SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ooo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YA3_B_STRB2001_2 (MINERALOCORTICOID RECEPTOR)	5ooo	NON-STRUCTURAL PROTEIN NS-S (Rift Valley fever phlebovirus)	3 / 3	LEU A 197 LEU A 215 MET A 96	None	0.75A	1ya3B-5oooA: undetectable	1ya3B-5oooA: 20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2J2P_B_SC2B1290_1 (FICOLIN-2)	5ooo	NON-STRUCTURAL PROTEIN NS-S (Rift Valley fever phlebovirus)	4 / 8	SER A 119 LEU A 115 LEU A 144 ARG A 147	None	1.09A	2j2pA-5oooA: undetectable 2j2pB-5oooA: undetectable	2j2pA-5oooA: 19.53 2j2pB-5oooA: 19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VDY_A_HCYA1384_1 (CORTICOSTEROID-BINDI NG GLOBULIN)	5ooo	NON-STRUCTURAL PROTEIN NS-S (Rift Valley fever phlebovirus)	5 / 12	SER A 213 VAL A 217 GLN A 87 ILE A 93 SER A 127	None	1.48A	2vdyA-5oooA: undetectable	2vdyA-5oooA: 17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4BQF_A_QPSA951_1 (ALPHA-GLUCAN PHOSPHORYLASE 2, CYTOSOLIC)	5ooo	NON-STRUCTURAL PROTEIN NS-S (Rift Valley fever phlebovirus)	4 / 6	GLY A 116 TRP A 113 GLU A 169 ARG A 196	None	1.42A	4bqfA-5oooA: undetectable	4bqfA-5oooA: 13.07

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1YA3_B_STRB2001_2","MINERALOCORTICOID RECEPTOR","5ooo","NON-STRUCTURAL PROTEIN NS-S","Rift Valley fever phlebovirus",3,"LEU A 197;LEU A 215;MET A  96","None","0.75A","1ya3B-5oooA:undetectable","1ya3B-5oooA:20.33"],["2J2P_B_SC2B1290_1","FICOLIN-2;FICOLIN-2","5ooo","NON-STRUCTURAL PROTEIN NS-S","Rift Valley fever phlebovirus",4,"SER A 119;LEU A 115;LEU A 144;ARG A 147","None","1.09A","2j2pA-5oooA:undetectable;2j2pB-5oooA:undetectable","2j2pA-5oooA:19.53;2j2pB-5oooA:19.53"],["2VDY_A_HCYA1384_1","CORTICOSTEROID-BINDING GLOBULIN","5ooo","NON-STRUCTURAL PROTEIN NS-S","Rift Valley fever phlebovirus",5,"SER A 213;VAL A 217;GLN A  87;ILE A  93;SER A 127","None","1.48A","2vdyA-5oooA:undetectable","2vdyA-5oooA:17.55"],["4BQF_A_QPSA951_1","ALPHA-GLUCAN PHOSPHORYLASE 2, CYTOSOLIC","5ooo","NON-STRUCTURAL PROTEIN NS-S","Rift Valley fever phlebovirus",4,"GLY A 116;TRP A 113;GLU A 169;ARG A 196","None","1.42A","4bqfA-5oooA:undetectable","4bqfA-5oooA:13.07"]]