SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ok8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1A4L_B_DCFB853_2 (ADENOSINE DEAMINASE)	5ok8	LPP20 LIPOPROTEIN (Helicobacter pylori)	4 / 5	LEU A 52 SER A 140 LEU A 137 GLY A 67	None	1.12A	1a4lB-5ok8A: undetectable	1a4lB-5ok8A: 15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BM9_C_SAMC301_0 (CEPHALOSPORIN HYDROXYLASE CMCI)	5ok8	LPP20 LIPOPROTEIN (Helicobacter pylori)	5 / 12	LEU A 137 GLY A 67 ASN A 92 ALA A 89 ALA A 85	None	1.11A	2bm9C-5ok8A: undetectable	2bm9C-5ok8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BM9_E_SAME301_0 (CEPHALOSPORIN HYDROXYLASE CMCI)	5ok8	LPP20 LIPOPROTEIN (Helicobacter pylori)	5 / 12	LEU A 137 GLY A 67 ASN A 92 ALA A 89 ALA A 85	None	1.02A	2bm9E-5ok8A: undetectable	2bm9E-5ok8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F3T_A_IPHA902_0 (PROTEIN ARGONAUTE-2)	5ok8	LPP20 LIPOPROTEIN (Helicobacter pylori)	4 / 6	LEU A 170 LYS A 165 LEU A 132 GLU A 136	None	1.20A	4f3tA-5ok8A: undetectable	4f3tA-5ok8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MM4_A_8PRA603_1 (TRANSPORTER)	5ok8	LPP20 LIPOPROTEIN (Helicobacter pylori)	5 / 12	VAL A 55 ALA A 56 TYR A 58 TYR A 61 ASP A 46	None	1.35A	4mm4A-5ok8A: undetectable	4mm4A-5ok8A: 11.61

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1A4L_B_DCFB853_2","ADENOSINE DEAMINASE","5ok8","LPP20 LIPOPROTEIN","Helicobacter pylori",4,"LEU A  52;SER A 140;LEU A 137;GLY A  67","None","1.12A","1a4lB-5ok8A:undetectable","1a4lB-5ok8A:15.74"],["2BM9_C_SAMC301_0","CEPHALOSPORIN HYDROXYLASE CMCI","5ok8","LPP20 LIPOPROTEIN","Helicobacter pylori",5,"LEU A 137;GLY A  67;ASN A  92;ALA A  89;ALA A  85","None","1.11A","2bm9C-5ok8A:undetectable","2bm9C-5ok8A:undetectable"],["2BM9_E_SAME301_0","CEPHALOSPORIN HYDROXYLASE CMCI","5ok8","LPP20 LIPOPROTEIN","Helicobacter pylori",5,"LEU A 137;GLY A  67;ASN A  92;ALA A  89;ALA A  85","None","1.02A","2bm9E-5ok8A:undetectable","2bm9E-5ok8A:undetectable"],["4F3T_A_IPHA902_0","PROTEIN ARGONAUTE-2","5ok8","LPP20 LIPOPROTEIN","Helicobacter pylori",4,"LEU A 170;LYS A 165;LEU A 132;GLU A 136","None","1.20A","4f3tA-5ok8A:undetectable","4f3tA-5ok8A:undetectable"],["4MM4_A_8PRA603_1","TRANSPORTER","5ok8","LPP20 LIPOPROTEIN","Helicobacter pylori",5,"VAL A  55;ALA A  56;TYR A  58;TYR A  61;ASP A  46","None","1.35A","4mm4A-5ok8A:undetectable","4mm4A-5ok8A:11.61"]]