SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ojj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_D_DEXD4999_2
(GLUCOCORTICOID
RECEPTOR)		 5ojj UBIQUITIN-CONJUGATIN
G ENZYME E2 T
(Homo
sapiens) 		4 / 5 LEU A   7
MET A  13
LEU A  14
GLN A  26
 None
 1.00A 1p93D-5ojjA:
undetectable		 1p93D-5ojjA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_E_ZPCE1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5ojj UBIQUITIN-CONJUGATIN
G ENZYME E2 T
(Homo
sapiens) 		4 / 6 GLU A 131
TYR A  75
HIS A 150
PHE A 139
 None
 1.07A 4a97E-5ojjA:
undetectable		 4a97E-5ojjA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5ojj UBIQUITIN-CONJUGATIN
G ENZYME E2 T
(Homo
sapiens) 		4 / 7 GLU A 131
TYR A  75
HIS A 150
PHE A 139
 None
 1.08A 4a97H-5ojjA:
undetectable		 4a97H-5ojjA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GTR_A_ESTA601_2
(ESTROGEN RECEPTOR)		 5ojj UBIQUITIN-CONJUGATIN
G ENZYME E2 T
(Homo
sapiens) 		4 / 5 LEU A  53
LEU A  90
PHE A  70
LEU A 114
 None
 1.03A 5gtrA-5ojjA:
undetectable		 5gtrA-5ojjA:
18.93