SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5oqp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_B_RTLB501_0
(RETINOL DEHYDRATASE)		 5oqp CONDENSIN COMPLEX
SUBUNIT 3
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 833
LEU A 896
SER A 876
LEU A 829
ILE A 858
 None
 1.14A 1fmlB-5oqpA:
undetectable		 1fmlB-5oqpA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_A_ESTA600_1
(ESTROGEN RECEPTOR)		 5oqp CONDENSIN COMPLEX
SUBUNIT 3
(Saccharomyces
cerevisiae) 		5 / 11 LEU A 159
LEU A 158
MET A 145
ILE A 144
LEU A 138
 None
 1.23A 1g50A-5oqpA:
undetectable		 1g50A-5oqpA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRL_B_DOLB301_1
(STREPTOGRAMIN A
ACETYLTRANSFERASE)		 5oqp CONDENSIN COMPLEX
SUBUNIT 3
(Saccharomyces
cerevisiae) 		5 / 12 TYR A 839
ASN A 854
LEU A 773
VAL A 888
ASP A 886
 None
 1.49A 1mrlB-5oqpA:
undetectable
1mrlC-5oqpA:
undetectable		 1mrlB-5oqpA:
12.43
1mrlC-5oqpA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_B_CIAB2003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5oqp CONDENSIN COMPLEX
SUBUNIT 3
(Saccharomyces
cerevisiae) 		5 / 12 ALA A  53
ILE A  13
VAL A  17
ALA A  18
PHE A  21
 1PE  A1001 ( 3.8A)
None
None
None
None
 0.88A 1uduB-5oqpA:
undetectable		 1uduB-5oqpA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 5oqp CONDENSIN COMPLEX
SUBUNIT 3
(Saccharomyces
cerevisiae) 		4 / 5 PHE A 118
PHE A 114
PHE A  54
VAL A  62
 None
 1.09A 2lh6A-5oqpA:
undetectable		 2lh6A-5oqpA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 5oqp CONDENSIN COMPLEX
SUBUNIT 3
(Saccharomyces
cerevisiae) 		5 / 12 TYR A 434
ILE A 465
GLY A 464
ALA A 429
ASN A 449
 None
 1.01A 3jb3A-5oqpA:
2.5		 3jb3A-5oqpA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_C_9PLC501_1
(CYTOCHROME P450 2A6)		 5oqp CONDENSIN COMPLEX
SUBUNIT 3
(Saccharomyces
cerevisiae) 		5 / 9 PHE A 114
PHE A 111
PHE A  58
ILE A  86
PHE A  54
 None
 1.13A 3t3rC-5oqpA:
undetectable		 3t3rC-5oqpA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_2
(CARBONIC ANHYDRASE)		 5oqp CONDENSIN COMPLEX
SUBUNIT 3
(Saccharomyces
cerevisiae) 		5 / 10 CYH A 750
CYH A 711
GLY A 709
ALA A 707
ALA A 706
 None
 1.16A 3ucjB-5oqpA:
undetectable		 3ucjB-5oqpA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5oqp CONDENSIN COMPLEX
SUBUNIT 3
(Saccharomyces
cerevisiae) 		4 / 5 PHE A 118
LEU A  66
ILE A 144
VAL A 143
 None
 0.73A 3wrkA-5oqpA:
undetectable		 3wrkA-5oqpA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_F_BEZF501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 5oqp CONDENSIN COMPLEX
SUBUNIT 3
(Saccharomyces
cerevisiae) 		4 / 8 ALA A 428
SER A 426
LEU A 388
TYR A 434
 None
 1.13A 4ijiF-5oqpA:
5.4		 4ijiF-5oqpA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM6_A_29EA603_1
(TRANSPORTER)		 5oqp CONDENSIN COMPLEX
SUBUNIT 3
(Saccharomyces
cerevisiae) 		5 / 12 ASP A  59
VAL A  17
ALA A  18
PHE A 114
PHE A  54
 None
 1.11A 4mm6A-5oqpA:
2.6		 4mm6A-5oqpA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 5oqp CONDENSIN COMPLEX
