SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5opi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_C_9CRC502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5opi TAP BINDING
PROTEIN-LIKE VARIANT
(Homo
sapiens) 		5 / 10 ALA C  79
SER C 197
PHE C 173
ALA C 199
PHE C 124
 None
 1.15A 1g5yC-5opiC:
undetectable		 1g5yC-5opiC:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 5opi TAP BINDING
PROTEIN-LIKE VARIANT
(Homo
sapiens) 		4 / 8 THR C 256
GLN C 218
ARG C 216
ILE C 257
 None
 0.90A 1rxcB-5opiC:
undetectable		 1rxcB-5opiC:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_2
(PROTEIN S100-A4)		 5opi TAP BINDING
PROTEIN-LIKE VARIANT
(Homo
sapiens) 		4 / 6 LEU C  44
SER C  43
PHE C  77
ILE C 106
 None
 0.99A 3ko0B-5opiC:
undetectable		 3ko0B-5opiC:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_D_NCTD501_1
(CYTOCHROME P450 2A6)		 5opi TAP BINDING
PROTEIN-LIKE VARIANT
(Homo
sapiens) 		4 / 7 PHE C 124
ILE C  75
LEU C  23
PHE C  77
 None
 0.88A 4ejjD-5opiC:
undetectable		 4ejjD-5opiC:
22.16