SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ojy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_B_SAMB201_1
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 5ojy TETR FAMILY
TRANSCRIPTION
REGULATOR
(Streptomyces
alboniger) 		4 / 5 PRO A  91
ALA A 141
ASP A 110
ASP A 103
 None
 1.03A 2nyuB-5ojyA:
undetectable		 2nyuB-5ojyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5ojy TETR FAMILY
TRANSCRIPTION
REGULATOR
(Streptomyces
alboniger) 		5 / 11 TYR A 164
ILE A 163
ASP A 103
GLY A 107
ALA A 106
 None
 1.07A 3rukD-5ojyA:
undetectable		 3rukD-5ojyA:
9.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_B_URFB302_1
(URIDINE
PHOSPHORYLASE)		 5ojy TETR FAMILY
TRANSCRIPTION
REGULATOR
(Streptomyces
alboniger) 		4 / 7 THR A 167
GLY A 169
ALA A 171
ILE A 122
 None
None
None
GOL  A 302 ( 4.7A)
 0.95A 4txnB-5ojyA:
undetectable		 4txnB-5ojyA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_C_URFC302_1
(URIDINE
PHOSPHORYLASE)		 5ojy TETR FAMILY
TRANSCRIPTION
REGULATOR
(Streptomyces
alboniger) 		4 / 7 THR A 167
GLY A 169
ALA A 171
ILE A 122
 None
None
None
GOL  A 302 ( 4.7A)
 0.94A 4txnC-5ojyA:
undetectable		 4txnC-5ojyA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_D_URFD302_1
(URIDINE
PHOSPHORYLASE)		 5ojy TETR FAMILY
TRANSCRIPTION
REGULATOR
(Streptomyces
alboniger) 		4 / 7 THR A 167
GLY A 169
ALA A 171
ILE A 122
 None
None
None
GOL  A 302 ( 4.7A)
 0.96A 4txnD-5ojyA:
undetectable		 4txnD-5ojyA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC3_A_486A801_2
(GLUCOCORTICOID
RECEPTOR)		 5ojy TETR FAMILY
TRANSCRIPTION
REGULATOR
(Streptomyces
alboniger) 		4 / 5 LEU A 160
LEU A 156
MET A 237
TYR A 166
 None
 1.25A 5uc3A-5ojyA:
3.3		 5uc3A-5ojyA:
24.21