SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ojr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_A_KANA558_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)
5ojr -
(-)
4 / 7 SER A 250
ASP A 251
GLU A 217
GLU A 210
None
0.91A 1knyA-5ojrA:
undetectable
1knyB-5ojrA:
undetectable
1knyA-5ojrA:
undetectable
1knyB-5ojrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LW0_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)
5ojr -
(-)
5 / 10 LEU A  93
VAL A  72
TYR A 100
GLY A  73
LEU A 122
None
1.38A 1lw0A-5ojrA:
undetectable
1lw0A-5ojrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8E_B_H4BB903_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)
5ojr -
(-)
3 / 3 ARG A  82
ILE A  64
TRP A  70
None
1.14A 1m8eB-5ojrA:
undetectable
1m8eB-5ojrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)
5ojr -
(-)
3 / 3 ARG A  82
ILE A  64
TRP A  70
None
1.11A 1nodB-5ojrA:
undetectable
1nodB-5ojrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QOM_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)
5ojr -
(-)
3 / 3 ARG A  82
ILE A  64
TRP A  70
None
1.08A 1qomA-5ojrA:
undetectable
1qomA-5ojrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)
5ojr -
(-)
5 / 12 PHE A 232
GLY A 236
SER A 255
HIS A 219
TYR A 206
None
1.47A 1zgyA-5ojrA:
undetectable
1zgyA-5ojrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)
5ojr -
(-)
3 / 3 ARG A  82
ILE A  64
TRP A  70
None
1.09A 2nodB-5ojrA:
undetectable
2nodB-5ojrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E6T_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)
5ojr -
(-)
3 / 3 ARG A  82
ILE A  64
TRP A  70
None
1.10A 3e6tB-5ojrA:
undetectable
3e6tB-5ojrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7I_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)
5ojr -
(-)
3 / 3 ARG A  82
ILE A  64
TRP A  70
None
1.14A 3e7iB-5ojrA:
undetectable
3e7iB-5ojrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)
5ojr -
(-)
3 / 3 ARG A  82
ILE A  64
TRP A  70
None
1.06A 3nw2A-5ojrA:
undetectable
3nw2A-5ojrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)
5ojr -
(-)
3 / 3 ARG A  82
ILE A  64
TRP A  70
None
1.07A 3nw2B-5ojrA:
undetectable
3nw2B-5ojrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_B_ADNB501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))
5ojr -
(-)
4 / 5 GLN A  51
THR A  54
THR A  81
LEU A 335
None
1.04A 4lvcB-5ojrA:
undetectable
4lvcB-5ojrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_B_SALB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
5ojr -
(-)
4 / 7 LEU A 273
TYR A 316
GLY A 288
ALA A 289
None
0.88A 5f1aB-5ojrA:
undetectable
5f1aB-5ojrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JI0_D_BRLD501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
5ojr -
(-)
5 / 12 PHE A 232
GLY A 236
SER A 255
HIS A 219
TYR A 206
None
1.45A 5ji0D-5ojrA:
undetectable
5ji0D-5ojrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OAJ_E_TKTE601_1
()
5ojr -
(-)
4 / 8 CYH A 294
TYR A  44
PHE A 320
ARG A 278
None
1.50A 5oajD-5ojrA:
undetectable
5oajE-5ojrA:
undetectable
5oajD-5ojrA:
undetectable
5oajE-5ojrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAC_C_RFPC3001_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)
5ojr -
(-)
5 / 12 GLN A 108
HIS A 123
SER A 106
ARG A 190
ILE A 147
None
1.41A 5uacC-5ojrA:
1.2
5uacC-5ojrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)
5ojr -
(-)
4 / 5 GLN A  51
THR A  54
THR A  81
LEU A 335
None
1.09A 6aphA-5ojrA:
undetectable
6aphA-5ojrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_A_ADNA502_2
(-)
5ojr -
(-)
4 / 4 GLN A  51
THR A  54
THR A  81
LEU A 335
None
1.10A 6f3mA-5ojrA:
undetectable
6f3mA-5ojrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_C_ADNC502_2
(-)
5ojr -
(-)
4 / 4 GLN A  51
THR A  54
THR A  81
LEU A 335
None
1.09A 6f3mC-5ojrA:
undetectable
6f3mC-5ojrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_2
(-)
5ojr -
(-)
4 / 5 GLN A  51
THR A  54
THR A  81
LEU A 335
None
1.05A 6gbnB-5ojrA:
undetectable
6gbnB-5ojrA:
undetectable