SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5oqm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 5oqm GENERAL
TRANSCRIPTION AND
DNA REPAIR FACTOR
IIH SUBUNIT TFB1
(Saccharomyces
cerevisiae) 		3 / 3 ARG 1  30
ILE 1  16
TRP 1  29
 None
 0.87A 1nodB-5oqm1:
undetectable		 1nodB-5oqm1:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QOM_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 5oqm GENERAL
TRANSCRIPTION AND
DNA REPAIR FACTOR
IIH SUBUNIT TFB1
(Saccharomyces
cerevisiae) 		3 / 3 ARG 1  30
ILE 1  16
TRP 1  29
 None
 0.90A 1qomA-5oqm1:
undetectable		 1qomA-5oqm1:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN0_B_T44B602_1
(TRANSTHYRETIN)		 5oqm GENERAL
TRANSCRIPTION AND
DNA REPAIR FACTOR
IIH HELICASE SUBUNIT
XPB
(Saccharomyces
cerevisiae) 		4 / 7 LYS 7 766
LEU 7 579
GLU 7 769
ALA 7 614
 None
 1.01A 1sn0B-5oqm7:
undetectable
1sn0D-5oqm7:
undetectable		 1sn0B-5oqm7:
24.41
1sn0D-5oqm7:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5oqm GENERAL
TRANSCRIPTION AND
DNA REPAIR FACTOR
IIH SUBUNIT TFB1
(Saccharomyces
cerevisiae) 		4 / 8 LEU 1  60
PHE 1  91
THR 1  28
LEU 1  27
 None
 0.69A 2eijN-5oqm1:
undetectable
2eijW-5oqm1:
undetectable		 2eijN-5oqm1:
undetectable
2eijW-5oqm1:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5oqm GENERAL
TRANSCRIPTION AND
DNA REPAIR FACTOR
IIH SUBUNIT TFB1
(Saccharomyces
cerevisiae) 		4 / 7 LEU 1  60
PHE 1  91
THR 1  28
LEU 1  27
 None
 0.67A 2eikA-5oqm1:
undetectable
2eikJ-5oqm1:
undetectable		 2eikA-5oqm1:
undetectable
2eikJ-5oqm1:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5oqm GENERAL
TRANSCRIPTION AND
DNA REPAIR FACTOR
IIH SUBUNIT TFB1
(Saccharomyces
cerevisiae) 		4 / 8 LEU 1  60
PHE 1  91
THR 1  28
LEU 1  27
 None
 0.67A 2eikN-5oqm1:
undetectable
2eikW-5oqm1:
undetectable		 2eikN-5oqm1:
undetectable
2eikW-5oqm1:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5oqm GENERAL
TRANSCRIPTION AND
DNA REPAIR FACTOR
IIH SUBUNIT TFB1
(Saccharomyces
cerevisiae) 		4 / 8 LEU 1  60
PHE 1  91
THR 1  28
LEU 1  27
 None
 0.67A 2eilN-5oqm1:
undetectable
2eilW-5oqm1:
undetectable		 2eilN-5oqm1:
undetectable
2eilW-5oqm1:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_A_ANWA99_0
(PROTEIN S100-A13)		 5oqm GENERAL
TRANSCRIPTION AND
DNA REPAIR FACTOR
IIH SUBUNIT TFB1
(Saccharomyces
cerevisiae) 		4 / 7 VAL 1 199
THR 1 198
PHE 1 195
ARG 1 213
 None
 1.27A 2kotA-5oqm1:
undetectable		 2kotA-5oqm1:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 5oqm GENERAL
TRANSCRIPTION AND
DNA REPAIR FACTOR
IIH SUBUNIT TFB1
(Saccharomyces
cerevisiae) 		3 / 3 ARG 1  30
ILE 1  16
TRP 1  29
 None
 0.87A 2nodB-5oqm1:
undetectable		 2nodB-5oqm1:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQT_A_AINA596_1
(LACTOPEROXIDASE)		 5oqm GENERAL
