SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5opq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		5 / 10 ALA A 163
PHE A 164
ALA A  74
LEU A 109
VAL A 107
 None
 1.08A 1claA-5opqA:
undetectable		 1claA-5opqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4002_1
(SERUM ALBUMIN)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		3 / 3 PHE A 588
LEU A 553
SER A 642
 CL  A 704 ( 4.8A)
None
None
 0.83A 1e7aA-5opqA:
undetectable		 1e7aA-5opqA:
10.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		5 / 11 GLN A 566
GLY A 532
GLU A 531
GLY A 519
THR A 534
 TRS  A 703 ( 3.0A)
None
TRS  A 703 ( 4.6A)
None
CL  A 704 ( 4.4A)
 0.98A 1jg3A-5opqA:
undetectable		 1jg3A-5opqA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_B_ADNB550_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		5 / 11 GLN A 566
GLY A 532
GLU A 531
GLY A 519
THR A 534
 TRS  A 703 ( 3.0A)
None
TRS  A 703 ( 4.6A)
None
CL  A 704 ( 4.4A)
 0.99A 1jg3B-5opqA:
undetectable		 1jg3B-5opqA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHU_A_ESTA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		5 / 12 GLY A 401
ASP A 359
LYS A 362
ILE A 395
LEU A 478
 None
 1.01A 1lhuA-5opqA:
undetectable		 1lhuA-5opqA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2201_1
(PROTEIN (METHIONINE
REPRESSOR))		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		4 / 4 HIS A 518
ALA A 490
PHE A 489
GLY A 519
 None
 0.87A 1mj2B-5opqA:
undetectable		 1mj2B-5opqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC1200_1
(PROTEIN (METHIONINE
REPRESSOR))		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		4 / 4 HIS A 518
ALA A 490
PHE A 489
GLY A 519
 None
 0.87A 1mj2D-5opqA:
undetectable		 1mj2D-5opqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_A_SAMA199_1
(METHIONINE REPRESSOR)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		4 / 4 HIS A 518
ALA A 490
PHE A 489
GLY A 519
 None
 0.90A 1mjoB-5opqA:
undetectable		 1mjoB-5opqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_B_SAMB200_0
(METHIONINE REPRESSOR)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		4 / 4 HIS A 518
ALA A 490
PHE A 489
GLY A 519
 None
 0.93A 1mjoA-5opqA:
undetectable		 1mjoA-5opqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_D_SAMD200_1
(METHIONINE REPRESSOR)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		4 / 4 HIS A 518
ALA A 490
PHE A 489
GLY A 519
 None
 0.86A 1mjoD-5opqA:
undetectable		 1mjoD-5opqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NHZ_A_486A800_1
(GLUCOCORTICOID
RECEPTOR)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		5 / 12 GLY A 221
GLN A 179
LEU A 541
GLN A 249
LEU A 275
 None
 1.25A 1nhzA-5opqA:
undetectable		 1nhzA-5opqA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OSV_A_CHCA202_1
(BILE ACID RECEPTOR)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		5 / 12 ALA A 244
ILE A 239
TYR A 292
TRP A 227
TRP A 279
 None
 1.40A 1osvA-5opqA:
0.1		 1osvA-5opqA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q13_A_TESA501_1
(PROSTAGLANDIN-E2
9-REDUCTASE)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		4 / 6 TYR A 492
HIS A 316
GLU A 494
VAL A 242
 None
 1.36A 1q13A-5opqA:
7.5		 1q13A-5opqA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_B_C2FB802_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		5 / 12 GLU A 472
GLY A 465
ASP A 483
SER A 420
ILE A 475
 None
 1.14A 1q8jB-5opqA:
7.4		 1q8jB-5opqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		4 / 8 THR A 592
GLY A 335
MET A 586
ILE A 337
 None
 0.81A 1rxcB-5opqA:
undetectable		 1rxcB-5opqA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		4 / 8 THR A 592
GLY A 335
MET A 586
ILE A 337
 None
