SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5oq3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 5oq3 CWP19
(Clostridioides
difficile) 		3 / 3 ASN A 355
ARG A 356
ASP A 381
 None
 0.97A 2qe6A-5oq3A:
undetectable		 2qe6A-5oq3A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 5oq3 CWP19
(Clostridioides
difficile) 		3 / 3 ASN A 355
ARG A 356
ASP A 381
 None
 0.94A 2qe6B-5oq3A:
undetectable		 2qe6B-5oq3A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMQ_A_BEZA3_0
(PROTEIN NDRG2)		 5oq3 CWP19
(Clostridioides
difficile) 		4 / 7 TYR A 386
TYR A 366
ARG A 356
ARG A  33
 None
 1.31A 2qmqA-5oq3A:
undetectable		 2qmqA-5oq3A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLJ_A_SPMA1303_1
(POTASSIUM CHANNEL)		 5oq3 CWP19
(Clostridioides
difficile) 		3 / 3 ARG A 132
ARG A  79
PRO A  80
 None
 0.99A 2wljA-5oq3A:
undetectable		 2wljA-5oq3A:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_D_DVAD8_0
(GRAMICIDIN A)		 5oq3 CWP19
(Clostridioides
difficile) 		3 / 3 TRP A 127
VAL A 192
TRP A  36
 None
 1.28A 2xdcC-5oq3A:
undetectable
2xdcD-5oq3A:
undetectable		 2xdcC-5oq3A:
4.88
2xdcD-5oq3A:
4.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_F_DVAF8_0
(GRAMICIDIN A)		 5oq3 CWP19
(Clostridioides
difficile) 		3 / 3 TRP A 127
VAL A 192
TRP A  36
 None
 1.26A 2xdcE-5oq3A:
undetectable
2xdcF-5oq3A:
undetectable		 2xdcE-5oq3A:
4.88
2xdcF-5oq3A:
4.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_F_DVAF8_0
(VAL-GRAMICIDIN A)		 5oq3 CWP19
(Clostridioides
difficile) 		3 / 3 TRP A 127
VAL A 192
TRP A  36
 None
 1.25A 2y5mE-5oq3A:
undetectable
2y5mF-5oq3A:
undetectable		 2y5mE-5oq3A:
4.88
2y5mF-5oq3A:
4.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_D_DVAD8_0
(VAL-GRAMICIDIN A)		 5oq3 CWP19
(Clostridioides
difficile) 		3 / 3 TRP A 127
VAL A 192
TRP A  36
 None
 1.23A 2y6nC-5oq3A:
undetectable
2y6nD-5oq3A:
undetectable		 2y6nC-5oq3A:
4.88
2y6nD-5oq3A:
4.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_F_DVAF8_0
(VAL-GRAMICIDIN A)		 5oq3 CWP19
(Clostridioides
difficile) 		3 / 3 TRP A 127
VAL A 192
TRP A  36
 None
 1.25A 2y6nE-5oq3A:
undetectable
2y6nF-5oq3A:
undetectable		 2y6nE-5oq3A:
4.88
2y6nF-5oq3A:
4.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 5oq3 CWP19
(Clostridioides
difficile) 		3 / 3 LEU A 310
TRP A 313
GLY A 264
 None
 0.79A 3l35A-5oq3A:
undetectable
3l35H-5oq3A:
undetectable		 3l35A-5oq3A:
7.94
3l35H-5oq3A:
3.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 5oq3 CWP19
(Clostridioides
difficile) 		3 / 3 LEU A 310
TRP A 313
GLY A 264
 None
 0.75A 3l35B-5oq3A:
undetectable
3l35K-5oq3A:
undetectable		 3l35B-5oq3A:
7.94
3l35K-5oq3A:
3.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_A_9PLA501_1
(CYTOCHROME P450 2A6)		 5oq3 CWP19
(Clostridioides
difficile) 		6 / 11 PHE A 194
VAL A 227
PHE A 198
ILE A 176
LEU A 231
PHE A 247
 None
 1.49A 3t3rA-5oq3A:
undetectable		 3t3rA-5oq3A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 5oq3 CWP19
(Clostridioides
difficile) 		5 / 10 PHE A 194
VAL A 227
PHE A 198
ILE A 176
PHE A 247
 None
 1.34A 3t3rD-5oq3A:
undetectable		 3t3rD-5oq3A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4N_C_ACTC201_0
(NITROGEN REGULATORY
PROTEIN P-II)		 5oq3 CWP19
(Clostridioides
difficile) 		4 / 5 VAL A 183
VAL A 192
GLY A 191
PHE A 128
 None
 1.09A 5d4nA-5oq3A:
undetectable
5d4nC-5oq3A:
undetectable		 5d4nA-5oq3A:
12.81
5d4nC-5oq3A:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_2
(PROTEIN CYP51)		 5oq3 CWP19
(Clostridioides
difficile) 		4 / 6 PRO A  46
PRO A 109
LEU A 110
PHE A 112
 None
 0.75A 5tl8A-5oq3A:
undetectable		 5tl8A-5oq3A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_0
(REGULATORY PROTEIN
TETR)		 5oq3 CWP19
(Clostridioides
difficile) 		5 / 12 ALA A 282
VAL A 227
ASP A 196
PHE A 198
THR A 276
 None
 1.45A 5vlmD-5oq3A:
undetectable		 5vlmD-5oq3A:
15.42