SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5olp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Y_B_MK1B524_1
(PROTEIN (PROTEASE))		 5olp PECTATE LYASE
(Bacteroides
thetaiotaomicron) 		5 / 11 VAL A 337
ILE A 350
GLY A 390
THR A 368
ILE A 366
 None
 0.87A 1c6yA-5olpA:
undetectable		 1c6yA-5olpA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5olp PECTATE LYASE
(Bacteroides
thetaiotaomicron) 		4 / 8 GLY A 409
THR A 339
THR A 368
ILE A 366
 None
 0.74A 1c9sI-5olpA:
undetectable
1c9sJ-5olpA:
undetectable		 1c9sI-5olpA:
10.47
1c9sJ-5olpA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5olp PECTATE LYASE
(Bacteroides
thetaiotaomicron) 		4 / 8 GLY A 409
THR A 339
THR A 368
ILE A 366
 None
 0.77A 1c9sU-5olpA:
undetectable
1c9sV-5olpA:
undetectable		 1c9sU-5olpA:
10.47
1c9sV-5olpA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_B_DVAB6_0
(GRAMICIDIN A)		 5olp PECTATE LYASE
(Bacteroides
thetaiotaomicron) 		4 / 4 VAL A  80
TRP A  86
ALA A  83
VAL A  81
 None
 1.32A 1gmkA-5olpA:
undetectable
1gmkB-5olpA:
undetectable		 1gmkA-5olpA:
8.80
1gmkB-5olpA:
8.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_D_DVAD6_0
(GRAMICIDIN A)		 5olp PECTATE LYASE
(Bacteroides
thetaiotaomicron) 		4 / 4 VAL A  80
TRP A  86
ALA A  83
VAL A  81
 None
 1.48A 1gmkC-5olpA:
undetectable
1gmkD-5olpA:
undetectable		 1gmkC-5olpA:
8.80
1gmkD-5olpA:
8.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5olp PECTATE LYASE
(Bacteroides
thetaiotaomicron) 		4 / 7 GLY A 409
THR A 339
THR A 368
ILE A 366
 None
 0.72A 1gtnA-5olpA:
undetectable
1gtnK-5olpA:
undetectable		 1gtnA-5olpA:
10.47
1gtnK-5olpA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5olp PECTATE LYASE
(Bacteroides
thetaiotaomicron) 		4 / 7 GLY A 409
THR A 339
THR A 368
ILE A 366
 None
 0.74A 1gtnC-5olpA:
undetectable
1gtnD-5olpA:
undetectable		 1gtnC-5olpA:
10.47
1gtnD-5olpA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5olp PECTATE LYASE
(Bacteroides
thetaiotaomicron) 		4 / 6 GLY A 409
THR A 339
THR A 368
ILE A 366
 None
 0.69A 1gtnD-5olpA:
undetectable
1gtnE-5olpA:
undetectable		 1gtnD-5olpA:
10.47
1gtnE-5olpA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5olp PECTATE LYASE
(Bacteroides
thetaiotaomicron) 		4 / 8 GLY A 409
THR A 339
THR A 368
ILE A 366
 None
 0.73A 1gtnE-5olpA:
undetectable
1gtnF-5olpA:
undetectable		 1gtnE-5olpA:
10.47
1gtnF-5olpA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5olp PECTATE LYASE
(Bacteroides
thetaiotaomicron) 		4 / 7 GLY A 409
THR A 339
THR A 368
ILE A 366
 None
 0.74A 1gtnF-5olpA:
undetectable
1gtnG-5olpA:
undetectable		 1gtnF-5olpA:
10.47
1gtnG-5olpA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5olp PECTATE LYASE
(Bacteroides
thetaiotaomicron) 		4 / 8 GLY A 409
THR A 339
THR A 368
ILE A 366
 None
 0.66A 1gtnI-5olpA:
undetectable
1gtnJ-5olpA:
undetectable		 1gtnI-5olpA:
10.47
1gtnJ-5olpA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5olp PECTATE LYASE
(Bacteroides
thetaiotaomicron) 		4 / 7 GLY A 409
THR A 339
THR A 368
ILE A 366
 None
 0.69A 1gtnJ-5olpA:
undetectable
1gtnK-5olpA:
undetectable		 1gtnJ-5olpA:
10.47
1gtnK-5olpA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RKY_A_CUA801_0
(LYSYL OXIDASE)		 5olp PECTATE LYASE
(Bacteroides
thetaiotaomicron) 		3 / 3 HIS A 204
HIS A 201
HIS A 227
 None
 0.68A 1rkyA-5olpA:
undetectable		 1rkyA-5olpA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_I_TRPI81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5olp PECTATE LYASE