 0.82A 1rxcE-5opqA:
undetectable		 1rxcE-5opqA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_I_URFI2041_1
(URIDINE
PHOSPHORYLASE)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		4 / 8 THR A 592
GLY A 335
MET A 586
ILE A 337
 None
 0.80A 1rxcI-5opqA:
undetectable		 1rxcI-5opqA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		4 / 8 THR A 592
GLY A 335
MET A 586
ILE A 337
 None
 0.84A 1rxcK-5opqA:
undetectable		 1rxcK-5opqA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB503_1
(YKOF)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		4 / 7 PHE A 578
ILE A 368
ILE A 608
THR A 592
 None
 0.76A 1sbrB-5opqA:
undetectable		 1sbrB-5opqA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_A_LEUA1894_0
(AMINOACYL-TRNA
SYNTHETASE)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		4 / 8 ASP A 636
SER A 634
TYR A 188
HIS A 546
 None
 1.19A 2bteA-5opqA:
undetectable		 2bteA-5opqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_D_LEUD1893_0
(AMINOACYL-TRNA
SYNTHETASE)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		4 / 8 ASP A 636
SER A 634
TYR A 188
HIS A 546
 None
 1.26A 2bteD-5opqA:
undetectable		 2bteD-5opqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_B_ADNB902_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		5 / 11 PHE A  54
ALA A  73
ASN A  72
VAL A 142
TYR A 292
 None
 1.42A 2gl0B-5opqA:
undetectable
2gl0C-5opqA:
undetectable		 2gl0B-5opqA:
17.79
2gl0C-5opqA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_D_ADND904_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		5 / 12 PHE A  54
ALA A  73
ASN A  72
VAL A 142
TYR A 292
 None
 1.45A 2gl0D-5opqA:
undetectable
2gl0E-5opqA:
undetectable		 2gl0D-5opqA:
17.79
2gl0E-5opqA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA703_0
(FERROCHELATASE)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		4 / 4 LEU A 553
PRO A 549
LEU A 627
ARG A 643
 None
 1.30A 2hrcA-5opqA:
undetectable		 2hrcA-5opqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1290_1
(FICOLIN-2)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		4 / 8 SER A 421
SER A 420
LEU A 480
ASP A 483
 None
 0.57A 2j2pA-5opqA:
undetectable
2j2pB-5opqA:
undetectable		 2j2pA-5opqA:
14.49
2j2pB-5opqA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		5 / 9 GLU A 631
GLU A 649
ILE A 651
GLU A 662
ILE A 661
 None
 1.24A 2j9dA-5opqA:
0.0
2j9dB-5opqA:
undetectable
2j9dC-5opqA:
undetectable		 2j9dA-5opqA:
undetectable
2j9dB-5opqA:
undetectable
2j9dC-5opqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		5 / 9 GLU A 649
ILE A 651
GLU A 662
ILE A 661
GLU A 631
 None
 1.25A 2j9dA-5opqA:
0.0
2j9dB-5opqA:
undetectable
2j9dC-5opqA:
undetectable		 2j9dA-5opqA:
undetectable
2j9dB-5opqA:
undetectable
2j9dC-5opqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		5 / 9 GLU A 662
ILE A 661
GLU A 631
GLU A 649
ILE A 651
 None
 1.26A 2j9dA-5opqA:
0.0
2j9dB-5opqA:
undetectable
2j9dC-5opqA:
undetectable		 2j9dA-5opqA:
undetectable
2j9dB-5opqA:
undetectable
2j9dC-5opqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_E_ACTE1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		5 / 10 GLU A 631
GLU A 649
ILE A 651
GLU A 662
ILE A 661
 None
 1.22A 2j9dD-5opqA:
undetectable
2j9dE-5opqA:
undetectable
2j9dF-5opqA:
0.0		 2j9dD-5opqA:
undetectable
2j9dE-5opqA:
undetectable
2j9dF-5opqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_E_ACTE1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		5 / 10 GLU A 649
ILE A 651
GLU A 662
ILE A 661
GLU A 631
 None
 1.25A 2j9dD-5opqA:
undetectable
2j9dE-5opqA:
undetectable
2j9dF-5opqA:
0.0		 2j9dD-5opqA:
undetectable
2j9dE-5opqA:
undetectable
