SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5onu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1873_0
(FPRA)		 5onu OUTER MEMBRANE
PROTEIN OMPU
(Vibrio
cholerae) 		3 / 3 ASP A 135
ASP A 163
LYS A 181
 None
GOL  A 403 (-3.0A)
None
 1.08A 1lqtB-5onuA:
undetectable		 1lqtB-5onuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1430_0
(FPRA)		 5onu OUTER MEMBRANE
PROTEIN OMPU
(Vibrio
cholerae) 		3 / 3 ASP A 135
ASP A 163
LYS A 181
 None
GOL  A 403 (-3.0A)
None
 1.11A 1lquB-5onuA:
undetectable		 1lquB-5onuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_A_REMA350_2
(RENIN)		 5onu OUTER MEMBRANE
PROTEIN OMPU
(Vibrio
cholerae) 		4 / 5 TYR A 320
ALA A 306
ALA A 286
TYR A 280
 None
None
C8E  A 401 ( 4.0A)
None
 1.22A 3d91A-5onuA:
undetectable		 3d91A-5onuA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 5onu OUTER MEMBRANE
PROTEIN OMPU
(Vibrio
cholerae) 		4 / 6 TYR A 119
GLY A  91
THR A 130
GLU A  84
 None
 0.96A 3fpjA-5onuA:
undetectable		 3fpjA-5onuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5onu OUTER MEMBRANE
PROTEIN OMPU
(Vibrio
cholerae) 		5 / 12 LEU A 138
ALA A 219
GLY A 231
GLY A 233
LEU A 217
 None
 1.15A 3ou6B-5onuA:
undetectable		 3ou6B-5onuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_A_SAMA300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5onu OUTER MEMBRANE
PROTEIN OMPU
(Vibrio
cholerae) 		5 / 12 LEU A 138
ALA A 219
GLY A 231
GLY A 233
LEU A 217
 None
 1.10A 3ou7A-5onuA:
undetectable		 3ou7A-5onuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5onu OUTER MEMBRANE
PROTEIN OMPU
(Vibrio
cholerae) 		5 / 12 LEU A 138
ALA A 219
GLY A 231
GLY A 233
LEU A 217
 None
 1.16A 3ou7B-5onuA:
undetectable		 3ou7B-5onuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5onu OUTER MEMBRANE
PROTEIN OMPU
(Vibrio
cholerae) 		5 / 12 LEU A 138
ALA A 219
GLY A 231
GLY A 233
LEU A 217
 None
 1.13A 3ou7D-5onuA:
undetectable		 3ou7D-5onuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_F_BEZF501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 5onu OUTER MEMBRANE
PROTEIN OMPU
(Vibrio
cholerae) 		4 / 8 SER A  73
ARG A 347
TYR A 320
ARG A  57
 None
None
None
GOL  A 402 ( 4.9A)
 1.13A 4ijiF-5onuA:
undetectable		 4ijiF-5onuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR4_C_AICC401_1
(OUTER MEMBRANE
PROTEIN F)		 5onu OUTER MEMBRANE
PROTEIN OMPU
(Vibrio
cholerae) 		4 / 8 ARG A  74
ARG A  76
ASP A 163
ARG A 116
 GOL  A 402 (-3.0A)
GOL  A 402 (-3.2A)
GOL  A 403 (-3.0A)
GOL  A 403 (-3.3A)
 1.23A 4kr4C-5onuA:
27.0		 4kr4C-5onuA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR4_C_AICC401_1
(OUTER MEMBRANE
PROTEIN F)		 5onu OUTER MEMBRANE
PROTEIN OMPU
(Vibrio
cholerae) 		4 / 8 ARG A 116
ARG A  74
ARG A  61
ASP A 146
 GOL  A 403 (-3.3A)
GOL  A 402 (-3.0A)
None
None
 1.41A 4kr4C-5onuA:
27.0		 4kr4C-5onuA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR4_C_AICC401_1
(OUTER MEMBRANE
PROTEIN F)		 5onu OUTER MEMBRANE
PROTEIN OMPU
(Vibrio
cholerae) 		4 / 8 TYR A 312
ARG A 318
ARG A 347
ASP A 146
 C8E  A 401 (-3.6A)
None
None
None
 1.21A 4kr4C-5onuA:
27.0		 4kr4C-5onuA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5I_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5onu OUTER MEMBRANE
PROTEIN OMPU
(Vibrio
cholerae) 		3 / 3 ASP A 143
ARG A  74
ARG A 116
 None
GOL  A 402 (-3.0A)
GOL  A 403 (-3.3A)
 0.94A 4x5iA-5onuA:
undetectable		 4x5iA-5onuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_H_TR6H101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 5onu OUTER MEMBRANE
PROTEIN OMPU
(Vibrio
cholerae) 		3 / 5 GLY A  93
GLY A 121
GLU A 128
 None
 0.41A 4z2eA-5onuA:
undetectable
4z2eD-5onuA:
undetectable		 4z2eA-5onuA:
11.98
4z2eD-5onuA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7B_A_PA1A206_1
(ACYLOXYACYL
HYDROLASE SMALL
SUBUNIT
ACYLOXYACYL
HYDROLASE LARGE
SUBUNIT)		 5onu OUTER MEMBRANE
PROTEIN OMPU
(Vibrio
cholerae) 		4 / 4 TYR A 184
GLY A 211
ASN A 210
ARG A 185
 None
 1.39A 5w7bA-5onuA:
undetectable
5w7bC-5onuA:
undetectable		 5w7bA-5onuA:
17.65
5w7bC-5onuA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_1
(MRNA CAPPING ENZYME
P5)		 5onu OUTER MEMBRANE
PROTEIN OMPU
(Vibrio
cholerae) 		3 / 3 TYR A 215
ASP A 213
ASP A 236
 None
 0.86A 5x6yA-5onuA:
undetectable		 5x6yA-5onuA:
undetectable