SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5op0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMA_A_SAMA105_0
(PROTEIN (MET
REPRESSOR))		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		4 / 8 GLU B 206
ARG B 210
LEU B 163
GLU B 166
 None
 0.82A 1cmaA-5op0B:
undetectable
1cmaB-5op0B:
undetectable		 1cmaA-5op0B:
17.30
1cmaB-5op0B:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMA_B_SAMB105_0
(PROTEIN (MET
REPRESSOR))		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		5 / 11 GLU B 206
ARG B 210
LEU B 163
GLU B 166
GLY B 299
 None
 1.21A 1cmaA-5op0B:
undetectable
1cmaB-5op0B:
undetectable		 1cmaA-5op0B:
17.30
1cmaB-5op0B:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMC_B_SAMB105_0
(MET REPRESSOR)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		5 / 10 GLU B 206
ARG B 210
LEU B 163
GLU B 166
GLY B 299
 None
 1.18A 1cmcA-5op0B:
undetectable
1cmcB-5op0B:
undetectable		 1cmcA-5op0B:
17.30
1cmcB-5op0B:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_RALB600_1
(ESTROGEN RECEPTOR)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLU B 206
LEU B 203
LEU B 163
LEU B 185
LEU B 137
 None
 0.97A 1errB-5op0B:
undetectable		 1errB-5op0B:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCN_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
PEPTIDE
N-ACETYL-D-HIS-L-PRO
-NH2)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		3 / 3 PHE B 149
TYR B 272
PRO B 269
 None
 1.01A 1mcnA-5op0B:
undetectable
1mcnB-5op0B:
undetectable
1mcnP-5op0B:
undetectable		 1mcnA-5op0B:
21.73
1mcnB-5op0B:
21.73
1mcnP-5op0B:
2.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2200_0
(PROTEIN (METHIONINE
REPRESSOR))		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLY B 299
GLU B 206
ARG B 210
LEU B 163
GLU B 166
 None
 1.21A 1mj2A-5op0B:
undetectable
1mj2B-5op0B:
undetectable		 1mj2A-5op0B:
17.30
1mj2B-5op0B:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC2199_0
(PROTEIN (METHIONINE
REPRESSOR))		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLY B 299
GLU B 206
ARG B 210
LEU B 163
GLU B 166
 None
 1.21A 1mj2C-5op0B:
undetectable
1mj2D-5op0B:
undetectable		 1mj2C-5op0B:
17.30
1mj2D-5op0B:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJL_A_SAMA200_0
(METHIONINE REPRESSOR
PROTEIN METJ)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		5 / 11 ALA B 307
GLU B 206
ARG B 210
LEU B 163
GLU B 166
 None
 1.12A 1mjlA-5op0B:
undetectable
1mjlB-5op0B:
undetectable		 1mjlA-5op0B:
17.30
1mjlB-5op0B:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJL_B_SAMB400_0
(METHIONINE REPRESSOR
PROTEIN METJ)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		5 / 9 GLU B 206
ARG B 210
LEU B 163
GLU B 166
GLY B 299
 None
 1.14A 1mjlA-5op0B:
undetectable
1mjlB-5op0B:
undetectable		 1mjlA-5op0B:
17.30
1mjlB-5op0B:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_C_SAMC200_0
(METHIONINE REPRESSOR)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLY B 299
GLU B 206
ARG B 210
LEU B 163
GLU B 166
 None
 1.22A 1mjoC-5op0B:
undetectable
1mjoD-5op0B:
undetectable		 1mjoC-5op0B:
17.30
1mjoD-5op0B:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_A_SAMA200_0
(METHIONINE REPRESSOR)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		5 / 11 GLU B 206
ARG B 210
LEU B 163
GLU B 166
GLY B 299
 None
 1.13A 1mjqA-5op0B:
undetectable
1mjqB-5op0B:
undetectable		 1mjqA-5op0B:
17.30
1mjqB-5op0B:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_B_SAMB200_0
(METHIONINE REPRESSOR)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		5 / 11 GLY B 299
GLU B 206
ARG B 210
LEU B 163
GLU B 166
 None
 1.15A 1mjqA-5op0B:
undetectable
1mjqB-5op0B:
undetectable		 1mjqA-5op0B:
17.30
1mjqB-5op0B:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_C_SAMC199_0
(METHIONINE REPRESSOR)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		5 / 10 GLU B 206
ARG B 210
LEU B 163
GLU B 166
GLY B 299
 None
 1.20A 1mjqC-5op0B:
undetectable
1mjqD-5op0B:
undetectable		 1mjqC-5op0B:
17.30
1mjqD-5op0B:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_D_SAMD200_0
(METHIONINE REPRESSOR)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLY B 299
GLU B 206
ARG B 210
LEU B 163