SUBUNIT 3
(Saccharomyces
cerevisiae) 		3 / 3 PRO A 459
LEU A 460
GLN A 424
 None
 0.59A 4pevB-5oqpA:
undetectable		 4pevB-5oqpA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_B_RTLB201_0
(RETINOL-BINDING
PROTEIN 2)		 5oqp CONDENSIN COMPLEX
SUBUNIT 3
(Saccharomyces
cerevisiae) 		5 / 12 PHE A 276
ILE A 299
LEU A 298
LEU A 241
LEU A 279
 None
 1.28A 4qynB-5oqpA:
undetectable		 4qynB-5oqpA:
9.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_D_ACTD403_0
(D-ALANINE--D-ALANINE
LIGASE)		 5oqp CONDENSIN COMPLEX
SUBUNIT 3
(Saccharomyces
cerevisiae) 		4 / 6 TYR A 839
LYS A 848
SER A 889
LEU A 885
 None
 1.27A 5bphD-5oqpA:
undetectable		 5bphD-5oqpA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNZ_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 5oqp CONDENSIN COMPLEX
SUBUNIT 3
(Saccharomyces
cerevisiae) 		5 / 12 ASP A 433
ASP A 371
ALA A 428
PHE A 362
PRO A 383
 None
 1.41A 5hnzB-5oqpA:
undetectable		 5hnzB-5oqpA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HV1_A_RFPA902_1
(PHOSPHOENOLPYRUVATE
SYNTHASE)		 5oqp CONDENSIN COMPLEX
SUBUNIT 3
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 637
VAL A 674
LEU A 686
LEU A 628
ILE A 658
 None
 1.17A 5hv1A-5oqpA:
4.1		 5hv1A-5oqpA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_1
(CDL2.3B)		 5oqp CONDENSIN COMPLEX
SUBUNIT 3
(Saccharomyces
cerevisiae) 		5 / 12 PHE A 268
TRP A 303
PHE A 276
ALA A 329
LEU A 284
 None
 1.23A 5iepA-5oqpA:
undetectable		 5iepA-5oqpA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JI0_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5oqp CONDENSIN COMPLEX
SUBUNIT 3
(Saccharomyces
cerevisiae) 		5 / 11 LEU A 626
LEU A 606
ALA A 610
VAL A 479
LEU A 593
 None
 1.14A 5ji0A-5oqpA:
undetectable		 5ji0A-5oqpA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_1
(PAVINE
N-METHYLTRANSFERASE)		 5oqp CONDENSIN COMPLEX
SUBUNIT 3
(Saccharomyces
cerevisiae) 		4 / 5 SER A  88
ASN A  55
GLN A  42
ASP A  59
 None
 1.35A 5kpcA-5oqpA:
undetectable		 5kpcA-5oqpA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYC_A_1YNA502_2
(PROTEIN CYP51)		 5oqp CONDENSIN COMPLEX
SUBUNIT 3
(Saccharomyces
cerevisiae) 		4 / 7 VAL A 835
LEU A 724
PHE A 725
LEU A 730
 None
 1.19A 6aycA-5oqpA:
undetectable		 6aycA-5oqpA:
6.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 5oqp CONDENSIN COMPLEX
SUBUNIT 3
(Saccharomyces
cerevisiae) 		4 / 6 LEU A 724
ASP A 771
GLN A 841
GLU A 726
 None
 1.43A 6djzC-5oqpA:
undetectable		 6djzC-5oqpA:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA813_0
(GEPHYRIN)		 5oqp CONDENSIN COMPLEX
SUBUNIT 3
(Saccharomyces
cerevisiae) 		3 / 3 THR A 574
ALA A 570
LYS A 568
 None
 0.74A 6fgcA-5oqpA:
undetectable		 6fgcA-5oqpA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA817_0
(GEPHYRIN)		 5oqp CONDENSIN COMPLEX
SUBUNIT 3
(Saccharomyces
cerevisiae) 		3 / 3 THR A 574
ALA A 570
LYS A 568
 None
 0.76A 6fgdA-5oqpA:
undetectable		 6fgdA-5oqpA:
18.78