SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5okd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 5okd CYTOCHROME C1, HEME
PROTEIN,
MITOCHONDRIAL
(Bos
taurus) 		3 / 3 THR D 188
SER D  20
LYS D 202
 None
 0.92A 3aocC-5okdD:
undetectable		 3aocC-5okdD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_A_ACTA500_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 5okd CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL
(Bos
taurus) 		4 / 4 ALA E 176
HIS E 141
HIS E 161
PRO E 175
 FES  E 201 ( 4.9A)
FES  E 201 (-3.8A)
FES  E 201 (-3.4A)
FES  E 201 ( 4.6A)
 1.31A 3mbgA-5okdE:
undetectable		 3mbgA-5okdE:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_C_ACTC900_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 5okd CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL
(Bos
taurus) 		4 / 4 ALA E 176
HIS E 141
HIS E 161
PRO E 175
 FES  E 201 ( 4.9A)
FES  E 201 (-3.8A)
FES  E 201 (-3.4A)
FES  E 201 ( 4.6A)
 1.31A 3mbgC-5okdE:
undetectable		 3mbgC-5okdE:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_C_BEZC1_0
(HEME-BINDING PROTEIN
HUTZ)		 5okd CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL
(Bos
taurus) 		4 / 5 ARG E  99
PHE E  97
PRO E 146
LEU E 135
 None
 1.39A 3tgvC-5okdE:
undetectable		 3tgvC-5okdE:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)		 5okd CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL
(Bos
taurus) 		3 / 3 PRO E 183
TYR E 185
GLY E 196
 None
 0.74A 4g2zA-5okdE:
undetectable		 4g2zA-5okdE:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_A_RBVA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5okd CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL
(Bos
taurus) 		3 / 3 THR E 140
HIS E 122
LEU E 117
 None
 0.76A 5axdA-5okdE:
undetectable		 5axdA-5okdE:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_2
(CDL2.3A)		 5okd CYTOCHROME C1, HEME
PROTEIN,
MITOCHONDRIAL
(Bos
taurus) 		4 / 8 ILE D 164
LEU D 113
ILE D 116
LEU D 169
 None
None
HEC  D 501 (-4.2A)
None
 0.88A 5ieoA-5okdD:
undetectable		 5ieoA-5okdD:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5okd CYTOCHROME C1, HEME
PROTEIN,
MITOCHONDRIAL
(Bos
taurus) 		5 / 12 PHE D 189
LEU D 169
ILE D 164
LEU D  51
TYR D  56
 None
 1.46A 5ycpA-5okdD:
undetectable		 5ycpA-5okdD:
20.93