SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5oow'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1BRP_A_RTLA183_0 (RETINOL BINDING PROTEIN)	5oow	CHAPERONE PROTEIN DNAK (Escherichia coli)	5 / 12	LEU A 324 ALA A 191 PHE A 200 LEU A 219 PHE A 356	None	1.42A	1brpA-5oowA: undetectable	1brpA-5oowA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AQF_A_ADNA1382_1 (HEAT SHOCK COGNATE 71 KDA PROTEIN)	5oow	CHAPERONE PROTEIN DNAK (Escherichia coli)	6 / 10	GLY A 197 GLY A 229 GLU A 267 LYS A 270 SER A 274 GLY A 342	ACP A 401 (-3.0A) ACP A 401 ( 3.7A) ACP A 401 (-2.9A) ACP A 401 (-2.6A) ACP A 401 (-2.3A) ACP A 401 (-3.4A)	0.70A	5aqfA-5oowA: 4.8	5aqfA-5oowA: 14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AQF_C_ADNC1382_1 (HEAT SHOCK COGNATE 71 KDA PROTEIN)	5oow	CHAPERONE PROTEIN DNAK (Escherichia coli)	6 / 10	GLY A 197 GLY A 229 GLU A 267 LYS A 270 SER A 274 GLY A 342	ACP A 401 (-3.0A) ACP A 401 ( 3.7A) ACP A 401 (-2.9A) ACP A 401 (-2.6A) ACP A 401 (-2.3A) ACP A 401 (-3.4A)	0.69A	5aqfC-5oowA: 4.9	5aqfC-5oowA: 14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AQY_A_ADNA1389_1 (HEAT SHOCK 70 KDA PROTEIN 1A)	5oow	CHAPERONE PROTEIN DNAK (Escherichia coli)	6 / 10	GLY A 197 GLY A 229 GLU A 267 LYS A 270 SER A 274 GLY A 342	ACP A 401 (-3.0A) ACP A 401 ( 3.7A) ACP A 401 (-2.9A) ACP A 401 (-2.6A) ACP A 401 (-2.3A) ACP A 401 (-3.4A)	0.71A	5aqyA-5oowA: 4.6	5aqyA-5oowA: 15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TJY_A_BEZA304_0 (4-HYDROXY-TETRAHYDRO DIPICOLINATE REDUCTASE)	5oow	CHAPERONE PROTEIN DNAK (Escherichia coli)	3 / 3	MET A 259 GLU A 242 ARG A 253	None	1.13A	5tjyA-5oowA: undetectable	5tjyA-5oowA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TJZ_A_BEZA302_0 (4-HYDROXY-TETRAHYDRO DIPICOLINATE REDUCTASE)	5oow	CHAPERONE PROTEIN DNAK (Escherichia coli)	3 / 3	MET A 259 GLU A 242 ARG A 253	None	1.07A	5tjzA-5oowA: undetectable	5tjzA-5oowA: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1BRP_A_RTLA183_0","RETINOL BINDING PROTEIN","5oow","CHAPERONE PROTEIN DNAK","Escherichia coli",5,"LEU A 324;ALA A 191;PHE A 200;LEU A 219;PHE A 356","None","1.42A","1brpA-5oowA:undetectable","1brpA-5oowA:undetectable"],["5AQF_A_ADNA1382_1","HEAT SHOCK COGNATE 71 KDA PROTEIN","5oow","CHAPERONE PROTEIN DNAK","Escherichia coli",6,"GLY A 197;GLY A 229;GLU A 267;LYS A 270;SER A 274;GLY A 342","ACP A 401 (-3.0A);ACP A 401 ( 3.7A);ACP A 401 (-2.9A);ACP A 401 (-2.6A);ACP A 401 (-2.3A);ACP A 401 (-3.4A)","0.70A","5aqfA-5oowA:4.8","5aqfA-5oowA:14.93"],["5AQF_C_ADNC1382_1","HEAT SHOCK COGNATE 71 KDA PROTEIN","5oow","CHAPERONE PROTEIN DNAK","Escherichia coli",6,"GLY A 197;GLY A 229;GLU A 267;LYS A 270;SER A 274;GLY A 342","ACP A 401 (-3.0A);ACP A 401 ( 3.7A);ACP A 401 (-2.9A);ACP A 401 (-2.6A);ACP A 401 (-2.3A);ACP A 401 (-3.4A)","0.69A","5aqfC-5oowA:4.9","5aqfC-5oowA:14.93"],["5AQY_A_ADNA1389_1","HEAT SHOCK 70 KDA PROTEIN 1A","5oow","CHAPERONE PROTEIN DNAK","Escherichia coli",6,"GLY A 197;GLY A 229;GLU A 267;LYS A 270;SER A 274;GLY A 342","ACP A 401 (-3.0A);ACP A 401 ( 3.7A);ACP A 401 (-2.9A);ACP A 401 (-2.6A);ACP A 401 (-2.3A);ACP A 401 (-3.4A)","0.71A","5aqyA-5oowA:4.6","5aqyA-5oowA:15.27"],["5TJY_A_BEZA304_0","4-HYDROXY-TETRAHYDRODIPICOLINATE REDUCTASE","5oow","CHAPERONE PROTEIN DNAK","Escherichia coli",3,"MET A 259;GLU A 242;ARG A 253","None","1.13A","5tjyA-5oowA:undetectable","5tjyA-5oowA:undetectable"],["5TJZ_A_BEZA302_0","4-HYDROXY-TETRAHYDRODIPICOLINATE REDUCTASE","5oow","CHAPERONE PROTEIN DNAK","Escherichia coli",3,"MET A 259;GLU A 242;ARG A 253","None","1.07A","5tjzA-5oowA:undetectable","5tjzA-5oowA:undetectable"]]