SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ol9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_B_MXMB807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5ol9 TRANSCRIPTION
ELONGATION FACTOR,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 12 LEU A 112
ILE A 133
LEU A 134
ALA A  71
LEU A  74
 None
 1.12A 4o1zB-5ol9A:
undetectable		 4o1zB-5ol9A:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1F_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 5ol9 TRANSCRIPTION
ELONGATION FACTOR,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 12 LEU A 115
SER A 125
LEU A  77
ARG A  95
ILE A  99
 None
 1.03A 4x1fA-5ol9A:
undetectable		 4x1fA-5ol9A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1G_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 5ol9 TRANSCRIPTION
ELONGATION FACTOR,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 12 LEU A 115
SER A 125
LEU A  77
ARG A  95
ILE A  99
 None
 1.07A 4x1gA-5ol9A:
undetectable		 4x1gA-5ol9A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5ol9 TRANSCRIPTION
ELONGATION FACTOR,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 5 SER A  72
ALA A  71
HIS A 137
LEU A 134
 None
 1.44A 5dzkb-5ol9A:
undetectable
5dzkp-5ol9A:
undetectable		 5dzkb-5ol9A:
16.97
5dzkp-5ol9A:
3.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Q_BEZQ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5ol9 TRANSCRIPTION
ELONGATION FACTOR,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 5 SER A  72
ALA A  71
HIS A 137
LEU A 134
 None
 1.44A 5dzkc-5ol9A:
undetectable
5dzkq-5ol9A:
undetectable		 5dzkc-5ol9A:
16.97
5dzkq-5ol9A:
3.51