GLU B 166
 None
 1.11A 1mjqC-5op0B:
undetectable
1mjqD-5op0B:
undetectable		 1mjqC-5op0B:
17.30
1mjqD-5op0B:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_H_SAMH200_0
(METHIONINE REPRESSOR)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		5 / 10 GLY B 299
GLU B 206
ARG B 210
LEU B 163
GLU B 166
 None
 1.15A 1mjqG-5op0B:
undetectable
1mjqH-5op0B:
undetectable		 1mjqG-5op0B:
17.30
1mjqH-5op0B:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_I_SAMI199_0
(METHIONINE REPRESSOR)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		5 / 11 GLU B 206
ARG B 210
LEU B 163
GLU B 166
GLY B 299
 None
 1.21A 1mjqI-5op0B:
undetectable
1mjqJ-5op0B:
undetectable		 1mjqI-5op0B:
17.30
1mjqJ-5op0B:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_J_SAMJ200_0
(METHIONINE REPRESSOR)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLY B 299
GLU B 206
ARG B 210
LEU B 163
GLU B 166
 None
 1.10A 1mjqI-5op0B:
undetectable
1mjqJ-5op0B:
undetectable		 1mjqI-5op0B:
17.30
1mjqJ-5op0B:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S8F_B_BEZB1503_0
(RAS-RELATED PROTEIN
RAB-9A)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		4 / 6 GLU B 208
LEU B 228
ARG B 227
PHE B 229
 None
 1.10A 1s8fB-5op0B:
undetectable		 1s8fB-5op0B:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		5 / 12 TYR B  74
ASP B 238
PRO B 123
THR B 120
SER B 176
 None
 1.21A 1xoqA-5op0B:
undetectable		 1xoqA-5op0B:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		5 / 12 TYR B  74
ASP B 238
PRO B 123
THR B 120
SER B 176
 None
 1.22A 1xoqB-5op0B:
undetectable		 1xoqB-5op0B:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZUC_B_T98B202_1
(PROGESTERONE
RECEPTOR)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU B 304
LEU B 301
LEU B 298
LEU B 185
LEU B 163
 None
 1.04A 1zucB-5op0B:
undetectable		 1zucB-5op0B:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COJ_A_GBNA420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		5 / 11 PHE B  26
TYR B  42
THR B 120
GLY B 117
ALA B 114
 None
 1.41A 2cojA-5op0B:
undetectable
2cojB-5op0B:
undetectable		 2cojA-5op0B:
20.10
2cojB-5op0B:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA2_0
(FERROCHELATASE)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		4 / 8 MET B  50
LEU B  54
PRO B 258
VAL B 255
 None
 1.01A 2qd2A-5op0B:
undetectable		 2qd2A-5op0B:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_A_ASDA1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		4 / 7 PRO B 173
LEU B 264
ALA B 267
PHE B 149
 None
 0.98A 2vcvA-5op0B:
undetectable		 2vcvA-5op0B:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_G_ASDG1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		4 / 7 PRO B 173
LEU B 264
ALA B 267
PHE B 149
 None
 0.97A 2vcvG-5op0B:
undetectable		 2vcvG-5op0B:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_D_ROFD904_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		5 / 12 TYR B  74
ASP B 238
PRO B 123
THR B 120
SER B 176
 None
 1.23A 3g4lD-5op0B:
undetectable		 3g4lD-5op0B:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		4 / 4 LEU B 301
PRO B 300
LEU B 304
ARG B 210
 None
 1.37A 3hcoA-5op0B:
undetectable		 3hcoA-5op0B:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_E_NIOE5660_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		3 / 3 GLU B 223
GLU B 222
TRP B 219
 None
 1.26A 3hrdA-5op0B:
undetectable
3hrdE-5op0B:
undetectable
3hrdF-5op0B:
undetectable		 3hrdA-5op0B:
22.99
3hrdE-5op0B:
22.99
3hrdF-5op0B:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		3 / 3 ARG B  55
ASP B 135
ASP B  56
 None
 0.90A 3jayA-5op0B:
undetectable		 3jayA-5op0B:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		3 / 3 ARG B  55
ASP B 135
ASP B  56
 None
 0.92A 3jb3A-5op0B:
undetectable		 3jb3A-5op0B:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_B_VIBB223_1
(THIAMINE
PYROPHOSPHOKINASE)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		4 / 7 LEU B 185
LEU B 203
ASN B 235
THR B 217
 None
 1.06A 3lm8B-5op0B:
undetectable
3lm8D-5op0B:
undetectable		 3lm8B-5op0B:
21.41
3lm8D-5op0B:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_C_LYAC304_2
(FOLATE RECEPTOR BETA)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		3 / 3 TYR B 322
