SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5opg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2503_0
(FERROCHELATASE)		 5opg ENVELOPE
GLYCOPROTEIN GN
(Hantaan
orthohantavirus) 		4 / 4 LEU A  46
PRO A 140
LEU A 161
ARG A 165
 None
 1.26A 1hrkB-5opgA:
undetectable		 1hrkB-5opgA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1604_0
(FERROCHELATASE)		 5opg ENVELOPE
GLYCOPROTEIN GN
(Hantaan
orthohantavirus) 		4 / 4 LEU A  46
PRO A 140
LEU A 161
ARG A 165
 None
 1.27A 2hrcB-5opgA:
undetectable		 2hrcB-5opgA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1121_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5opg ENVELOPE
GLYCOPROTEIN GN
(Hantaan
orthohantavirus) 		4 / 5 SER A 339
VAL A 337
SER A 323
SER A 326
 None
 1.15A 2j9cA-5opgA:
undetectable
2j9cB-5opgA:
undetectable
2j9cC-5opgA:
undetectable		 2j9cA-5opgA:
16.09
2j9cB-5opgA:
16.09
2j9cC-5opgA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5opg ENVELOPE
GLYCOPROTEIN GN
(Hantaan
orthohantavirus) 		4 / 4 LEU A  46
PRO A 140
LEU A 161
ARG A 165
 None
 1.26A 2pnjB-5opgA:
undetectable		 2pnjB-5opgA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA426_0
(FERROCHELATASE)		 5opg ENVELOPE
GLYCOPROTEIN GN
(Hantaan
orthohantavirus) 		4 / 4 LEU A  46
PRO A 140
LEU A 161
ARG A 165
 None
 1.24A 2qd2A-5opgA:
undetectable		 2qd2A-5opgA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1499_1
(CYTOCHROME P450 3A4)		 5opg ENVELOPE
GLYCOPROTEIN GN
(Hantaan
orthohantavirus) 		4 / 5 PHE A  96
PHE A 343
SER A 291
ILE A 319
 None
None
None
NAG  A 407 (-3.7A)
 1.36A 2v0mD-5opgA:
undetectable		 2v0mD-5opgA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_1
(PCZA361.24)		 5opg ENVELOPE
GLYCOPROTEIN GN
(Hantaan
orthohantavirus) 		3 / 3 ARG A 172
GLU A 371
ASP A 189
 None
 0.85A 3g2oA-5opgA:
undetectable		 3g2oA-5opgA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 5opg ENVELOPE
GLYCOPROTEIN GN
(Hantaan
orthohantavirus) 		4 / 6 PHE A 223
PHE A 274
THR A 329
VAL A 241
 None
 1.32A 3lb3B-5opgA:
undetectable		 3lb3B-5opgA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_G_FK5G201_1
(FK506-BINDING
PROTEIN 1)		 5opg ENVELOPE
GLYCOPROTEIN GN
(Hantaan
orthohantavirus) 		3 / 3 ILE A 356
PRO A 357
ILE A 327
 None
 0.45A 5hw8F-5opgA:
undetectable		 5hw8F-5opgA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_B_PFLB407_1
(PROTON-GATED ION
CHANNEL)		 5opg ENVELOPE
GLYCOPROTEIN GN
(Hantaan
orthohantavirus) 		4 / 7 TYR A 143
ILE A  41
ILE A 145
ILE A 246
 None
 0.91A 5murB-5opgA:
undetectable		 5murB-5opgA:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UBB_A_SAMA301_0
(ALPHA N-TERMINAL
PROTEIN
METHYLTRANSFERASE 1B)		 5opg ENVELOPE
GLYCOPROTEIN GN
(Hantaan
orthohantavirus) 		5 / 12 SER A 354
LEU A 311
GLN A  79
VAL A 337
LEU A 328
 None
 1.24A 5ubbA-5opgA:
undetectable		 5ubbA-5opgA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5opg ENVELOPE
GLYCOPROTEIN GN
(Hantaan
orthohantavirus) 		4 / 6 MET A  25
ARG A 165
ALA A 160
LEU A 161
 None
 1.09A 6fosB-5opgA:
undetectable		 6fosB-5opgA:
13.13