(Bacteroides
thetaiotaomicron) 		4 / 8 GLY A 409
THR A 339
THR A 368
ILE A 366
 None
 0.71A 1utdI-5olpA:
undetectable
1utdJ-5olpA:
undetectable		 1utdI-5olpA:
10.47
1utdJ-5olpA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_A_ACTA294_0
(GLYCINE
N-METHYLTRANSFERASE)		 5olp PECTATE LYASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ILE A 193
LEU A 198
ALA A 172
GLU A 175
 None
 1.04A 1xvaA-5olpA:
undetectable
1xvaB-5olpA:
undetectable		 1xvaA-5olpA:
20.18
1xvaB-5olpA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_D_NCAD510_0
(NAD-DEPENDENT
DEACETYLASE 2)		 5olp PECTATE LYASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ALA A 272
PHE A 266
ILE A 226
ASP A 252
 None
 1.12A 1yc2D-5olpA:
undetectable		 1yc2D-5olpA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9G_A_TOPA1159_1
(DIHYDROFOLATE
REDUCTASE)		 5olp PECTATE LYASE
(Bacteroides
thetaiotaomicron) 		5 / 10 ALA A  67
VAL A  91
SER A 147
ILE A 146
PHE A  93
 None
 1.11A 2w9gA-5olpA:
undetectable		 2w9gA-5olpA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRE_X_TOPX300_1
(DIHYDROFOLATE
REDUCTASE)		 5olp PECTATE LYASE
(Bacteroides
thetaiotaomicron) 		5 / 9 ALA A  67
VAL A  91
SER A 147
ILE A 146
PHE A  93
 None
 1.13A 3freX-5olpA:
undetectable		 3freX-5olpA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ITA_D_AICD501_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACC)		 5olp PECTATE LYASE
(Bacteroides
thetaiotaomicron) 		3 / 3 PRO A  41
PHE A  45
ALA A  74
 None
 0.69A 3itaD-5olpA:
undetectable		 3itaD-5olpA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_0
(2'-O-METHYL
TRANSFERASE)		 5olp PECTATE LYASE
(Bacteroides
thetaiotaomicron) 		5 / 12 SER A 133
PRO A  90
GLY A  89
LEU A 198
ASN A 131
 None
 1.36A 3r24A-5olpA:
undetectable		 3r24A-5olpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA502_0
(RNA POLYMERASE
3D-POL)		 5olp PECTATE LYASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A 419
LYS A 444
LYS A 421
 None
 1.39A 4k50A-5olpA:
undetectable		 4k50A-5olpA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE502_0
(RNA POLYMERASE
3D-POL)		 5olp PECTATE LYASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A 419
LYS A 444
LYS A 421
 None
 1.39A 4k50E-5olpA:
undetectable		 4k50E-5olpA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI506_0
(RNA POLYMERASE
3D-POL)		 5olp PECTATE LYASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A 419
LYS A 444
LYS A 421
 None
 1.39A 4k50I-5olpA:
undetectable		 4k50I-5olpA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNX_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 5olp PECTATE LYASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 252
GLU A 254
LEU A 198
SER A 123
LEU A 173
 None
 1.28A 5hnxB-5olpA:
undetectable		 5hnxB-5olpA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5olp PECTATE LYASE
(Bacteroides
thetaiotaomicron) 		4 / 8 SER A 133
ARG A 207
VAL A 120
PHE A 139
 None
 1.35A 5uo7A-5olpA:
undetectable
5uo7B-5olpA:
undetectable		 5uo7A-5olpA:
20.44
5uo7B-5olpA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5olp PECTATE LYASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 387
ILE A 388
ILE A 420
TYR A 405
ILE A 350
 None
 1.00A 5y2tB-5olpA:
undetectable		 5y2tB-5olpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5olp PECTATE LYASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 387
ILE A 420
TYR A 405
LEU A 364
ILE A 350
 None
 1.08A 5y2tB-5olpA:
undetectable		 5y2tB-5olpA:
undetectable