2j9dF-5opqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_E_ACTE1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		5 / 10 GLU A 662
ILE A 661
GLU A 631
GLU A 649
ILE A 651
 None
 1.23A 2j9dD-5opqA:
undetectable
2j9dE-5opqA:
undetectable
2j9dF-5opqA:
0.0		 2j9dD-5opqA:
undetectable
2j9dE-5opqA:
undetectable
2j9dF-5opqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_H_ACTH1113_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		5 / 9 GLU A 631
GLU A 649
ILE A 651
GLU A 662
ILE A 661
 None
 1.23A 2j9dG-5opqA:
0.0
2j9dH-5opqA:
undetectable
2j9dI-5opqA:
undetectable		 2j9dG-5opqA:
undetectable
2j9dH-5opqA:
undetectable
2j9dI-5opqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_H_ACTH1113_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		5 / 9 GLU A 649
ILE A 651
GLU A 662
ILE A 661
GLU A 631
 None
 1.20A 2j9dG-5opqA:
0.0
2j9dH-5opqA:
undetectable
2j9dI-5opqA:
undetectable		 2j9dG-5opqA:
undetectable
2j9dH-5opqA:
undetectable
2j9dI-5opqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_H_ACTH1113_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		5 / 9 GLU A 662
ILE A 661
GLU A 631
GLU A 649
ILE A 651
 None
 1.22A 2j9dG-5opqA:
0.0
2j9dH-5opqA:
undetectable
2j9dI-5opqA:
undetectable		 2j9dG-5opqA:
undetectable
2j9dH-5opqA:
undetectable
2j9dI-5opqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_J_ACTJ1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		5 / 8 GLU A 649
ILE A 651
GLU A 662
ILE A 661
GLU A 631
 None
 1.24A 2j9dJ-5opqA:
undetectable
2j9dK-5opqA:
undetectable
2j9dL-5opqA:
undetectable		 2j9dJ-5opqA:
undetectable
2j9dK-5opqA:
undetectable
2j9dL-5opqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_D_SNLD4001_1
(MINERALOCORTICOID
RECEPTOR)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		5 / 12 LEU A 166
ALA A 174
LEU A 275
LEU A 541
PHE A 190
 None
 1.40A 2oaxD-5opqA:
undetectable		 2oaxD-5opqA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_1
(MINERALOCORTICOID
RECEPTOR)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		5 / 12 LEU A 166
ALA A 174
LEU A 275
LEU A 541
PHE A 190
 None
 1.42A 2oaxF-5opqA:
undetectable		 2oaxF-5opqA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		3 / 3 ASN A 193
ARG A 196
ASP A 577
 None
 0.63A 2qe6A-5opqA:
undetectable		 2qe6A-5opqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		3 / 3 ASN A 193
ARG A 196
ASP A 577
 None
 0.64A 2qe6B-5opqA:
undetectable		 2qe6B-5opqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X08_A_ASCA1253_0
(CYTOCHROME C
PEROXIDASE,
MITOCHONDRIAL)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		5 / 9 ASP A 486
ILE A 487
TYR A 425
PRO A 427
VAL A 389
 TRS  A 703 (-3.1A)
TRS  A 703 (-4.7A)
None
None
None
 1.21A 2x08A-5opqA:
undetectable		 2x08A-5opqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_C_H4BC2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		4 / 7 MET A 224
ILE A 239
TRP A 226
GLU A 521
 None
 1.43A 3e7gC-5opqA:
undetectable
3e7gD-5opqA:
undetectable		 3e7gC-5opqA:
11.03
3e7gD-5opqA:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_D_H4BD3902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		4 / 8 GLU A 521
MET A 224
ILE A 239
TRP A 226
 None
 1.43A 3e7gC-5opqA:
undetectable
3e7gD-5opqA:
undetectable		 3e7gC-5opqA:
11.03
3e7gD-5opqA:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		6 / 11 GLY A 591
GLY A 589
PHE A 588
THR A 622
ALA A 336
ALA A 582
 None
None
CL  A 704 ( 4.8A)
None
None
None
 1.38A 3g88A-5opqA:
undetectable		 3g88A-5opqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		6 / 11 GLY A 591
GLY A 589
PHE A 588
THR A 622
ALA A 336
ALA A 582
 None
None
CL  A 704 ( 4.8A)
None
None
None
 1.37A 3g88B-5opqA:
undetectable		 3g88B-5opqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		6 / 11 GLY A 591
GLY A 589
PHE A 588
THR A 622
ALA A 336
ALA A 582
 None
None
CL  A 704 ( 4.8A)
None
None
None
 1.43A 3g89B-5opqA:
undetectable		 3g89B-5opqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAN_A_SVRA158_1
(UNCHARACTERIZED
PROTEIN AT3G22680)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		5 / 11 TYR A 422
VAL A 389
PRO A 390
ILE A 565
ILE A 484
 None
None
None
TRS  A 703 (-4.9A)
None
 1.50A 3ganA-5opqA:
undetectable		 3ganA-5opqA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_B_CHDB1_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		4 / 4 LEU A 553
PRO A 549
LEU A 627
ARG A 643
 None
 1.19A 3hcoB-5opqA:
undetectable		 3hcoB-5opqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_A_ADNA300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		5 / 11 VAL A 301
ILE A 184
ASP A 299
LEU A 550
ALA A 548
 None
 1.24A 3kw2A-5opqA:
2.9		 3kw2A-5opqA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_B_ADNB300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		5 / 11 VAL A 301
ILE A 184
ASP A 299
LEU A 550
ALA A 548
 None
 1.17A 3kw2B-5opqA:
undetectable		 3kw2B-5opqA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_A_4CHA191_0
(DEHALOPEROXIDASE A)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		4 / 6 PHE A 644
HIS A 619
THR A 622
VAL A 618
 None
 1.25A 3lb3A-5opqA:
undetectable		 3lb3A-5opqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		4 / 6 PHE A 644
HIS A 619
THR A 622
VAL A 618
 None
 1.15A 3lb3B-5opqA:
undetectable		 3lb3B-5opqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OCT_A_1N1A663_2
(TYROSINE-PROTEIN
KINASE BTK)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		4 / 5 PHE A 164
ILE A 272
ASN A  44
PHE A 274
 None
 1.41A 3octA-5opqA:
undetectable		 3octA-5opqA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_1
(N-METHYLTRANSFERASE)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		3 / 3 TYR A 188
TYR A 637
GLU A 232
 None
 0.96A 3pfgA-5opqA:
2.3		 3pfgA-5opqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SU9_A_ACTA426_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		3 / 3 GLN A 468
GLU A 502
LYS A 464
 None
 0.99A 3su9A-5opqA:
undetectable		 3su9A-5opqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_J_ZPCJ1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		4 / 5 GLU A 521
PHE A 317
TYR A 307
HIS A 293
 None
 1.32A 4a97J-5opqA:
undetectable		 4a97J-5opqA:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD392_1
(TETX2 PROTEIN)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		4 / 5 HIS A 630
SER A 642
GLN A 640
VAL A 650
 None
 1.34A 4a99D-5opqA:
undetectable		 4a99D-5opqA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_D_H4BD600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		4 / 7 GLU A 521
MET A 224
ILE A 239
TRP A 226
 None
 1.42A 4cx7C-5opqA:
undetectable
4cx7D-5opqA:
undetectable		 4cx7C-5opqA:
10.82
4cx7D-5opqA:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR5_A_SRYA1860_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S12)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		3 / 3 LYS A  66
PRO A  69
LYS A 167
 None
 1.36A 4dr5L-5opqA:
undetectable		 4dr5L-5opqA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUZ_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		3 / 3 LYS A  66
PRO A  69
LYS A 167
 None
 1.36A 4duzL-5opqA:
undetectable		 4duzL-5opqA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV7_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		3 / 3 LYS A  66
PRO A  69
LYS A 167
 None
 1.19A 4dv7L-5opqA:
undetectable		 4dv7L-5opqA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_2
