SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5oqd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_1
(RETINOIC ACID
RECEPTOR, BETA)		 5oqd POLYCOMB PROTEIN PCL
(Drosophila
melanogaster) 		5 / 12 LEU B 585
ILE B 603
ILE B 607
LEU B 636
LEU B 658
 None
 1.15A 1xdkB-5oqdB:
undetectable		 1xdkB-5oqdB:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5oqd POLYCOMB PROTEIN PCL
(Drosophila
melanogaster) 		4 / 5 ARG B 611
VAL B 580
LEU B 581
MET B 629
 None
 1.32A 4e1gA-5oqdB:
undetectable		 4e1gA-5oqdB:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_E_IPHE101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 5oqd POLYCOMB PROTEIN PCL
(Drosophila
melanogaster) 		4 / 7 ILE B 575
HIS B 582
LEU B 581
ALA B 584
 None
 0.97A 5hrqE-5oqdB:
undetectable
5hrqF-5oqdB:
undetectable
5hrqJ-5oqdB:
undetectable		 5hrqE-5oqdB:
8.70
5hrqF-5oqdB:
18.26
5hrqJ-5oqdB:
18.26