TRANSCRIPTION AND
DNA REPAIR FACTOR
IIH HELICASE SUBUNIT
XPB
(Saccharomyces
cerevisiae) 		4 / 6 ARG 7 757
GLU 7 564
PHE 7 565
PRO 7 585
 None
 1.36A 2qqtA-5oqm7:
undetectable		 2qqtA-5oqm7:
8.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN0_A_TDZA501_1
(CYTOCHROME P450 2C8)		 5oqm TRANSCRIPTION FACTOR
TFIIE SUBUNIT
(Saccharomyces
cerevisiae) 		5 / 12 PHE W  15
LEU W  12
ASN W  11
VAL W 102
ILE W   8
 None
 1.17A 2vn0A-5oqmW:
undetectable		 2vn0A-5oqmW:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_1
(NON-STRUCTURAL
PROTEIN 5)		 5oqm RNA POLYMERASE II
TRANSCRIPTION FACTOR
B SUBUNIT 3
(Saccharomyces
cerevisiae) 		3 / 3 SER 3  41
HIS 3  36
ASP 3  60
 ZN  3 401 ( 4.7A)
ZN  3 402 (-3.3A)
None
 0.73A 2wa2B-5oqm3:
undetectable		 2wa2B-5oqm3:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_H_CPFH1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 5oqm GENERAL
TRANSCRIPTION AND
DNA REPAIR FACTOR
IIH HELICASE SUBUNIT
XPB
(Saccharomyces
cerevisiae) 		3 / 3 ARG 7 681
GLU 7 520
SER 7 707
 None
 0.88A 2xctD-5oqm7:
undetectable		 2xctD-5oqm7:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5oqm GENERAL
TRANSCRIPTION AND
DNA REPAIR FACTOR
IIH SUBUNIT TFB1
(Saccharomyces
cerevisiae) 		4 / 8 LEU 1  60
PHE 1  91
THR 1  28
LEU 1  27
 None
 0.67A 3ag3N-5oqm1:
3.5
3ag3W-5oqm1:
undetectable		 3ag3N-5oqm1:
undetectable
3ag3W-5oqm1:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJM_A_BJMA1_1
(DIPEPTIDYL PEPTIDASE
4)		 5oqm GENERAL
TRANSCRIPTION AND
DNA REPAIR FACTOR
IIH HELICASE SUBUNIT
XPB
(Saccharomyces
cerevisiae) 		5 / 12 GLU 7 572
TYR 7 581
TYR 7 569
ASN 7 767
VAL 7 763
 None
 1.26A 3bjmA-5oqm7:
undetectable		 3bjmA-5oqm7:
8.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_2
(PHOSPHOLIPASE A2)		 5oqm GENERAL
TRANSCRIPTION AND
DNA REPAIR FACTOR
IIH HELICASE SUBUNIT
XPB
(Saccharomyces
cerevisiae) 		4 / 5 VAL 7 657
GLN 7 672
PHE 7 626
ARG 7 722
 None
 1.09A 3bjwH-5oqm7:
undetectable		 3bjwH-5oqm7:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_2
(PHOSPHOLIPASE A2)		 5oqm GENERAL
TRANSCRIPTION AND
DNA REPAIR FACTOR
IIH HELICASE SUBUNIT
XPB
(Saccharomyces
cerevisiae) 		4 / 6 VAL 7 657
GLN 7 672
PHE 7 626
ARG 7 722
 None
 1.15A 3bjwF-5oqm7:
undetectable		 3bjwF-5oqm7:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_2
(PHOSPHOLIPASE A2)		 5oqm GENERAL
TRANSCRIPTION AND
DNA REPAIR FACTOR
IIH HELICASE SUBUNIT
XPB
(Saccharomyces
cerevisiae) 		4 / 5 VAL 7 657
GLN 7 672
PHE 7 626
ARG 7 722
 None
 0.97A 3bjwB-5oqm7:
undetectable		 3bjwB-5oqm7:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E68_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5oqm GENERAL
TRANSCRIPTION AND
DNA REPAIR FACTOR
IIH SUBUNIT TFB1
(Saccharomyces
cerevisiae) 		3 / 3 ARG 1  30
ILE 1  16
