)
5 / 12 ILE A  39
VAL A  93
GLU A 138
ALA A 238
VAL A 234
None
0.91A 5igjA-5ojiA:
undetectable
5igjA-5ojiA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)
5oji DEHYDROGENASE/REDUCT
ASE SDR FAMILY
MEMBER 4

(Caenorhabditis
elegans)
5 / 12 GLY A  23
VAL A  93
ILE A  51
ALA A  50
VAL A  62
None
1.08A 5n0sA-5ojiA:
2.1
5n0sA-5ojiA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)
5oji DEHYDROGENASE/REDUCT
ASE SDR FAMILY
MEMBER 4

(Caenorhabditis
elegans)
5 / 12 GLY A  23
VAL A  93
ILE A  51
ALA A  50
VAL A  62
None
1.10A 5n0wB-5ojiA:
undetectable
5n0wB-5ojiA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)
5oji DEHYDROGENASE/REDUCT
ASE SDR FAMILY
MEMBER 4

(Caenorhabditis
elegans)
5 / 12 GLY A  23
VAL A  93
ILE A  51
ALA A  50
VAL A  62
None
1.12A 5n0xA-5ojiA:
2.1
5n0xA-5ojiA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)
5oji DEHYDROGENASE/REDUCT
ASE SDR FAMILY
MEMBER 4

(Caenorhabditis
elegans)
5 / 12 GLY A  23
VAL A  93
ILE A  51
ALA A  50
VAL A  62
None
1.08A 5n4iA-5ojiA:
2.0
5n4iA-5ojiA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_1
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)
5oji DEHYDROGENASE/REDUCT
ASE SDR FAMILY
MEMBER 4

(Caenorhabditis
elegans)
4 / 7 ILE A  14
GLU A 138
HIS A 134
VAL A 131
None
1.06A 6j20A-5ojiA:
undetectable
6j20A-5ojiA:
18.36