SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5omc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_D_ADND1504_1
(CLASS B ACID
PHOSPHATASE)		 5omc REPLICATION FACTOR A
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 8 PHE A  15
LEU A 120
ASP A  52
THR A 131
 None
 1.10A 1rmtD-5omcA:
undetectable		 1rmtD-5omcA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_1
(HEMK PROTEIN)		 5omc REPLICATION FACTOR A
PROTEIN 1
(Saccharomyces
cerevisiae) 		3 / 3 ASP A  10
PHE A  15
ASN A  23
 None
 0.88A 1sg9B-5omcA:
undetectable		 1sg9B-5omcA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_2
(RETINOIC ACID
RECEPTOR, BETA)		 5omc REPLICATION FACTOR A
PROTEIN 1
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 120
PHE A  11
ARG A  76
 None
 0.73A 1xdkF-5omcA:
undetectable		 1xdkF-5omcA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM201_1
(PROTEIN S100-A4)		 5omc REPLICATION FACTOR A
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 7 GLY A  27
PHE A 119
PHE A  11
GLY A   9
 None
 0.88A 3ko0M-5omcA:
undetectable
3ko0P-5omcA:
undetectable		 3ko0M-5omcA:
16.67
3ko0P-5omcA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP201_1
(PROTEIN S100-A4)		 5omc REPLICATION FACTOR A
PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 7 PHE A  11
GLY A   9
GLY A  27
PHE A 119
 None
 0.82A 3ko0M-5omcA:
undetectable
3ko0P-5omcA:
undetectable		 3ko0M-5omcA:
16.67
3ko0P-5omcA:
16.67