TRP 1  29
 None
 1.09A 3e68A-5oqm1:
undetectable		 3e68A-5oqm1:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E6T_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5oqm GENERAL
TRANSCRIPTION AND
DNA REPAIR FACTOR
IIH SUBUNIT TFB1
(Saccharomyces
cerevisiae) 		3 / 3 ARG 1  30
ILE 1  16
TRP 1  29
 None
 1.03A 3e6tB-5oqm1:
undetectable		 3e6tB-5oqm1:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7I_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5oqm GENERAL
TRANSCRIPTION AND
DNA REPAIR FACTOR
IIH SUBUNIT TFB1
(Saccharomyces
cerevisiae) 		3 / 3 ARG 1  30
ILE 1  16
TRP 1  29
 None
 0.95A 3e7iB-5oqm1:
undetectable		 3e7iB-5oqm1:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_A_T22A800_1
(DIPEPTIDYL PEPTIDASE
4)		 5oqm GENERAL
TRANSCRIPTION AND
DNA REPAIR FACTOR
IIH HELICASE SUBUNIT
XPB
(Saccharomyces
cerevisiae) 		5 / 12 GLU 7 572
TYR 7 581
TYR 7 569
ASN 7 767
VAL 7 763
 None
 1.24A 3g0bA-5oqm7:
undetectable		 3g0bA-5oqm7:
8.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCL_A_AINA609_1
(LACTOPEROXIDASE)		 5oqm GENERAL
TRANSCRIPTION AND
DNA REPAIR FACTOR
IIH HELICASE SUBUNIT
XPB
(Saccharomyces
cerevisiae) 		4 / 6 ARG 7 757
GLU 7 564
PHE 7 565
PRO 7 585
 None
 1.35A 3gclA-5oqm7:
undetectable		 3gclA-5oqm7:
8.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_A_LYAA514_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 5oqm GENERAL
TRANSCRIPTION AND
DNA REPAIR FACTOR
IIH SUBUNIT TFB1
(Saccharomyces
cerevisiae) 		5 / 12 ALA 1  50
LEU 1  62
ILE 1  16
LEU 1  27
LEU 1 104
 None
 1.12A 3k2hA-5oqm1:
undetectable		 3k2hA-5oqm1:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5oqm GENERAL
TRANSCRIPTION AND
DNA REPAIR FACTOR
IIH SUBUNIT TFB1
(Saccharomyces
cerevisiae) 		3 / 3 ARG 1  30
ILE 1  16
TRP 1  29
 None
 1.00A 3nw2A-5oqm1:
undetectable		 3nw2A-5oqm1:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5oqm GENERAL
TRANSCRIPTION AND
DNA REPAIR FACTOR
IIH SUBUNIT TFB1
(Saccharomyces
cerevisiae) 		3 / 3 ARG 1  30
ILE 1  16
TRP 1  29
 None
 0.87A 3nw2B-5oqm1:
undetectable		 3nw2B-5oqm1:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R4X_A_PZAA598_0
(LACTOPEROXIDASE)		 5oqm GENERAL
TRANSCRIPTION AND
DNA REPAIR FACTOR
IIH HELICASE SUBUNIT
XPB
(Saccharomyces
cerevisiae) 		4 / 5 ARG 7 757
GLU 7 564
PHE 7 565
PRO 7 585
 None
 1.49A 3r4xA-5oqm7:
undetectable		 3r4xA-5oqm7:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB323_0
(INVASIN IPAD)		 5oqm TRANSCRIPTION FACTOR
TFIIE SUBUNIT
(Saccharomyces
cerevisiae) 		4 / 7 ILE W  98
ILE W  95
VAL W   9
LEU W  12
 None
 0.69A 3r9vA-5oqmW:
undetectable
3r9vB-5oqmW:
2.3		 3r9vA-5oqmW:
undetectable
3r9vB-5oqmW:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_A_DXCA91_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5oqm MEDIATOR OF RNA
