SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ol1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA508_0
(CHORISMATE SYNTHASE)		 5ol1 DNA POLYMERASE III
SUBUNIT ALPHA,DNA
POLYMERASE III
SUBUNIT ALPHA
(Synechocystis
sp.
PCC
6803) 		4 / 5 LEU A  44
ASP A  17
ALA A  43
ILE A  50
 None
CSO  A  37 ( 3.0A)
None
None
 0.78A 2qhfA-5ol1A:
undetectable		 2qhfA-5ol1A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA451_1
(CYTOCHROME P450
164A2)		 5ol1 DNA POLYMERASE III
SUBUNIT ALPHA,DNA
POLYMERASE III
SUBUNIT ALPHA
(Synechocystis
sp.
PCC
6803) 		5 / 10 LEU A 139
LEU A  28
ILE A  33
ALA A  34
VAL A   4
 None
 1.26A 3r9cA-5ol1A:
undetectable		 3r9cA-5ol1A:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5ol1 DNA POLYMERASE III
SUBUNIT ALPHA,DNA
POLYMERASE III
SUBUNIT ALPHA
(Synechocystis
sp.
PCC
6803) 		6 / 12 ALA A  36
PHE A  26
TYR A 100
ILE A 108
LEU A  28
ALA A  43
 CSO  A  37 ( 3.1A)
None
None
None
None
None
 1.25A 3rukA-5ol1A:
undetectable		 3rukA-5ol1A:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5ol1 DNA POLYMERASE III
SUBUNIT ALPHA,DNA
POLYMERASE III
SUBUNIT ALPHA
(Synechocystis
sp.
PCC
6803) 		6 / 12 ALA A  36
TYR A 100
ILE A 108
LEU A  28
ALA A  43
VAL A  64
 CSO  A  37 ( 3.1A)
None
None
None
None
None
 1.22A 3rukA-5ol1A:
undetectable		 3rukA-5ol1A:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 5ol1 DNA POLYMERASE III
SUBUNIT ALPHA,DNA
POLYMERASE III
SUBUNIT ALPHA
(Synechocystis
sp.
PCC
6803) 		4 / 5 LEU A 117
LEU A 137
LEU A  27
SER A  74
 None
 0.94A 3vhuA-5ol1A:
undetectable		 3vhuA-5ol1A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA205_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 5ol1 DNA POLYMERASE III
SUBUNIT ALPHA,DNA
POLYMERASE III
SUBUNIT ALPHA
(Synechocystis
sp.
PCC
6803) 		5 / 12 PRO A  59
ASN A  30
ALA A  32
GLY A  31
LEU A 139
 None
 1.34A 4oadA-5ol1A:
undetectable		 4oadA-5ol1A:
22.10