SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5olj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPK_A_ACAA80_1
(PLASMINOGEN)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		4 / 6 ASP A 668
ASN A 699
ASP A 669
TYR A 625
 None
None
None
GOL  A 801 (-4.5A)
 0.99A 1hpkA-5oljA:
undetectable		 1hpkA-5oljA:
7.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1871_0
(FPRA)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		4 / 7 PHE A 283
PRO A 309
ALA A 213
PHE A 211
 None
 1.30A 1lqtA-5oljA:
undetectable		 1lqtA-5oljA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1428_0
(FPRA)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		4 / 7 PHE A 283
PRO A 309
ALA A 213
PHE A 211
 None
 1.29A 1lquA-5oljA:
undetectable		 1lquA-5oljA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_SAMA500_0
(HISTONE
METHYLTRANSFERASE
DOT1L)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		5 / 12 TYR A 123
VAL A 142
PHE A 147
PHE A 156
PHE A 167
 None
 1.14A 1nw3A-5oljA:
undetectable		 1nw3A-5oljA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_B_CHDB1131_0
(FATTY ACID-BINDING
PROTEIN)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		5 / 10 LEU A 579
ASN A 489
ILE A 479
THR A 478
GLN A 569
 None
 1.35A 1tw4B-5oljA:
1.8		 1tw4B-5oljA:
10.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1X70_A_715A801_1
(DIPEPTIDYL PEPTIDASE
IV)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		10 / 12 ARG A 115
GLU A 195
GLU A 196
TYR A 511
VAL A 619
TYR A 625
TYR A 629
ASN A 670
VAL A 671
HIS A 700
 GOL  A 801 ( 4.4A)
GOL  A 801 ( 4.6A)
None
GOL  A 801 (-4.4A)
None
GOL  A 801 (-4.5A)
GOL  A 801 ( 4.1A)
GOL  A 801 ( 3.6A)
None
None
 0.39A 1x70A-5oljA:
40.0		 1x70A-5oljA:
32.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1X70_B_715B801_1
(DIPEPTIDYL PEPTIDASE
IV)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		10 / 12 ARG A 115
GLU A 195
GLU A 196
SER A 593
VAL A 619
TYR A 625
TYR A 629
ASN A 670
VAL A 671
HIS A 700
 GOL  A 801 ( 4.4A)
GOL  A 801 ( 4.6A)
None
GOL  A 801 (-2.5A)
None
GOL  A 801 (-4.5A)
GOL  A 801 ( 4.1A)
GOL  A 801 ( 3.6A)
None
None
 0.40A 1x70B-5oljA:
39.7		 1x70B-5oljA:
32.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		3 / 3 SER A 394
ASP A 542
CYH A 540
 None
 0.99A 2br4E-5oljA:
undetectable		 2br4E-5oljA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JC9_A_ADNA1497_1
(CYTOSOLIC PURINE
5'-NUCLEOTIDASE)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		4 / 7 ARG A 398
ILE A 396
ASN A 489
GLN A 517
 None
 1.20A 2jc9A-5oljA:
2.5		 2jc9A-5oljA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PH9_A_GNTA301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		4 / 7 TRP A 191
GLN A 299
TYR A 277
TYR A 243
 None
 1.28A 2ph9A-5oljA:
undetectable
2ph9B-5oljA:
undetectable		 2ph9A-5oljA:
14.27
2ph9B-5oljA:
14.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_0
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		5 / 12 PHE A 336
ILE A 317
ALA A 291
LEU A 318
LEU A 377
 None
 1.34A 2rctA-5oljA:
undetectable		 2rctA-5oljA:
12.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2RGU_A_356A901_1
(DIPEPTIDYL PEPTIDASE
4)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		10 / 12 GLU A 195