POLYMERASE II
TRANSCRIPTION
SUBUNIT 31,MEDIATOR
OF RNA POLYMERASE II
TRANSCRIPTION
SUBUNIT 31
(Saccharomyces
cerevisiae) 		3 / 3 PHE o  57
GLN o  49
PHE o  32
 None
 0.84A 3rv5A-5oqmo:
undetectable		 3rv5A-5oqmo:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA1001_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 5oqm GENERAL
TRANSCRIPTION AND
DNA REPAIR FACTOR
IIH HELICASE SUBUNIT
XPB
(Saccharomyces
cerevisiae) 		4 / 5 LEU 7 527
GLY 7 525
PHE 7 529
ARG 7 499
 None
 1.18A 3smtA-5oqm7:
undetectable		 3smtA-5oqm7:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_D_VK3D202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 5oqm MEDIATOR OF RNA
POLYMERASE II
TRANSCRIPTION
SUBUNIT 31,MEDIATOR
OF RNA POLYMERASE II
TRANSCRIPTION
SUBUNIT 31
(Saccharomyces
cerevisiae) 		4 / 5 ARG o  25
TYR o  66
TYR o  63
LEU o  64
 None
 1.40A 4f8yC-5oqmo:
undetectable
4f8yD-5oqmo:
undetectable		 4f8yC-5oqmo:
15.26
4f8yD-5oqmo:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MGH_A_ACTA1320_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 5oqm GENERAL
TRANSCRIPTION AND
DNA REPAIR FACTOR
IIH HELICASE SUBUNIT
XPB
(Saccharomyces
cerevisiae) 		4 / 5 VAL 7 493
LEU 7 487
ILE 7 531
LEU 7 530
 None
 0.85A 4mghA-5oqm7:
2.4		 4mghA-5oqm7:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_C_377C401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5oqm MEDIATOR OF RNA
POLYMERASE II
TRANSCRIPTION
SUBUNIT 31,MEDIATOR
OF RNA POLYMERASE II
TRANSCRIPTION
SUBUNIT 31
(Saccharomyces
cerevisiae) 		4 / 6 TYR o  66
TYR o  60
LEU o  61
PHE o  32
 None
 1.08A 4twdB-5oqmo:
undetectable
4twdC-5oqmo:
undetectable		 4twdB-5oqmo:
12.93
4twdC-5oqmo:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_E_377E401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5oqm MEDIATOR OF RNA
POLYMERASE II
TRANSCRIPTION
SUBUNIT 31,MEDIATOR
OF RNA POLYMERASE II
TRANSCRIPTION
SUBUNIT 31
(Saccharomyces
cerevisiae) 		4 / 6 TYR o  66
TYR o  60
LEU o  61
PHE o  32
 None
 1.00A 4twdD-5oqmo:
3.5
4twdE-5oqmo:
undetectable		 4twdD-5oqmo:
12.93
4twdE-5oqmo:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_F_377F401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5oqm MEDIATOR OF RNA
POLYMERASE II
TRANSCRIPTION
SUBUNIT 31,MEDIATOR
OF RNA POLYMERASE II
TRANSCRIPTION
SUBUNIT 31
(Saccharomyces
cerevisiae) 		4 / 7 TYR o  60
LEU o  61
PHE o  32
TYR o  66
 None
 1.11A 4twdF-5oqmo:
undetectable
4twdJ-5oqmo:
undetectable		 4twdF-5oqmo:
12.93
4twdJ-5oqmo:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_G_377G401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5oqm MEDIATOR OF RNA
POLYMERASE II
TRANSCRIPTION
SUBUNIT 31,MEDIATOR
OF RNA POLYMERASE II
TRANSCRIPTION
SUBUNIT 31
(Saccharomyces
