SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5opj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_B_RBFB302_1
(PROTEIN (FLAVODOXIN))		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ASP A 193
GLY A 233
ASP A 234
TYR A 237
 None
 1.03A 1bu5B-5opjA:
undetectable		 1bu5B-5opjA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTB_A_PZQA901_0
(GLUTATHIONE
S-TRANSFERASE)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		3 / 3 GLN A 461
TYR A 379
ARG A 376
 None
 0.78A 1gtbA-5opjA:
1.8		 1gtbA-5opjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_A_BEZA1162_0
(PEROXIREDOXIN 5)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		5 / 10 THR A 136
PRO A 137
GLY A 138
LEU A 158
GLY A 160
 None
 1.33A 1h4oA-5opjA:
undetectable
1h4oB-5opjA:
undetectable		 1h4oA-5opjA:
undetectable
1h4oB-5opjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IVV_A_DAHA382_1
(AMINE OXIDASE)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		5 / 10 THR A 343
ASN A 266
TYR A 344
HIS A  93
HIS A  89
 None
AHR  A 901 (-3.7A)
None
None
None
 1.35A 1ivvA-5opjA:
undetectable		 1ivvA-5opjA:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4H_A_REAA500_1
(NUCLEAR RECEPTOR
ROR-BETA)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		5 / 11 CYH A 782
ILE A 724
VAL A 680
VAL A 800
LEU A 773
 None
 1.26A 1n4hA-5opjA:
undetectable		 1n4hA-5opjA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		5 / 11 THR A 136
GLY A 134
GLU A  82
SER A 139
ILE A 133
 None
 1.47A 1odiA-5opjA:
undetectable		 1odiA-5opjA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		5 / 11 THR A 136
GLY A 134
GLU A  82
SER A 139
ILE A 133
 None
 1.45A 1odiC-5opjA:
undetectable		 1odiC-5opjA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_C_DEXC3999_1
(GLUCOCORTICOID
RECEPTOR)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		5 / 12 GLY A 219
LEU A 214
MET A 213
LEU A 158
THR A 136
 None
 1.25A 1p93C-5opjA:
undetectable		 1p93C-5opjA:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q13_A_TESA501_1
(PROSTAGLANDIN-E2
9-REDUCTASE)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		4 / 6 TYR A 646
HIS A 642
PRO A 338
VAL A 394
 None
 1.31A 1q13A-5opjA:
undetectable		 1q13A-5opjA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1300_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		5 / 11 GLY A 135
PHE A  65
ALA A 124
LEU A 121
VAL A 128
 None
 1.13A 1ukbA-5opjA:
undetectable		 1ukbA-5opjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA801_1
(TRANSPORTER)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		5 / 11 LEU A 205
GLN A 211
ILE A 146
PHE A 244
LEU A 158
 None
 0.94A 2q6hA-5opjA:
undetectable		 2q6hA-5opjA:
8.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA801_1
(TRANSPORTER)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		5 / 11 LEU A 205
GLN A 211
ILE A 146
PHE A 244
LEU A 158
 None
 0.95A 2q72A-5opjA:
0.3		 2q72A-5opjA:
8.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA801_1
(TRANSPORTER)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 205
GLN A 211
ILE A 146
PHE A 244
LEU A 158
 None
 0.93A 2qb4A-5opjA:
undetectable		 2qb4A-5opjA:
8.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_B_CHDB504_0
(FERROCHELATASE)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ILE A 110
ARG A 113
PRO A 410
SER A 408
 None
 1.42A 2qd3B-5opjA:
undetectable		 2qd3B-5opjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA801_1
(TRANSPORTER)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		5 / 11 LEU A 205
GLN A 211
ILE A 146
PHE A 244
LEU A 158
 None
 0.93A 2qeiA-5opjA:
0.5		 2qeiA-5opjA:
8.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QJU_A_DSMA801_1
(TRANSPORTER)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		5 / 11 LEU A 205
GLN A 211
ILE A 146
PHE A 244
LEU A 158
 None
 0.93A 2qjuA-5opjA:
undetectable		 2qjuA-5opjA:
8.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_GLYA502_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		4 / 7 SER A 420
HIS A 169
HIS A  93
TYR A 344
 ZN  A 902 ( 4.8A)
None
None
None
 0.92A 2vmyA-5opjA:
undetectable
2vmyB-5opjA:
undetectable		 2vmyA-5opjA:
undetectable
2vmyB-5opjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_B_GLYB502_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		4 / 8 TYR A 344
SER A 420
HIS A 169
HIS A  93
 None
ZN  A 902 ( 4.8A)
None
None
 0.97A 2vmyA-5opjA:
undetectable
2vmyB-5opjA:
undetectable		 2vmyA-5opjA:
undetectable
2vmyB-5opjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_A_ACHA1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		4 / 7 SER A 781
CYH A 782
GLN A 697
ILE A 784
 None
 1.30A 2xz5A-5opjA:
undetectable
2xz5B-5opjA:
undetectable		 2xz5A-5opjA:
undetectable
2xz5B-5opjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_A_SAMA300_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		5 / 9 ALA A  69
GLY A 134
GLY A 135
LEU A  71
ALA A 124
 None
 0.91A 2z0yA-5opjA:
undetectable		 2z0yA-5opjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_B_SAMB400_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		5 / 9 ALA A  69
GLY A 134
GLY A 135
LEU A  71
ALA A 124
 None
 0.88A 2z0yB-5opjA:
undetectable		 2z0yB-5opjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		4 / 4 ARG A 123
GLN A 125
PHE A 132
LEU A  66
 None
 1.46A 3abkC-5opjA:
1.7		 3abkC-5opjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ARG A 123
GLN A 125
PHE A 132
LEU A  66
 None
 1.38A 3ablC-5opjA:
undetectable
3ablJ-5opjA:
undetectable		 3ablC-5opjA:
undetectable
3ablJ-5opjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_B_DP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 432
PHE A 465
LEU A 536
GLN A 461
TYR A 379
 None
 1.32A 3apwB-5opjA:
undetectable		 3apwB-5opjA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_B_LOCB700_2
(TUBULIN BETA-2B
CHAIN)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		5 / 11 LEU A 731
LEU A 769
ALA A 743
VAL A 797
LYS A 742
 None
 1.31A 3e22B-5opjA:
undetectable		 3e22B-5opjA:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FGR_B_ACTB21_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		4 / 4 ARG A 369
ASP A 361
ASP A 367
PRO A 368
 None
 1.09A 3fgrB-5opjA:
undetectable		 3fgrB-5opjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWV_A_RFXA801_1
(TRANSPORTER)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 205
GLN A 211
ILE A 146
PHE A 244
LEU A 158
 None
 0.92A 3gwvA-5opjA:
undetectable		 3gwvA-5opjA:
8.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_E_NIOE5660_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		3 / 3 GLU A 320
GLU A 339
TRP A  81
 AHR  A 901 (-2.7A)
AHR  A 901 ( 2.7A)
None
 1.11A 3hrdA-5opjA:
undetectable
3hrdE-5opjA:
undetectable
3hrdF-5opjA:
undetectable		 3hrdA-5opjA:
12.40
3hrdE-5opjA:
12.40
3hrdF-5opjA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U6T_A_KANA4699_1
(RIBOSOME
INACTIVATING PROTEIN)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		5 / 10 SER A 781
ASN A 721
TYR A 720
ILE A 683
GLU A 691
 None
 1.35A 3u6tA-5opjA:
undetectable		 3u6tA-5opjA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A  60
GLU A  82
THR A  79
 None
 0.88A 3v4tA-5opjA:
undetectable		 3v4tA-5opjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB504_1
(HEMOLYTIC LECTIN
CEL-III)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ASP A  49
GLU A 423
GLY A 421
GLN A 386
 None
 1.25A 3w9tB-5opjA:
undetectable		 3w9tB-5opjA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE505_1
(HEMOLYTIC LECTIN
CEL-III)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ASP A  49
GLU A 423
GLY A 421
GLN A 386
 None
 1.25A 3w9tE-5opjA:
undetectable		 3w9tE-5opjA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1476_0
(MJ0495-LIKE PROTEIN)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ILE A 133
ALA A  69
HIS A 122
ARG A 123
 None
 1.05A 4ac9B-5opjA:
undetectable
4ac9C-5opjA:
2.3		 4ac9B-5opjA:
undetectable
4ac9C-5opjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1478_0
(MJ0495-LIKE PROTEIN)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ASP A 227
GLY A 174
THR A 171
PHE A 225
 None
 0.77A 4ac9C-5opjA:
2.3		 4ac9C-5opjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1476_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ILE A 133
ALA A  69
HIS A 122
ARG A 123
 None
 1.07A 4acaB-5opjA:
undetectable
4acaC-5opjA:
undetectable		 4acaB-5opjA:
undetectable
4acaC-5opjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ASP A 227
GLY A 174
THR A 171
PHE A 225
 None
 0.76A 4acaC-5opjA:
undetectable		 4acaC-5opjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM0_B_KANB302_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		5 / 11 LEU A 347
THR A 350
TYR A 374
LEU A 444
ARG A 488
 None
 1.45A 4em0B-5opjA:
undetectable		 4em0B-5opjA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HC3_A_DXCA75_0
(PPCA)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ILE A  90
LEU A 422
PHE A 393
LYS A 390
 None
 0.93A 4hc3A-5opjA:
undetectable		 4hc3A-5opjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_A_SAMA1546_0
(CYSTATHIONINE
BETA-SYNTHASE)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		5 / 11 LEU A 238
ALA A 241
HIS A 246
ASP A 207
ASP A 251
 None
 1.37A 4uuuA-5opjA:
undetectable
4uuuB-5opjA:
undetectable		 4uuuA-5opjA:
undetectable
4uuuB-5opjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJ8_A_SUVA2001_1
(HUMAN OX1R FUSION
PROTEIN TO P.ABYSII
GLYCOGEN SYNTHASE)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ALA A 575
VAL A 406
GLN A 689
GLU A 320
HIS A 585
 None
None
AHR  A 901 (-3.6A)
AHR  A 901 (-2.7A)
None
 1.42A 4zj8A-5opjA:
undetectable		 4zj8A-5opjA:
8.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJL_A_ERYA1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ASN A 345
SER A  96
ASP A 227
GLU A 223
 None
 1.10A 4zjlA-5opjA:
0.0		 4zjlA-5opjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_A_FOLA201_0
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 258
THR A 304
ASN A 316
VAL A 311
HIS A 264
 None
None
None
None
AHR  A 901 (-3.9A)
 1.45A 5d0yA-5opjA:
undetectable		 5d0yA-5opjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_B_FOLB201_0
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 258
THR A 304
ASN A 316
VAL A 311
HIS A 264
 None
None
None
None
AHR  A 901 (-3.9A)
 1.46A 5d0yB-5opjA:
undetectable		 5d0yB-5opjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_B_QELB503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		5 / 11 THR A 463
PRO A 447
ILE A 446
PHE A 445
PRO A 637
 None
 1.41A 5ewjA-5opjA:
undetectable
5ewjB-5opjA:
undetectable		 5ewjA-5opjA:
12.50
5ewjB-5opjA:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		5 / 12 THR A 463
PRO A 447
ILE A 446
PHE A 445
PRO A 637
 None
 1.41A 5ewjC-5opjA:
undetectable
5ewjD-5opjA:
undetectable		 5ewjC-5opjA:
12.50
5ewjD-5opjA:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC0_A_RBFA303_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 361
GLY A 358
ALA A 434
ASN A 443
PHE A 431
 None
 0.97A 5kc0A-5opjA:
undetectable		 5kc0A-5opjA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 361
GLY A 358
ALA A 434
ASN A 443
PHE A 431
 None
 0.93A 5kc4A-5opjA:
undetectable		 5kc4A-5opjA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWY_A_YNUA1101_0
(MINERALOCORTICOID
RECEPTOR)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 186
LEU A 118
ASN A 119
SER A  62
MET A 190
 None
 1.19A 5mwyA-5opjA:
undetectable		 5mwyA-5opjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA602_0
(THIOCYANATE
DEHYDROGENASE)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		3 / 3 LYS A 271
HIS A 246
HIS A 218
 None
 1.34A 5oexA-5opjA:
undetectable		 5oexA-5opjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB602_0
(THIOCYANATE
DEHYDROGENASE)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		3 / 3 LYS A 271
HIS A 246
HIS A 218
 None
 1.36A 5oexB-5opjA:
undetectable		 5oexB-5opjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC603_0
(THIOCYANATE
DEHYDROGENASE)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		3 / 3 LYS A 271
HIS A 246
HIS A 218
 None
 1.34A 5oexC-5opjA:
undetectable		 5oexC-5opjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD603_0
(THIOCYANATE
DEHYDROGENASE)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		3 / 3 LYS A 271
HIS A 246
HIS A 218
 None
 1.30A 5oexD-5opjA:
undetectable		 5oexD-5opjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGQ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		5 / 9 ALA A 178
LEU A 118
MET A 117
GLY A  91
HIS A  93
 None
 1.36A 5wgqA-5opjA:
undetectable		 5wgqA-5opjA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGQ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		5 / 9 ALA A 178
LEU A 118
MET A 117
GLY A  92
HIS A  93
 None
 1.40A 5wgqA-5opjA:
undetectable		 5wgqA-5opjA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		3 / 3 TYR A 798
ARG A 709
THR A 705
 None
 0.92A 5z84J-5opjA:
undetectable		 5z84J-5opjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 313
HIS A 381
THR A 340
VAL A 394
LEU A 332
 None
 1.14A 6djzA-5opjA:
undetectable		 6djzA-5opjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA826_0
(GEPHYRIN)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		3 / 3 HIS A 508
ARG A 524
ILE A 503
 None
 0.72A 6fgdA-5opjA:
undetectable		 6fgdA-5opjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNA_A_ACTA307_0
(THIOREDOXIN
REDUCTASE)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A 348
LYS A 351
TYR A 374
 None
 1.26A 6gnaA-5opjA:
undetectable		 6gnaA-5opjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNB_A_ACTA307_0
(THIOREDOXIN
REDUCTASE)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A 348
LYS A 351
TYR A 374
 None
 1.26A 6gnbA-5opjA:
undetectable		 6gnbA-5opjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		4 / 4 ARG A 123
GLN A 125
PHE A 132
LEU A  66
 None
 1.39A 6nmfC-5opjA:
1.8		 6nmfC-5opjA:
undetectable