GLU A 196
TRP A 592
SER A 593
TYR A 594
VAL A 619
TYR A 625
TYR A 629
VAL A 671
HIS A 700
 GOL  A 801 ( 4.6A)
None
None
GOL  A 801 (-2.5A)
None
None
GOL  A 801 (-4.5A)
GOL  A 801 ( 4.1A)
None
None
 0.30A 2rguA-5oljA:
39.7		 2rguA-5oljA:
32.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2RGU_A_356A901_1
(DIPEPTIDYL PEPTIDASE
4)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		9 / 12 GLU A 195
GLU A 196
TYR A 511
TRP A 592
SER A 593
TYR A 594
VAL A 619
TYR A 625
TYR A 629
 GOL  A 801 ( 4.6A)
None
GOL  A 801 (-4.4A)
None
GOL  A 801 (-2.5A)
None
None
GOL  A 801 (-4.5A)
GOL  A 801 ( 4.1A)
 0.68A 2rguA-5oljA:
39.7		 2rguA-5oljA:
32.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2RGU_A_356A901_1
(DIPEPTIDYL PEPTIDASE
4)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		5 / 12 TRP A 592
TYR A 597
TYR A 625
VAL A 671
HIS A 700
 None
None
GOL  A 801 (-4.5A)
None
None
 1.04A 2rguA-5oljA:
39.7		 2rguA-5oljA:
32.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2RGU_B_356B902_1
(DIPEPTIDYL PEPTIDASE
4)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		10 / 11 GLU A 195
GLU A 196
TRP A 592
SER A 593
TYR A 594
VAL A 619
TYR A 625
TYR A 629
VAL A 671
HIS A 700
 GOL  A 801 ( 4.6A)
None
None
GOL  A 801 (-2.5A)
None
None
GOL  A 801 (-4.5A)
GOL  A 801 ( 4.1A)
None
None
 0.29A 2rguB-5oljA:
39.8		 2rguB-5oljA:
32.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2RGU_B_356B902_1
(DIPEPTIDYL PEPTIDASE
4)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		8 / 11 GLU A 195
GLU A 196
TYR A 511
TRP A 592
TYR A 594
VAL A 619
TYR A 625
TYR A 629
 GOL  A 801 ( 4.6A)
None
GOL  A 801 (-4.4A)
None
None
None
GOL  A 801 (-4.5A)
GOL  A 801 ( 4.1A)
 0.69A 2rguB-5oljA:
39.8		 2rguB-5oljA:
32.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2RGU_B_356B902_1
(DIPEPTIDYL PEPTIDASE
4)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		5 / 11 TRP A 592
TYR A 597
TYR A 625
VAL A 671
HIS A 700
 None
None
GOL  A 801 (-4.5A)
None
None
 1.02A 2rguB-5oljA:
39.8		 2rguB-5oljA:
32.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1499_1
(CYTOCHROME P450 3A4)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		4 / 7 SER A 602
ILE A 570
ILE A 589
GLY A 545
 None
 0.99A 2v0mB-5oljA:
undetectable		 2v0mB-5oljA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		3 / 3 ARG A 635
ASP A 273
ASN A 300
 None
 0.81A 2zzmA-5oljA:
undetectable		 2zzmA-5oljA:
19.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJM_A_BJMA1_1
(DIPEPTIDYL PEPTIDASE
4)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		12 / 12 ARG A 115
GLU A 195
GLU A 196
TYR A 511
SER A 593
TYR A 594
VAL A 619
TYR A 625
TYR A 629
ASN A 670
VAL A 671
HIS A 700
 GOL  A 801 ( 4.4A)
GOL  A 801 ( 4.6A)
None
GOL  A 801 (-4.4A)
GOL  A 801 (-2.5A)
None
None
GOL  A 801 (-4.5A)
GOL  A 801 ( 4.1A)
GOL  A 801 ( 3.6A)
None
None
 0.42A 3bjmA-5oljA:
39.8		 3bjmA-5oljA:
32.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJM_A_BJMA1_1
(DIPEPTIDYL PEPTIDASE
4)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		5 / 12 GLU A 195
TYR A 511
SER A 593
VAL A 619
VAL A 671
 GOL  A 801 ( 4.6A)
GOL  A 801 (-4.4A)
GOL  A 801 (-2.5A)
None
None
 1.00A 3bjmA-5oljA:
39.8		 3bjmA-5oljA:
32.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJM_A_BJMA1_1
(DIPEPTIDYL PEPTIDASE
4)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		5 / 12 TYR A 597
TYR A 625
ASN A 670
VAL A 671
HIS A 700
 None
GOL  A 801 (-4.5A)
GOL  A 801 ( 3.6A)
None
None
 0.92A 3bjmA-5oljA:
39.8		 3bjmA-5oljA:
32.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJM_B_BJMB2_1
(DIPEPTIDYL PEPTIDASE
4)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		11 / 12 ARG A 115
GLU A 195
GLU A 196
TYR A 511
SER A 593
VAL A 619
TYR A 625
TYR A 629
ASN A 670
VAL A 671
HIS A 700
 GOL  A 801 ( 4.4A)
GOL  A 801 ( 4.6A)
None
GOL  A 801 (-4.4A)
GOL  A 801 (-2.5A)
None
GOL  A 801 (-4.5A)
GOL  A 801 ( 4.1A)
GOL  A 801 ( 3.6A)
None
None
 0.46A 3bjmB-5oljA:
39.8		 3bjmB-5oljA:
32.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		4 / 8 ARG A 119
ASP A 669
GLU A 196
GLU A 194
 None
 1.05A 3dh0A-5oljA:
undetectable		 3dh0A-5oljA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_C_ADNC302_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		5 / 12 TYR A 511
ALA A 617
GLY A 596
ASN A 675
VAL A 671
 GOL  A 801 (-4.4A)
None
None
None
None
 1.20A 3f8wC-5oljA:
2.4		 3f8wC-5oljA:
18.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_A_T22A800_1
(DIPEPTIDYL PEPTIDASE
4)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		11 / 12 ARG A 115
GLU A 195
GLU A 196
SER A 593
TYR A 594
VAL A 619
TYR A 625
TYR A 629
ASN A 670
VAL A 671
HIS A 700
 GOL  A 801 ( 4.4A)
GOL  A 801 ( 4.6A)
None
GOL  A 801 (-2.5A)
None
None
GOL  A 801 (-4.5A)
GOL  A 801 ( 4.1A)
GOL  A 801 ( 3.6A)
None
None
 0.51A 3g0bA-5oljA:
40.2		 3g0bA-5oljA:
32.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_A_T22A800_1
(DIPEPTIDYL PEPTIDASE
4)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		10 / 12 ARG A 115
GLU A 195
GLU A 196
TYR A 511
TYR A 594
VAL A 619
TYR A 625
TYR A 629
ASN A 670
HIS A 700
 GOL  A 801 ( 4.4A)
GOL  A 801 ( 4.6A)
None
GOL  A 801 (-4.4A)
None
None
GOL  A 801 (-4.5A)
GOL  A 801 ( 4.1A)
GOL  A 801 ( 3.6A)
None
 0.64A 3g0bA-5oljA:
40.2		 3g0bA-5oljA:
32.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_A_T22A800_1
(DIPEPTIDYL PEPTIDASE
4)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		6 / 12 SER A 593
TYR A 597
TYR A 625
ASN A 670
VAL A 671
HIS A 700
 GOL  A 801 (-2.5A)
None
GOL  A 801 (-4.5A)
GOL  A 801 ( 3.6A)
None
None
 1.15A 3g0bA-5oljA:
40.2		 3g0bA-5oljA:
32.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_B_T22B800_1
(DIPEPTIDYL PEPTIDASE
4)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		11 / 12 ARG A 115
GLU A 195
GLU A 196
SER A 593
TYR A 594
VAL A 619
TYR A 625
TYR A 629
ASN A 670
VAL A 671
HIS A 700
 GOL  A 801 ( 4.4A)
GOL  A 801 ( 4.6A)
None
GOL  A 801 (-2.5A)
None
None
GOL  A 801 (-4.5A)
GOL  A 801 ( 4.1A)
GOL  A 801 ( 3.6A)
None
None
 0.52A 3g0bB-5oljA:
39.8		 3g0bB-5oljA:
32.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_B_T22B800_1
(DIPEPTIDYL PEPTIDASE
4)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		10 / 12 ARG A 115
GLU A 195
GLU A 196
TYR A 511
TYR A 594
VAL A 619
TYR A 625
TYR A 629
ASN A 670
HIS A 700
 GOL  A 801 ( 4.4A)
GOL  A 801 ( 4.6A)
None
GOL  A 801 (-4.4A)
None
None
GOL  A 801 (-4.5A)
GOL  A 801 ( 4.1A)
GOL  A 801 ( 3.6A)
None
 0.64A 3g0bB-5oljA:
39.8		 3g0bB-5oljA:
32.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_B_T22B800_1
(DIPEPTIDYL PEPTIDASE
4)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		6 / 12 SER A 593
TYR A 597
TYR A 625
ASN A 670
VAL A 671
HIS A 700
 GOL  A 801 (-2.5A)
None
GOL  A 801 (-4.5A)
GOL  A 801 ( 3.6A)
None
None
 1.17A 3g0bB-5oljA:
39.8		 3g0bB-5oljA:
32.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_C_T22C800_1
(DIPEPTIDYL PEPTIDASE
4)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		11 / 12 ARG A 115
GLU A 195
GLU A 196
SER A 593
TYR A 594
VAL A 619
TYR A 625
TYR A 629
ASN A 670
VAL A 671
HIS A 700
 GOL  A 801 ( 4.4A)
GOL  A 801 ( 4.6A)
None
GOL  A 801 (-2.5A)
None
None
GOL  A 801 (-4.5A)
GOL  A 801 ( 4.1A)
GOL  A 801 ( 3.6A)
None
None
 0.54A 3g0bC-5oljA:
40.3		 3g0bC-5oljA:
32.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_C_T22C800_1
(DIPEPTIDYL PEPTIDASE
4)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		9 / 12 ARG A 115
GLU A 195
GLU A 196
TYR A 511
TYR A 594
VAL A 619
TYR A 625
TYR A 629
ASN A 670
 GOL  A 801 ( 4.4A)
GOL  A 801 ( 4.6A)
None
GOL  A 801 (-4.4A)
None
None
GOL  A 801 (-4.5A)
GOL  A 801 ( 4.1A)
GOL  A 801 ( 3.6A)
 0.67A 3g0bC-5oljA:
40.3		 3g0bC-5oljA:
32.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_C_T22C800_1
(DIPEPTIDYL PEPTIDASE
4)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		6 / 12 SER A 593
TYR A 597
TYR A 625
ASN A 670
VAL A 671
HIS A 700
 GOL  A 801 (-2.5A)
None
GOL  A 801 (-4.5A)
GOL  A 801 ( 3.6A)
None
None
 1.17A 3g0bC-5oljA:
40.3		 3g0bC-5oljA:
32.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_D_T22D800_1
(DIPEPTIDYL PEPTIDASE
4)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		11 / 12 ARG A 115
GLU A 195
GLU A 196
SER A 593
TYR A 594
VAL A 619
TYR A 625
TYR A 629
ASN A 670
VAL A 671
HIS A 700
 GOL  A 801 ( 4.4A)
GOL  A 801 ( 4.6A)
None
GOL  A 801 (-2.5A)
None
None
GOL  A 801 (-4.5A)
GOL  A 801 ( 4.1A)
GOL  A 801 ( 3.6A)
None
None
 0.52A 3g0bD-5oljA:
40.1		 3g0bD-5oljA:
32.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_D_T22D800_1
(DIPEPTIDYL PEPTIDASE
4)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		10 / 12 ARG A 115
GLU A 195
GLU A 196
TYR A 511
TYR A 594
VAL A 619
TYR A 625
TYR A 629
ASN A 670
HIS A 700
 GOL  A 801 ( 4.4A)
GOL  A 801 ( 4.6A)
None
GOL  A 801 (-4.4A)
None
None
GOL  A 801 (-4.5A)
GOL  A 801 ( 4.1A)
GOL  A 801 ( 3.6A)
None
 0.63A 3g0bD-5oljA:
40.1		 3g0bD-5oljA:
32.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_D_T22D800_1
(DIPEPTIDYL PEPTIDASE
4)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		6 / 12 SER A 593
TYR A 597
TYR A 625
ASN A 670
VAL A 671
HIS A 700
 GOL  A 801 (-2.5A)
None
GOL  A 801 (-4.5A)
GOL  A 801 ( 3.6A)
None
None
 1.18A 3g0bD-5oljA:
40.1		 3g0bD-5oljA:
32.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_1
(O-METHYLTRANSFERASE)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		3 / 3 ASP A 208
PHE A 283
SER A 148
 None
 0.86A 3i5uB-5oljA:
undetectable		 3i5uB-5oljA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG801_0
(GLUTAMATE RECEPTOR 2)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		3 / 3 PRO A 309
SER A 206
ASN A 259
 None
 0.90A 3lslG-5oljA:
undetectable		 3lslG-5oljA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_1
(CYTOCHROME P450 3A4)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		5 / 12 LEU A 600
THR A 546
ILE A 614
ALA A 612
ILE A 587
 None
 1.08A 3nxuB-5oljA:
undetectable		 3nxuB-5oljA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_A_SAMA300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		5 / 12 LEU A 603
ALA A 615
GLY A 591
GLY A 613
ALA A 617
 None
 0.95A 3ou6A-5oljA:
undetectable		 3ou6A-5oljA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		5 / 12 LEU A 603
ALA A 615
GLY A 591
GLY A 613
ALA A 617
 None
 0.94A 3ou6B-5oljA:
undetectable		 3ou6B-5oljA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		3 / 3 TYR A  69
GLY A  51
ASP A  50
 None
 0.65A 3ou6C-5oljA:
undetectable		 3ou6C-5oljA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_A_SALA404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		4 / 7 ALA A 352
ARG A 549
ALA A 391
ARG A 398
 None
 1.11A 3twpA-5oljA:
2.1		 3twpA-5oljA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_0
(MNMC2)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		5 / 12 TYR A 427
GLY A 407
ALA A 343
PHE A 387
LEU A 377
 None
 1.06A 3vywC-5oljA:
undetectable		 3vywC-5oljA:
18.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W2T_A_LF7A801_1
(DIPEPTIDYL PEPTIDASE
4)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		12 / 12 ARG A 115
GLU A 195
GLU A 196
TYR A 511
SER A 593
TYR A 594
VAL A 619
TYR A 625
TYR A 629
ASN A 670
VAL A 671
HIS A 700
 GOL  A 801 ( 4.4A)
GOL  A 801 ( 4.6A)
None
GOL  A 801 (-4.4A)
GOL  A 801 (-2.5A)
None
None
GOL  A 801 (-4.5A)
GOL  A 801 ( 4.1A)
GOL  A 801 ( 3.6A)
None
None
 0.38A 3w2tA-5oljA:
39.6		 3w2tA-5oljA:
32.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W2T_A_LF7A801_1
(DIPEPTIDYL PEPTIDASE
4)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		5 / 12 GLU A 195
TYR A 511
SER A 593
TYR A 625
VAL A 671
 GOL  A 801 ( 4.6A)
GOL  A 801 (-4.4A)
GOL  A 801 (-2.5A)
GOL  A 801 (-4.5A)
None
 1.08A 3w2tA-5oljA:
39.6		 3w2tA-5oljA:
32.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W2T_A_LF7A801_1
(DIPEPTIDYL PEPTIDASE
4)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		5 / 12 GLU A 196
TYR A 511
SER A 593
VAL A 619
VAL A 671
 None
GOL  A 801 (-4.4A)
GOL  A 801 (-2.5A)
None
None
 1.00A 3w2tA-5oljA:
39.6		 3w2tA-5oljA:
32.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W2T_A_LF7A801_1
(DIPEPTIDYL PEPTIDASE
4)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		6 / 12 SER A 593
TYR A 597
TYR A 625
ASN A 670
VAL A 671
HIS A 700
 GOL  A 801 (-2.5A)
None
GOL  A 801 (-4.5A)
GOL  A 801 ( 3.6A)
None
None
 1.20A 3w2tA-5oljA:
39.6		 3w2tA-5oljA:
32.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W2T_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		12 / 12 ARG A 115
GLU A 195
GLU A 196
TYR A 511
SER A 593
TYR A 594
VAL A 619
TYR A 625
TYR A 629
ASN A 670
VAL A 671
HIS A 700
 GOL  A 801 ( 4.4A)
GOL  A 801 ( 4.6A)
None
GOL  A 801 (-4.4A)
GOL  A 801 (-2.5A)
None
None
GOL  A 801 (-4.5A)
GOL  A 801 ( 4.1A)
GOL  A 801 ( 3.6A)
None
None
 0.38A 3w2tB-5oljA:
39.9		 3w2tB-5oljA:
32.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W2T_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		5 / 12 GLU A 196