cerevisiae) 		4 / 6 TYR o  66
TYR o  60
LEU o  61
PHE o  32
 None
 1.06A 4twdF-5oqmo:
undetectable
4twdG-5oqmo:
undetectable		 4twdF-5oqmo:
12.93
4twdG-5oqmo:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_J_377J401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5oqm MEDIATOR OF RNA
POLYMERASE II
TRANSCRIPTION
SUBUNIT 31,MEDIATOR
OF RNA POLYMERASE II
TRANSCRIPTION
SUBUNIT 31
(Saccharomyces
cerevisiae) 		4 / 6 TYR o  66
TYR o  60
LEU o  61
PHE o  32
 None
 1.13A 4twdI-5oqmo:
undetectable
4twdJ-5oqmo:
undetectable		 4twdI-5oqmo:
12.93
4twdJ-5oqmo:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XZK_A_AG2A700_1
(PUTATIVE
NAD(+)--ARGININE
ADP-RIBOSYLTRANSFERA
SE VIS)		 5oqm GENERAL
TRANSCRIPTION AND
DNA REPAIR FACTOR
IIH HELICASE SUBUNIT
XPB
(Saccharomyces
cerevisiae) 		4 / 7 SER 7 675
ARG 7 681
SER 7 679
GLU 7 683
 None
 1.39A 4xzkA-5oqm7:
undetectable		 4xzkA-5oqm7:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y1D_D_DVAD5_0
(CYCLIC HEXAPEPTIDE
CYC[NDPOPPKID]
INTEGRASE)		 5oqm MEDIATOR OF RNA
POLYMERASE II
TRANSCRIPTION
SUBUNIT 11
(Saccharomyces
cerevisiae) 		3 / 3 GLU c  42
LYS c  45
ASN c  41
 None
 0.87A 4y1dA-5oqmc:
undetectable
4y1dD-5oqmc:
undetectable		 4y1dA-5oqmc:
undetectable
4y1dD-5oqmc:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQE_A_NMYA600_1
(BIFUNCTIONAL AAC/APH)		 5oqm GENERAL
TRANSCRIPTION AND
DNA REPAIR FACTOR
IIH HELICASE SUBUNIT
XPB
(Saccharomyces
cerevisiae) 		5 / 11 ASP 7 728
SER 7 707
GLU 7 556
GLU 7 683
GLU 7 520
 None
 1.46A 5iqeA-5oqm7:
undetectable		 5iqeA-5oqm7:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_A_SALA301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 5oqm GENERAL
TRANSCRIPTION AND
DNA REPAIR FACTOR
IIH HELICASE SUBUNIT
XPB
(Saccharomyces
cerevisiae) 		4 / 5 ALA 7 399
VAL 7 395
PHE 7 484
ILE 7 384
 None
 0.75A 5of1A-5oqm7:
undetectable		 5of1A-5oqm7:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_B_SALB301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 5oqm GENERAL
TRANSCRIPTION AND
DNA REPAIR FACTOR
IIH HELICASE SUBUNIT
XPB
(Saccharomyces
cerevisiae) 		4 / 5 ALA 7 399
VAL 7 395
PHE 7 484
ILE 7 384
 None
 0.80A 5of1B-5oqm7:
undetectable		 5of1B-5oqm7:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5oqm GENERAL
TRANSCRIPTION AND
DNA REPAIR FACTOR
IIH SUBUNIT TFB1
(Saccharomyces
cerevisiae) 		4 / 8 LEU 1  60
PHE 1  91
THR 1  28
LEU 1  27
 None
 0.68A 5zcoA-5oqm1:
undetectable
5zcoJ-5oqm1:
undetectable		 5zcoA-5oqm1:
undetectable
5zcoJ-5oqm1:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5oqm GENERAL
TRANSCRIPTION AND
DNA REPAIR FACTOR
IIH SUBUNIT TFB1
(Saccharomyces
cerevisiae) 		4 / 8 ASN 1  92
PHE 1  91
ASN 1  99
ASP 1  98
 None
 1.19A 6auuB-5oqm1:
undetectable		 6auuB-5oqm1:
undetectable