SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5oqj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 5oqj RNA POLYMERASE II
TRANSCRIPTION FACTOR
B SUBUNIT 1
(Saccharomyces
cerevisiae) 		3 / 3 ARG 1  30
ILE 1  16
TRP 1  29
 None
 0.90A 1nodB-5oqj1:
undetectable		 1nodB-5oqj1:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QOM_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 5oqj RNA POLYMERASE II
TRANSCRIPTION FACTOR
B SUBUNIT 1
(Saccharomyces
cerevisiae) 		3 / 3 ARG 1  30
ILE 1  16
TRP 1  29
 None
 0.91A 1qomA-5oqj1:
undetectable		 1qomA-5oqj1:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5oqj RNA POLYMERASE II
TRANSCRIPTION FACTOR
B SUBUNIT 1
(Saccharomyces
cerevisiae) 		4 / 8 LEU 1  60
PHE 1  91
THR 1  28
LEU 1  27
 None
 0.68A 2eijN-5oqj1:
undetectable
2eijW-5oqj1:
undetectable		 2eijN-5oqj1:
undetectable
2eijW-5oqj1:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5oqj RNA POLYMERASE II
TRANSCRIPTION FACTOR
B SUBUNIT 1
(Saccharomyces
cerevisiae) 		4 / 7 LEU 1  60
PHE 1  91
THR 1  28
LEU 1  27
 None
 0.64A 2eikA-5oqj1:
undetectable
2eikJ-5oqj1:
undetectable		 2eikA-5oqj1:
undetectable
2eikJ-5oqj1:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5oqj RNA POLYMERASE II
TRANSCRIPTION FACTOR
B SUBUNIT 1
(Saccharomyces
cerevisiae) 		4 / 8 LEU 1  60
PHE 1  91
THR 1  28
LEU 1  27
 None
 0.63A 2eikN-5oqj1:
undetectable
2eikW-5oqj1:
undetectable		 2eikN-5oqj1:
undetectable
2eikW-5oqj1:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5oqj RNA POLYMERASE II
TRANSCRIPTION FACTOR
B SUBUNIT 1
(Saccharomyces
cerevisiae) 		4 / 8 LEU 1  60
PHE 1  91
THR 1  28
LEU 1  27
 None
 0.65A 2eilN-5oqj1:
undetectable
2eilW-5oqj1:
undetectable		 2eilN-5oqj1:
undetectable
2eilW-5oqj1:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_A_ANWA99_0
(PROTEIN S100-A13)		 5oqj RNA POLYMERASE II
TRANSCRIPTION FACTOR
B SUBUNIT 1
(Saccharomyces
cerevisiae) 		4 / 7 VAL 1 199
THR 1 198
PHE 1 195
ARG 1 213
 None
 1.27A 2kotA-5oqj1:
undetectable		 2kotA-5oqj1:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 5oqj RNA POLYMERASE II
TRANSCRIPTION FACTOR
B SUBUNIT 1
(Saccharomyces
cerevisiae) 		3 / 3 ARG 1  30
ILE 1  16
TRP 1  29
 None
 0.88A 2nodB-5oqj1:
undetectable		 2nodB-5oqj1:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN0_A_TDZA501_1
(CYTOCHROME P450 2C8)		 5oqj TRANSCRIPTION
INITIATION FACTOR
IIE SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		5 / 12 PHE W  15
LEU W  12
ASN W  11
VAL W 102
ILE W   8
 None
 1.17A 2vn0A-5oqjW:
undetectable		 2vn0A-5oqjW:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5oqj RNA POLYMERASE II
TRANSCRIPTION FACTOR
B SUBUNIT 1
(Saccharomyces
cerevisiae) 		4 / 8 LEU 1  60
PHE 1  91
THR 1  28
LEU 1  27
 None
 0.62A 3ag3N-5oqj1:
3.5
3ag3W-5oqj1:
undetectable		 3ag3N-5oqj1:
undetectable
3ag3W-5oqj1:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E68_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5oqj RNA POLYMERASE II
TRANSCRIPTION FACTOR
B SUBUNIT 1
(Saccharomyces
cerevisiae) 		3 / 3 ARG 1  30
ILE 1  16
TRP 1  29
 None
 1.10A 3e68A-5oqj1:
undetectable		 3e68A-5oqj1:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E6T_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5oqj RNA POLYMERASE II
TRANSCRIPTION FACTOR
B SUBUNIT 1
(Saccharomyces
cerevisiae) 		3 / 3 ARG 1  30
ILE 1  16
TRP 1  29
 None
 1.05A 3e6tB-5oqj1:
undetectable		 3e6tB-5oqj1:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7I_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5oqj RNA POLYMERASE II
TRANSCRIPTION FACTOR
B SUBUNIT 1
(Saccharomyces
cerevisiae) 		3 / 3 ARG 1  30
ILE 1  16
TRP 1  29
 None
 0.96A 3e7iB-5oqj1:
undetectable		 3e7iB-5oqj1:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 5oqj SUPPRESSOR OF
STEM-LOOP PROTEIN 1
(Saccharomyces
cerevisiae) 		5 / 10 LEU 6 221
ILE 6 127
SER 6 183
SER 6 186
GLY 6 170
 None
 1.36A 3ik6B-5oqj6:
undetectable
3ik6E-5oqj6:
undetectable		 3ik6B-5oqj6:
13.90
3ik6E-5oqj6:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_B_HFZB800_1
(GLUTAMATE RECEPTOR 2)		 5oqj SUPPRESSOR OF
STEM-LOOP PROTEIN 1
(Saccharomyces
cerevisiae) 		5 / 10 LEU 6 221
ILE 6 127
SER 6 183
SER 6 186
GLY 6 170
 None
 1.38A 3iluB-5oqj6:
undetectable
3iluE-5oqj6:
undetectable		 3iluB-5oqj6:
13.90
3iluE-5oqj6:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_A_LYAA514_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 5oqj RNA POLYMERASE II
TRANSCRIPTION FACTOR
B SUBUNIT 1
(Saccharomyces
cerevisiae) 		5 / 12 ALA 1  50
LEU 1  62
ILE 1  16
LEU 1  27
LEU 1 104
 None
 1.12A 3k2hA-5oqj1:
undetectable		 3k2hA-5oqj1:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5oqj RNA POLYMERASE II
TRANSCRIPTION FACTOR
B SUBUNIT 1
(Saccharomyces
cerevisiae) 		3 / 3 ARG 1  30
ILE 1  16
TRP 1  29
 None
 1.01A 3nw2A-5oqj1:
undetectable		 3nw2A-5oqj1:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5oqj RNA POLYMERASE II
TRANSCRIPTION FACTOR
B SUBUNIT 1
(Saccharomyces
cerevisiae) 		3 / 3 ARG 1  30
ILE 1  16
TRP 1  29
 None
 0.89A 3nw2B-5oqj1:
undetectable		 3nw2B-5oqj1:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P6G_A_IZPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5oqj SUPPRESSOR OF
STEM-LOOP PROTEIN 1
(Saccharomyces
cerevisiae) 		5 / 12 VAL 6 232
PRO 6 208
ILE 6 272
VAL 6 270
CYH 6 273
 None
 1.26A 3p6gA-5oqj6:
undetectable		 3p6gA-5oqj6:
25.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB323_0
(INVASIN IPAD)		 5oqj TRANSCRIPTION
INITIATION FACTOR
IIE SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		4 / 7 ILE W  98
ILE W  95
VAL W   9
LEU W  12
 None
 0.66A 3r9vA-5oqjW:
undetectable
3r9vB-5oqjW:
3.0		 3r9vA-5oqjW:
undetectable
3r9vB-5oqjW:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_0
(HYDG PROTEIN)		 5oqj SUPPRESSOR OF
STEM-LOOP PROTEIN 1
(Saccharomyces
cerevisiae) 		5 / 12 LEU 6 276
LEU 6 264
LEU 6 297
ALA 6 153
PHE 6 156
 None
 1.38A 4rtbA-5oqj6:
undetectable		 4rtbA-5oqj6:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5oqj RNA POLYMERASE II
TRANSCRIPTION FACTOR
B SUBUNIT 1
(Saccharomyces
cerevisiae) 		4 / 8 LEU 1  60
PHE 1  91
THR 1  28
LEU 1  27
 None
 0.66A 5zcoA-5oqj1:
undetectable
5zcoJ-5oqj1:
undetectable		 5zcoA-5oqj1:
undetectable
5zcoJ-5oqj1:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_A_6T0A910_0
(TOLL-LIKE RECEPTOR 7)		 5oqj SUPPRESSOR OF
STEM-LOOP PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 7 THR 6 280
LEU 6 254
ILE 6 247
THR 6 250
 None
 0.97A 5zsfA-5oqj6:
undetectable
5zsfB-5oqj6:
undetectable		 5zsfA-5oqj6:
16.30
5zsfB-5oqj6:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5oqj RNA POLYMERASE II
TRANSCRIPTION FACTOR
B SUBUNIT 1
(Saccharomyces
cerevisiae) 		4 / 8 ASN 1  92
PHE 1  91
ASN 1  99
ASP 1  98
 None
 1.19A 6auuB-5oqj1:
undetectable		 6auuB-5oqj1:
undetectable