TYR A 511
SER A 593
VAL A 619
VAL A 671
 None
GOL  A 801 (-4.4A)
GOL  A 801 (-2.5A)
None
None
 1.01A 3w2tB-5oljA:
39.9		 3w2tB-5oljA:
32.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W2T_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		6 / 12 SER A 593
TYR A 597
TYR A 625
ASN A 670
VAL A 671
HIS A 700
 GOL  A 801 (-2.5A)
None
GOL  A 801 (-4.5A)
GOL  A 801 ( 3.6A)
None
None
 1.20A 3w2tB-5oljA:
39.9		 3w2tB-5oljA:
32.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR2_A_PARA1609_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		3 / 3 TYR A 125
ARG A  83
SER A  80
 None
 1.15A 4dr2I-5oljA:
undetectable
4dr2J-5oljA:
undetectable		 4dr2I-5oljA:
12.50
4dr2J-5oljA:
9.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EOH_B_TEPB402_1
(PYRIDOXAL KINASE)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		4 / 5 SER A 647
TYR A 644
VAL A 619
ASP A 621
 None
 1.50A 4eohB-5oljA:
undetectable		 4eohB-5oljA:
17.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FFW_A_715A801_1
(DIPEPTIDYL PEPTIDASE
4)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		11 / 12 ARG A 115
GLU A 195
GLU A 196
GLY A 198
TYR A 511
SER A 593
VAL A 619
TYR A 625
ASN A 670
VAL A 671
HIS A 700
 GOL  A 801 ( 4.4A)
GOL  A 801 ( 4.6A)
None
None
GOL  A 801 (-4.4A)
GOL  A 801 (-2.5A)
None
GOL  A 801 (-4.5A)
GOL  A 801 ( 3.6A)
None
None
 0.57A 4ffwA-5oljA:
39.2		 4ffwA-5oljA:
32.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FFW_A_715A801_1
(DIPEPTIDYL PEPTIDASE
4)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		6 / 12 GLU A 196
GLY A 198
TYR A 511
SER A 593
VAL A 619
VAL A 671
 None
None
GOL  A 801 (-4.4A)
GOL  A 801 (-2.5A)
None
None
 1.29A 4ffwA-5oljA:
39.2		 4ffwA-5oljA:
32.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FFW_B_715B801_1
(DIPEPTIDYL PEPTIDASE
4)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		11 / 12 ARG A 115
GLU A 195
GLU A 196
GLY A 198
TYR A 511
SER A 593
VAL A 619
TYR A 625
TYR A 629
VAL A 671
HIS A 700
 GOL  A 801 ( 4.4A)
GOL  A 801 ( 4.6A)
None
None
GOL  A 801 (-4.4A)
GOL  A 801 (-2.5A)
None
GOL  A 801 (-4.5A)
GOL  A 801 ( 4.1A)
None
None
 0.62A 4ffwB-5oljA:
39.1		 4ffwB-5oljA:
32.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_C_SVRC301_1
(NUCLEOCAPSID PROTEIN)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		4 / 8 ARG A 544
MET A 508
PHE A 610
ILE A 570
 None
 1.00A 4j4vC-5oljA:
undetectable		 4j4vC-5oljA:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM8_A_RFXA603_1
(TRANSPORTER)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		5 / 12 TYR A 511
GLY A 562
SER A 593
GLY A 596
ASP A 542
 GOL  A 801 (-4.4A)
None
GOL  A 801 (-2.5A)
None
None
 1.16A 4mm8A-5oljA:
undetectable		 4mm8A-5oljA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_A_29EA603_1
(TRANSPORTER)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		5 / 10 TYR A 597
TYR A 511
GLY A 562
SER A 593
GLY A 596
 None
GOL  A 801 (-4.4A)
None
GOL  A 801 (-2.5A)
None
 1.17A 4mmdA-5oljA:
undetectable		 4mmdA-5oljA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		5 / 9 ALA A 573
THR A 574
ALA A 572
GLY A 608
GLY A 606
 None
 1.19A 4qwuK-5oljA:
undetectable
4qwuL-5oljA:
undetectable		 4qwuK-5oljA:
14.72
