SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ola'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CD2_A_FOLA307_1
(DIHYDROFOLATE
REDUCTASE)		 5ola TRANSCRIPTION
ELONGATION FACTOR,
MITOCHONDRIAL
(Homo
sapiens) 		3 / 3 GLU A 352
ILE A 348
ARG A 293
 None
 0.82A 1cd2A-5olaA:
undetectable		 1cd2A-5olaA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5ola TRANSCRIPTION
ELONGATION FACTOR,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 12 THR A 332
LEU A 344
VAL A 191
PHE A 317
VAL A 300
 None
 1.38A 1q23C-5olaA:
undetectable		 1q23C-5olaA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5ola TRANSCRIPTION
ELONGATION FACTOR,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 11 THR A 332
LEU A 344
VAL A 191
PHE A 317
VAL A 300
 None
 1.40A 1q23I-5olaA:
undetectable		 1q23I-5olaA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_A_NCAA1501_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 5ola TRANSCRIPTION
ELONGATION FACTOR,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 7 PHE A 285
ARG A 293
ALA A 347
ASP A 342
 None
 1.10A 2e5dA-5olaA:
undetectable
2e5dB-5olaA:
undetectable		 2e5dA-5olaA:
18.45
2e5dB-5olaA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_B_NCAB1502_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 5ola TRANSCRIPTION
ELONGATION FACTOR,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 7 ASP A 342
PHE A 285
ARG A 293
ALA A 347
 None
 1.12A 2e5dA-5olaA:
undetectable
2e5dB-5olaA:
undetectable		 2e5dA-5olaA:
18.45
2e5dB-5olaA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_2
(GENOME POLYPROTEIN)		 5ola TRANSCRIPTION
ELONGATION FACTOR,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 4 PHE A 350
TYR A 229
VAL A 300
LEU A 345
 None
 1.33A 3keeD-5olaA:
undetectable		 3keeD-5olaA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		 5ola TRANSCRIPTION
ELONGATION FACTOR,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 8 TYR A 229
ILE A 171
ILE A 173
ILE A 219
 None
 0.88A 3p4wC-5olaA:
undetectable		 3p4wC-5olaA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5ola TRANSCRIPTION
ELONGATION FACTOR,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 10 THR A 332
LEU A 344
VAL A 191
PHE A 317
VAL A 300
 None
 1.44A 3u9fE-5olaA:
undetectable		 3u9fE-5olaA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_H_CLMH221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5ola TRANSCRIPTION
ELONGATION FACTOR,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 12 THR A 332
LEU A 344
VAL A 191
PHE A 317
VAL A 300
 None
 1.43A 3u9fH-5olaA:
undetectable
3u9fI-5olaA:
undetectable		 3u9fH-5olaA:
18.73
3u9fI-5olaA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5ola TRANSCRIPTION
ELONGATION FACTOR,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 10 THR A 332
LEU A 344
VAL A 191
PHE A 317
VAL A 300
 None
 1.45A 3u9fI-5olaA:
undetectable		 3u9fI-5olaA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5ola TRANSCRIPTION
ELONGATION FACTOR,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 10 THR A 332
LEU A 344
VAL A 191
PHE A 317
VAL A 300
 None
 1.43A 3u9fK-5olaA:
undetectable		 3u9fK-5olaA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_P_CLMP221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5ola TRANSCRIPTION
ELONGATION FACTOR,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 9 THR A 332
LEU A 344
VAL A 191
PHE A 317
VAL A 300
 None
 1.49A 3u9fP-5olaA:
undetectable		 3u9fP-5olaA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5C_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 5ola TRANSCRIPTION
ELONGATION FACTOR,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 12 ALA A 347
SER A 172
GLN A 302
ARG A 293
GLY A 296
 None
 1.04A 5m5cB-5olaA:
undetectable		 5m5cB-5olaA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_B_PFLB407_1
(PROTON-GATED ION
CHANNEL)		 5ola TRANSCRIPTION
ELONGATION FACTOR,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 7 TYR A 229
ILE A 171
ILE A 173
ILE A 219
 None
 0.86A 5murB-5olaA:
undetectable		 5murB-5olaA:
17.73