SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5oo7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_1
(HYPOTHETICAL PROTEIN
RV2118C)		 5oo7 SLA2
(Chaetomium
thermophilum) 		3 / 3 GLU A 135
HIS A 133
ASP A 153
 None
 0.82A 1i9gA-5oo7A:
undetectable		 1i9gA-5oo7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)		 5oo7 SLA2
(Chaetomium
thermophilum) 		4 / 8 ILE A 171
LEU A 167
PHE A 140
GLY A 138
 None
 0.87A 1os6A-5oo7A:
undetectable		 1os6A-5oo7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_2
(PROTEASE)		 5oo7 SLA2
(Chaetomium
thermophilum) 		3 / 3 ARG A  88
VAL A  78
THR A  43
 None
 0.81A 2nmzA-5oo7A:
undetectable		 2nmzA-5oo7A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_B_ADNB2_1
(YTAA PROTEIN)		 5oo7 SLA2
(Chaetomium
thermophilum) 		4 / 6 ILE A  75
TRP A  96
LEU A  62
ILE A  61
 None
 0.94A 2q83B-5oo7A:
2.0		 2q83B-5oo7A:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 5oo7 SLA2
(Chaetomium
thermophilum) 		4 / 8 ASN A 188
PHE A 182
TYR A 252
PHE A  69
 None
 1.27A 2wekA-5oo7A:
undetectable		 2wekA-5oo7A:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 5oo7 SLA2
(Chaetomium
thermophilum) 		4 / 8 ASN A 188
PHE A 182
TYR A 252
PHE A  69
 None
 1.25A 2wekB-5oo7A:
undetectable		 2wekB-5oo7A:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBZ_A_VDXA501_1
(CYTOCHROME P450-SU1)		 5oo7 SLA2
(Chaetomium
thermophilum) 		5 / 11 LEU A 164
SER A 211
MET A 212
ILE A 161
ALA A 235
 None
 1.17A 2zbzA-5oo7A:
undetectable		 2zbzA-5oo7A:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_B_D16B520_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5oo7 SLA2
(Chaetomium
thermophilum) 		5 / 12 ALA A 194
PHE A 243
ILE A 259
PRO A 260
LEU A 250
 None
 1.17A 3nrrB-5oo7A:
undetectable		 3nrrB-5oo7A:
8.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5P_A_TACA7101_1
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 5oo7 SLA2
(Chaetomium
thermophilum) 		5 / 12 PRO A 197
TYR A 244
ILE A  73
PHE A 174
ILE A 171
 None
 1.30A 3q5pA-5oo7A:
0.8		 3q5pA-5oo7A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5R_A_KANA2002_1
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 5oo7 SLA2
(Chaetomium
thermophilum) 		5 / 11 PRO A 197
TYR A 244
ILE A  73
PHE A 174
ILE A 171
 None
 1.25A 3q5rA-5oo7A:
undetectable		 3q5rA-5oo7A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SEL_X_DXCX75_0
(CYTOCHROME C7)		 5oo7 SLA2
(Chaetomium
thermophilum) 		4 / 8 ILE A 171
LEU A 167
PHE A 140
GLY A 138
 None
 0.91A 3selX-5oo7A:
undetectable		 3selX-5oo7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ1_X_DXCX75_0
(CYTOCHROME C7)		 5oo7 SLA2
(Chaetomium
thermophilum) 		4 / 6 ILE A 171
LEU A 167
PHE A 140
GLY A 138
 None
 1.03A 3sj1X-5oo7A:
undetectable		 3sj1X-5oo7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 5oo7 SLA2
(Chaetomium
thermophilum) 		4 / 5 TYR A 233
SER A 211
ASP A 172
ILE A 171
 None
 1.15A 3uj7B-5oo7A:
undetectable		 3uj7B-5oo7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AT0_A_ACTA1490_0
(3-KETOSTEROID-DELTA4
-5ALPHA-DEHYDROGENAS
E)		 5oo7 SLA2
(Chaetomium
thermophilum) 		3 / 3 GLU A 189
TYR A 252
SER A 193
 None
 1.00A 4at0A-5oo7A:
undetectable		 4at0A-5oo7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HC3_A_DXCA75_0
(PPCA)		 5oo7 SLA2
(Chaetomium
thermophilum) 		4 / 7 ILE A 171
LEU A 167
PHE A 140
GLY A 138
 None
 0.90A 4hc3A-5oo7A:
undetectable		 4hc3A-5oo7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_D_LOCD502_1
(TUBULIN BETA CHAIN)		 5oo7 SLA2
(Chaetomium
thermophilum) 		5 / 12 CYH A  39
LEU A  56
ALA A  71
ALA A  23
ILE A  75
 None
 1.16A 4x1iD-5oo7A:
undetectable		 4x1iD-5oo7A:
9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 5oo7 SLA2
(Chaetomium
thermophilum) 		3 / 3 GLU A 135
HIS A 133
ASP A 153
 None
 0.80A 5c0oG-5oo7A:
undetectable		 5c0oG-5oo7A:
undetectable