4qwuL-5oljA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		5 / 9 ALA A 573
THR A 574
ALA A 572
GLY A 608
GLY A 606
 None
 1.15A 4qwuY-5oljA:
undetectable
4qwuZ-5oljA:
undetectable		 4qwuY-5oljA:
14.72
4qwuZ-5oljA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDC_A_DEXA1778_2
(GLUCOCORTICOID
RECEPTOR)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		3 / 3 MET A 304
GLN A 299
TYR A 277
 None
 0.86A 4udcA-5oljA:
undetectable		 4udcA-5oljA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0P_A_TE4A201_1
(BETA-LACTOGLOBULIN)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		5 / 12 LEU A 312
VAL A 307
LEU A 202
ILE A 281
VAL A 253
 None
 0.82A 4y0pA-5oljA:
undetectable		 4y0pA-5oljA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_N_EVPN2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		4 / 6 SER A 566
GLU A 565
GLY A 658
GLY A 613
 None
 0.77A 5cdnR-5oljA:
undetectable
5cdnS-5oljA:
3.5		 5cdnR-5oljA:
21.39
5cdnS-5oljA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_2
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		4 / 5 PHE A 498
HIS A 503
LEU A 579
PRO A 495
 None
 1.45A 5csyB-5oljA:
undetectable		 5csyB-5oljA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_X_BEZX801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		4 / 5 ARG A 365
ILE A 403
GLY A 379
ILE A 367
 None
 0.85A 5dzki-5oljA:
undetectable
5dzkj-5oljA:
undetectable
5dzkx-5oljA:
undetectable		 5dzki-5oljA:
14.05
5dzkj-5oljA:
14.05
5dzkx-5oljA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERS_A_ACTA803_0
(GEPHYRIN)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		3 / 3 THR A 441
ALA A  38
ASN A 460
 None
 0.59A 5ersA-5oljA:
3.0		 5ersA-5oljA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGC_B_TA1B601_1
(TUBULIN BETA CHAIN)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		5 / 12 ASP A 275
LEU A 202
SER A 627
PHE A 197
LEU A 295
 None
 1.27A 5ogcB-5oljA:
3.2		 5ogcB-5oljA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B1E_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		12 / 12 ARG A 115
GLU A 195
GLU A 196
TYR A 511
SER A 593
TYR A 594
VAL A 619
TYR A 625
TYR A 629
ASN A 670
VAL A 671
HIS A 700
 GOL  A 801 ( 4.4A)
GOL  A 801 ( 4.6A)
None
GOL  A 801 (-4.4A)
GOL  A 801 (-2.5A)
None
None
GOL  A 801 (-4.5A)
GOL  A 801 ( 4.1A)
GOL  A 801 ( 3.6A)
None
None
 0.39A 6b1eB-5oljA:
39.8		 6b1eB-5oljA:
32.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B1E_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		5 / 12 GLU A 196
TYR A 511
SER A 593
VAL A 619
VAL A 671
 None
GOL  A 801 (-4.4A)
GOL  A 801 (-2.5A)
None
None
 1.02A 6b1eB-5oljA:
39.8		 6b1eB-5oljA:
32.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B1E_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		5 / 12 TYR A 597
TYR A 625
ASN A 670
VAL A 671
HIS A 700
 None
GOL  A 801 (-4.5A)
GOL  A 801 ( 3.6A)
None
None
 0.94A 6b1eB-5oljA:
39.8		 6b1eB-5oljA:
32.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CGD_A_AKNA600_1
(BIFUNCTIONAL AAC/APH)		 5olj DIPEPTIDYL PEPTIDASE
IV
(Porphyromonas
gingivalis) 		5 / 10 GLY A 547
ASP A 329
ASP A 327
GLU A 195
VAL A 628
 None
None
None
GOL  A 801 ( 4.6A)
None
 1.32A 6cgdA-5oljA:
undetectable		 6cgdA-5oljA:
8.44