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		3 / 3 LYS A  86
THR A  78
ILE A 278
 None
 0.77A 4e0fB-5opqA:
undetectable		 4e0fB-5opqA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		4 / 8 THR A 592
GLY A 335
MET A 586
ILE A 337
 None
 0.85A 4e1vA-5opqA:
undetectable		 4e1vA-5opqA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_C_URFC1301_1
(URIDINE
PHOSPHORYLASE)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		4 / 8 THR A 592
GLY A 335
MET A 586
ILE A 337
 None
 0.85A 4e1vC-5opqA:
undetectable		 4e1vC-5opqA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		4 / 8 THR A 592
GLY A 335
MET A 586
ILE A 337
 None
 0.84A 4e1vD-5opqA:
undetectable		 4e1vD-5opqA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		4 / 8 THR A 592
GLY A 335
MET A 586
ILE A 337
 None
 0.84A 4e1vE-5opqA:
undetectable		 4e1vE-5opqA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_G_URFG1301_1
(URIDINE
PHOSPHORYLASE)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		4 / 8 THR A 592
GLY A 335
MET A 586
ILE A 337
 None
 0.86A 4e1vG-5opqA:
undetectable		 4e1vG-5opqA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		4 / 8 THR A 592
GLY A 335
MET A 586
ILE A 337
 None
 0.84A 4e1vH-5opqA:
undetectable		 4e1vH-5opqA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_B_715B801_1
(DIPEPTIDYL PEPTIDASE
4)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		5 / 12 GLU A 517
GLY A 532
SER A 426
VAL A 389
TYR A 422
 TRS  A 703 (-2.9A)
None
None
None
None
 1.43A 4ffwB-5opqA:
undetectable		 4ffwB-5opqA:
7.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_2
(ADENOSINE KINASE)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		4 / 4 LEU A 418
SER A 420
LEU A 512
LEU A 333
 None
 0.81A 4n09A-5opqA:
undetectable		 4n09A-5opqA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_2
(ADENOSINE KINASE)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		4 / 5 LEU A 418
SER A 420
LEU A 512
LEU A 333
 None
 0.80A 4n09B-5opqA:
undetectable		 4n09B-5opqA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_2
(ADENOSINE KINASE)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		4 / 5 LEU A 418
SER A 420
LEU A 512
LEU A 333
 None
 0.79A 4n09D-5opqA:
undetectable		 4n09D-5opqA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_2
(ANDROGEN RECEPTOR)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		4 / 6 MET A 529
ILE A 608
ILE A 368
VAL A 374
 None
 0.95A 4olmA-5opqA:
undetectable		 4olmA-5opqA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1007_1
(SERUM ALBUMIN)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		5 / 9 TRP A 226
LEU A 275
LEU A 541
ILE A 252
ALA A 174
 None
 1.16A 4z69A-5opqA:
undetectable		 4z69A-5opqA:
10.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ACTA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		4 / 6 PRO A 568
ARG A 590
THR A 592
ILE A 594
 None
CL  A 704 (-4.9A)
None
None
 1.45A 5ih0A-5opqA:
1.1		 5ih0A-5opqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA612_1
(SERUM ALBUMIN)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		5 / 12 LEU A 654
LEU A 587
HIS A 630
ARG A 641
ILE A 667
 None
 1.10A 5v0vA-5opqA:
undetectable		 5v0vA-5opqA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_1
(REGULATORY PROTEIN
TETR)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		4 / 7 GLY A 228
GLN A 181
TYR A 535
TYR A 307
 None
 1.11A 5vlmG-5opqA:
undetectable		 5vlmG-5opqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_B_STRB502_1
(CYTOCHROME P450
CYP260A1)		 5opq 3,6-ANHYDRO-D-GALACT
OSIDASE
(Zobellia
galactanivorans) 		4 / 6 LEU A 480
LEU A 405
SER A 420
THR A 384
 None
 0.97A 6f88B-5opqA:
undetectable		 6f88B-5opqA:
22.09