GLN B 234
TRP B 219
 None
 1.17A 4kn2C-5op0B:
undetectable		 4kn2C-5op0B:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		4 / 7 VAL B  45
ILE B 110
ILE B 111
ALA B 114
 None
 0.93A 4lv9B-5op0B:
undetectable		 4lv9B-5op0B:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_B_CHDB102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		5 / 11 LEU B 169
LEU B 164
LEU B 185
ALA B 202
LEU B 203
 None
 0.98A 4wg0B-5op0B:
undetectable
4wg0C-5op0B:
undetectable
4wg0D-5op0B:
undetectable		 4wg0B-5op0B:
6.91
4wg0C-5op0B:
6.91
4wg0D-5op0B:
6.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_D_CHDD102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		5 / 11 LEU B 169
LEU B 164
LEU B 185
ALA B 202
LEU B 203
 None
 0.97A 4wg0D-5op0B:
undetectable
4wg0E-5op0B:
undetectable
4wg0F-5op0B:
undetectable		 4wg0D-5op0B:
6.91
4wg0E-5op0B:
6.91
4wg0F-5op0B:
6.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_E_CHDE104_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		5 / 11 ALA B 202
LEU B 203
LEU B 185
LEU B 169
LEU B 164
 None
 1.00A 4wg0C-5op0B:
undetectable
4wg0D-5op0B:
undetectable
4wg0E-5op0B:
undetectable		 4wg0C-5op0B:
6.91
4wg0D-5op0B:
6.91
4wg0E-5op0B:
6.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_F_CHDF103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		5 / 11 LEU B 169
LEU B 164
LEU B 185
ALA B 202
LEU B 203
 None
 1.00A 4wg0F-5op0B:
undetectable
4wg0G-5op0B:
undetectable
4wg0H-5op0B:
undetectable		 4wg0F-5op0B:
6.91
4wg0G-5op0B:
6.91
4wg0H-5op0B:
6.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_G_CHDG103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		5 / 11 ALA B 202
LEU B 203
LEU B 185
LEU B 169
LEU B 164
 None
 0.99A 4wg0E-5op0B:
undetectable
4wg0F-5op0B:
undetectable
4wg0G-5op0B:
undetectable		 4wg0E-5op0B:
6.91
4wg0F-5op0B:
6.91
4wg0G-5op0B:
6.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_H_CHDH103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		5 / 11 LEU B 169
LEU B 164
LEU B 185
ALA B 202
LEU B 203
 None
 1.00A 4wg0H-5op0B:
undetectable
4wg0I-5op0B:
undetectable
4wg0J-5op0B:
undetectable		 4wg0H-5op0B:
6.91
4wg0I-5op0B:
6.91
4wg0J-5op0B:
6.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_I_CHDI103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		5 / 11 ALA B 202
LEU B 203
LEU B 185
LEU B 169
LEU B 164
 None
 0.96A 4wg0G-5op0B:
undetectable
4wg0H-5op0B:
undetectable
4wg0I-5op0B:
undetectable		 4wg0G-5op0B:
6.91
4wg0H-5op0B:
6.91
4wg0I-5op0B:
6.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_J_CHDJ103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		5 / 11 LEU B 169
LEU B 164
LEU B 185
ALA B 202
LEU B 203
 None
 0.97A 4wg0J-5op0B:
undetectable
4wg0K-5op0B:
undetectable
4wg0L-5op0B:
undetectable		 4wg0J-5op0B:
6.91
4wg0K-5op0B:
6.91
4wg0L-5op0B:
6.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_K_CHDK103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		5 / 11 ALA B 202
LEU B 203
LEU B 185
LEU B 169
LEU B 164
 None
 0.96A 4wg0I-5op0B:
undetectable
4wg0J-5op0B:
undetectable
4wg0K-5op0B:
undetectable		 4wg0I-5op0B:
6.91
4wg0J-5op0B:
6.91
4wg0K-5op0B:
6.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_M_CHDM103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		5 / 11 ALA B 202
LEU B 203
LEU B 185
LEU B 169
LEU B 164
 None
 1.00A 4wg0K-5op0B:
undetectable
4wg0L-5op0B:
undetectable
4wg0M-5op0B:
undetectable		 4wg0K-5op0B:
6.91
4wg0L-5op0B:
6.91
4wg0M-5op0B:
6.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_C_ACTC1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		3 / 3 TYR B 272
THR B 254
THR B 276
 None
 0.82A 5aoxB-5op0B:
undetectable		 5aoxB-5op0B:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_F_ACTF1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		3 / 3 TYR B 272
THR B 254
THR B 276
 None
 0.82A 5aoxE-5op0B:
undetectable		 5aoxE-5op0B:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA816_0
(UNCHARACTERIZED
PROTEIN)		 5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN
(Mycolicibacteriu
m
smegmatis) 		3 / 3 ARG B 205
ARG B 311
ASP B 308
 None
 0.83A 6d8pA-5op0B:
undetectable		 6d8pA-5op0B:
17.57